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Related papers: GENESIM: genetic extraction of a single, interpret…

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Gradient boosted trees and other regression tree models perform well in a wide range of real-world, industrial applications. These tree models (i) offer insight into important prediction features, (ii) effectively manage sparse data, and…

Machine Learning · Statistics 2021-05-19 Alexander Thebelt , Jan Kronqvist , Miten Mistry , Robert M. Lee , Nathan Sudermann-Merx , Ruth Misener

Inferring Gene Regulatory Networks (GRNs) from gene expression data is crucial for understanding biological processes. While supervised models are reported to achieve high performance for this task, they rely on costly ground truth (GT)…

Machine Learning · Statistics 2025-06-10 Tianyu Cui , Song-Jun Xu , Artem Moskalev , Shuwei Li , Tommaso Mansi , Mangal Prakash , Rui Liao

Ensembling a neural network is a widely recognized approach to enhance model performance, estimate uncertainty, and improve robustness in deep supervised learning. However, deep ensembles often come with high computational costs and memory…

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

Genetic programming systems often use large training sets to evaluate the quality of candidate solutions for selection, which is often computationally expensive. Down-sampling training sets has long been used to decrease the computational…

Neural and Evolutionary Computing · Computer Science 2024-08-02 Ryan Boldi , Ashley Bao , Martin Briesch , Thomas Helmuth , Dominik Sobania , Lee Spector , Alexander Lalejini

This paper develops an approach to classify instances of product failure in a complex textiles manufacturing dataset using explainable techniques. The dataset used in this study was obtained from a New Zealand manufacturer of woollen…

Machine Learning · Computer Science 2024-07-29 Briony Forsberg , Dr Henry Williams , Prof Bruce MacDonald , Tracy Chen , Dr Reza Hamzeh , Dr Kirstine Hulse

Despite the recent remarkable advances in neural machine translation, translation quality for low-resource language pairs remains subpar. Ensembling multiple systems is a widely adopted technique to enhance performance, often accomplished…

Computation and Language · Computer Science 2026-03-10 Seokjin Oh , Keonwoong Noh , Woohwan Jung

Tree ensembles (TEs) find a multitude of practical applications. They represent one of the most general and accurate classes of machine learning methods. While they are typically quite concise in representation, their operation remains…

Artificial Intelligence · Computer Science 2026-04-01 Yacine Izza , Alexey Ignatiev , Xuanxiang Huang , Peter J. Stuckey , Joao Marques-Silva

The motivation of this work is to improve the performance of standard stacking approaches or ensembles, which are composed of simple, heterogeneous base models, through the integration of the generation and selection stages for regression…

Machine Learning · Statistics 2014-03-31 Roberto Aldave , Jean-Pierre Dussault

We propose to use boosted regression trees as a way to compute human-interpretable solutions to reinforcement learning problems. Boosting combines several regression trees to improve their accuracy without significantly reducing their…

Machine Learning · Computer Science 2018-09-20 Alexander Brown , Marek Petrik

Generative Adversarial Networks (GANs) are popular tools for generative modeling. The dynamics of their adversarial learning give rise to convergence pathologies during training such as mode and discriminator collapse. In machine learning,…

Artificial Intelligence · Computer Science 2020-08-04 Jamal Toutouh , Erik Hemberg , Una-May O'Reilly

Summary: GeneSupport implements a genome-scale algorithm: Maximum Gene-Support Tree to estimate species tree from gene trees based on multilocus sequences. It provides a new option for multiple genes to infer species tree. It is…

Genomics · Quantitative Biology 2009-10-13 Yunfeng Shan , Xiu-Qing Li

Estimating heritability remains a significant challenge in statistical genetics. Diverse approaches have emerged over the years that are broadly categorized as either random effects or fixed effects heritability methods. In this work, we…

Methodology · Statistics 2024-06-18 Yanke Song , Xihong Lin , Pragya Sur

Causal discovery in multi-omic datasets is crucial for understanding the bigger picture of gene regulatory mechanisms, but remains challenging due to high dimensionality, differentiation of direct from indirect relationships, and hidden…

Genomics · Quantitative Biology 2025-05-23 Stephen Asiedu , David Watson

Although neural networks are a powerful tool, their widespread use is hindered by the opacity of their decisions and their black-box nature, which result in a lack of trustworthiness. To alleviate this problem, methods in the field of…

Machine Learning · Computer Science 2025-11-13 Helena Monke , Benjamin Fresz , Marco Bernreuther , Yilin Chen , Marco F. Huber

Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

Biomolecules · Quantitative Biology 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

Ensemble methods such as random forests have transformed the landscape of supervised learning, offering highly accurate prediction through the aggregation of multiple weak learners. However, despite their effectiveness, these methods often…

Machine Learning · Computer Science 2026-05-29 Massimo Aria , Agostino Gnasso , Carmela Iorio , Marjolein Fokkema

The field of machine learning is subject to an increasing interest in models that are not only accurate but also interpretable and robust, thus allowing their end users to understand and trust AI systems. This paper presents a novel method…

Machine Learning · Computer Science 2026-04-24 Valentin Lemaire , Gaël Aglin , Siegfried Nijssen

As a common method in Machine Learning, Ensemble Method is used to train multiple models from a data set and obtain better results through certain combination strategies. Stacking method, as representatives of Ensemble Learning methods, is…

Machine Learning · Computer Science 2020-09-15 Jiacheng Ruan , Jiahao Li

Introduction. We investigate the generalization ability of models built on datasets containing a small number of subjects, recorded in single study protocols. Next, we propose and evaluate methods combining these datasets into a single,…

Machine Learning · Computer Science 2023-12-05 Gideon Vos , Kelly Trinh , Zoltan Sarnyai , Mostafa Rahimi Azghadi