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Recently, shoot-through proton FLASH has been proposed where the highest energy is extracted from the cyclotron to maximize the dose rate (DR). Even though our proton pencil beam scanning system can deliver 250 MeV (the highest energy), it…

Medical Physics · Physics 2023-01-26 Serdar Charyyev , Chih-Wei Chang , Mingyao Zhu , Liyong Lin , Katja Langen , Anees Dhabaan

Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

In this paper, we propose a method based on GMM (the generalized method of moments) to estimate the parameters of stable distributions with $0<\alpha<2$. We don't assume symmetry for stable distributions.

Statistics Theory · Mathematics 2007-06-13 Chunlin Wang

We carry out a comprehensive linear stability analysis of active Brownian particle systems around a constant homogeneous state. These scalar models, being important prototypes for the continuous description of active matter, are…

Analysis of PDEs · Mathematics 2025-12-22 Michele Coti Zelati , Lucas Ertzbischoff , David Gerard-Varet

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

Particle physics simulations are the cornerstone of nuclear engineering applications. Among them radiotherapy (RT) is crucial for society, with 50% of cancer patients receiving radiation treatments. For the most precise targeting of tumors,…

Machine Learning · Computer Science 2021-09-10 Oscar Pastor-Serrano , Zoltán Perkó

We present the results on the source spectrum function for primary nuclei in galactic cosmic rays, where two distinct energy dependences are used for the source spectra. We discuss the evolution of the goodness of fit to B/C data with the…

Astrophysics · Physics 2007-05-23 Fiorenza Donato , David Maurin , Richard Taillet

A model for beam customization with collimators and a range-compensating filter based on the phase-space theory for beam transport is presented for dose distribution calculation in treatment planning of radiotherapy with protons and heavier…

Medical Physics · Physics 2008-05-27 Nobuyuki Kanematsu , Shunsuke Yonai , Azusa Ishizaki , Masami Torikoshi

We demonstrate that the matter density distribution in the surface region is determined well by the use of the relatively low-intensity beams that become available at the upcoming radioactive beam facilities. Following the method used in…

Nuclear Theory · Physics 2009-11-07 Akihisa Kohama , Ryoichi Seki , Akito Arima , Shuhei Yamaji

We derive an equation whose solutions describe self-consistent states of marginal stability for a proton-electron plasma interacting with parallel-propagating ion cyclotron waves. Ion cyclotron waves propagating through this marginally…

Plasma Physics · Physics 2015-06-04 Philip A. Isenberg

Purpose: To describe the dosimetric commissioning and quality assurance (QA) of the actively scanned proton and carbon ion beams at the Italian National Center for Oncological Hadrontherapy. Methods: The laterally integrated…

The stability of weakly collisional plasmas is well represented by linear theory, and the generated waves play an essential role in the thermodynamics of these systems. The velocity distribution functions (VDF) characterizing kinetic…

Solar and Stellar Astrophysics · Physics 2024-12-09 Mihailo M. Martinović , Kristopher G. Klein , Rossana De Marco , Daniel Verscharen , Raffaella D'Amicis , Roberto Bruno

The advanced imaging and delivery techniques in proton therapy allow conformal high-dose irradiation of the target volume with high accuracy using pencil beam scanning or beam shaping apertures. These irradiation methods increasingly…

We study the transport and deposition dynamics of colloids in saturated porous media under unfavorable filtering conditions. As an alternative to traditional convection-diffusion or more detailed numerical models, we consider a mean-field…

Soft Condensed Matter · Physics 2009-05-13 Hsiang-Ku Lin , Leonid P. Pryadko , Sharon Walker , Roya Zandi

Accurate 3D dose calculation for Pencil Beam Scanning Proton Therapy (PBSPT) is typically performed with Monte Carlo (MC) engines, but their runtimes limit adaptive workflows and repeated evaluations. Current deep-learning proton dose…

Medical Physics · Physics 2026-02-19 Mikołaj Stryja , Danny Lathouwers , Zoltán Perkó

Purpose: The importance of robust proton treatment planning to mitigate the impact of uncertainty is well understood. However, its computational cost grows with the number of uncertainty scenarios, prolonging the treatment planning process.…

Medical Physics · Physics 2023-05-01 Anqi Fu , Vicki T. Taasti , Masoud Zarepisheh

Steady state distribution functions can be used to calculate stability conditions for modes, radiation energy losses, and particle loss rates. Heuristic analytic approximations to these distributions can capture key behaviors of the true…

Plasma Physics · Physics 2025-09-23 Greta X. Li , Elijah J. Kolmes , Ian E. Ochs , Nathaniel J. Fisch

We performed a least-square fit analysis to reproduce the elastic angular distributions for $\alpha$ scattering on various nuclei form $^{12}$C to $^{208}$Pb for incident energies in the range 18 - 70 MeV using a velocity-dependent optical…

Nuclear Theory · Physics 2024-04-16 A. Saleh , M. I. Jaghoub

Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…