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ABIDE is the largest open-source autism spectrum disorder database with both fMRI data and full phenotype description. These data were extensively studied based on functional connectivity analysis as well as with deep learning on raw data,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-15 Marina Pominova , Ekaterina Kondrateva , Maxim Sharaev , Alexander Bernstein , Evgeny Burnaev

The problem of jointly analysing functional connectomics and behavioral data is extremely challenging owing to the complex interactions between the two domains. In addition, clinical rs-fMRI studies often have to contend with limited…

Machine Learning · Computer Science 2023-01-18 Niharika Shimona D'Souza

Autism spectrum disorder(ASD) is a lifelong neurodevelopmental condition that affects social communication and behavior. Investigating functional magnetic resonance imaging (fMRI)-based brain functional connectome can aid in the…

Neurons and Cognition · Quantitative Biology 2023-07-21 Anushree Bannadabhavi , Soojin Lee , Wenlong Deng , Xiaoxiao Li

The multifactorial etiology of autism spectrum disorder (ASD) suggests that its study would benefit greatly from multimodal approaches that combine data from widely varying platforms, e.g., neuroimaging, genetics, and clinical…

Quantitative Methods · Quantitative Biology 2023-08-11 Nicha C. Dvornek , Catherine Sullivan , James S. Duncan , Abha R. Gupta

Autism spectrum disorder (ASD) is a neurological and developmental disorder that affects social and communicative behaviors. It emerges in early life and is generally associated with lifelong disabilities. Thus, accurate and early diagnosis…

Image and Video Processing · Electrical Eng. & Systems 2025-02-24 Peiyu Duan , Nicha C. Dvornek , Jiyao Wang , Lawrence H. Staib , James S. Duncan

Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…

Neurons and Cognition · Quantitative Biology 2025-09-24 Ali Khazaee , Abdolreza Mohammadi , Ruairi O'Reilly

Connectivity studies using resting-state functional magnetic resonance imaging are increasingly pooling data acquired at multiple sites. While this may allow investigators to speed up recruitment or increase sample size, multisite studies…

Quantitative Methods · Quantitative Biology 2017-02-10 Christian Dansereau , Yassine Benhajali , Celine Risterucci , Emilio Merlo Pich , Pierre Orban , Douglas Arnold , Pierre Bellec

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

Neurons and Cognition · Quantitative Biology 2025-12-30 Ashley Chen

Determining biomarkers for autism spectrum disorder (ASD) is crucial to understanding its mechanisms. Recently deep learning methods have achieved success in the classification task of ASD using fMRI data. However, due to the black-box…

Computer Vision and Pattern Recognition · Computer Science 2019-10-14 Juntang Zhuang , Nicha C. Dvornek , Xiaoxiao Li , Pamela Ventola , James S. Duncan

This paper presents a comprehensive and quality collection of functional human brain network data for potential research in the intersection of neuroscience, machine learning, and graph analytics. Anatomical and functional MRI images have…

Traditional causal connectivity methods in task-based and resting-state functional magnetic resonance imaging (fMRI) face challenges in accurately capturing directed information flow due to their sensitivity to noise and inability to model…

Neurons and Cognition · Quantitative Biology 2025-04-03 Boseong Kim , Debashis Das Chakladar , Haejun Chung , Ikbeom Jang

Autism Spectrum Condition (ASC) is a neurodevelopmental condition characterized by impairments in communication, social interaction and restricted or repetitive behaviors. Extensive research has been conducted to identify distinctions…

Quantitative Methods · Quantitative Biology 2024-05-22 F. J. Alcaide , I. A. Illan , J. Ramirez , J. M. Gorriz

Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Javier Salazar Cavazos , Maximillian Egan , Krisanne Litinas , Benjamin Hampstead , Scott Peltier

A reliable foundation model of functional neuroimages is critical to promote clinical applications where the performance of current AI models is significantly impeded by a limited sample size. To that end, tremendous efforts have been made…

Machine Learning · Computer Science 2025-10-23 Ziquan Wei , Tingting Dan , Guorong Wu

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Psychiatric research has been hampered by an explanatory gap between psychiatric symptoms and their neural underpinnings, which has resulted in poor treatment outcomes. This situation has prompted us to shift from symptom-based diagnosis to…

Autism Spectrum Disorder (ASD) is a pervasive developmental disorder of the central nervous system, primarily manifesting in childhood. It is characterized by atypical and repetitive behaviors. Currently, diagnostic methods mainly rely on…

Neurons and Cognition · Quantitative Biology 2025-03-21 Yiqian Luo , Qiurong Chen , Fali Li , Liang Yi , Peng Xu , Yangsong Zhang

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder, and behavioral treatment interventions have shown promise for young children with ASD. However, there is limited progress in understanding the effect of each type of…

Neurons and Cognition · Quantitative Biology 2019-09-04 Juntang Zhuang , Nicha C. Dvornek , Qingyu Zhao , Xiaoxiao Li , Pamela Ventola , James S. Duncan

These days, computational diagnosis strategies of neuropsychiatric disorders are gaining attention day by day. It's critical to determine the brain's functional connectivity based on Functional-Magnetic-Resonance-Imaging(fMRI) to diagnose…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Sartaj Ahmed Salman , Zhichao Lian , Marva Saleem , Yuduo Zhang

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

Neurons and Cognition · Quantitative Biology 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq