English
Related papers

Related papers: Label-free single molecule imaging with numerical …

200 papers

We introduce a non-exponential radiative framework that takes into account the local spatial correlation of scattering particles in a medium. Most previous works in graphics have ignored this, assuming uncorrelated media with a uniform,…

Graphics · Computer Science 2018-05-14 Adrian Jarabo , Carlos Aliaga , Diego Gutierrez

Three-dimensional phase contrast imaging of multiply-scattering samples in X-ray and electron microscopy is extremely challenging, due to small numerical apertures, the unavailability of wavefront shaping optics, and the highly nonlinear…

Computational Physics · Physics 2021-06-02 Philipp M Pelz , Hamish G Brown , Jim Ciston , Scott D Findlay , Yaqian Zhang , Mary Scott , Colin Ophus

We demonstrate that an effective near-zero refractive index can emerge from collective light scattering in a discrete atomic lattice, using essentially exact microscopic simulations. In a 25-layer array, cooperative response leads to over a…

Optics · Physics 2025-12-08 L. Ruks , J. Ruostekoski

The advent of single molecule optics has had a profound impact in fields ranging from biophysics to material science, photophysics, and quantum optics. However, all existing room-temperature single molecule methods have been based on…

Mesoscale and Nanoscale Physics · Physics 2010-07-22 Michele Celebrano , Philipp Kukura , Alois Renn , Vahid Sandoghdar

Imaging through complex scattering media is severely limited by aberrations and scattering which obscure images and reduce resolution. Confocal and temporal gatings partly filter out multiple scattering but are severely degraded by…

Optics · Physics 2026-05-18 Yiwen Zhang , Minh Dinh , Zeyu Wang , Tianhao Zhang , Tianhang Chen , Chia Wei Hsu

Due to the complex of mixed spectral point spread function within memory effect range, it is unreliable and slow to use speckle correlation technology for non-invasive imaging through scattering medium under broadband illumination. The…

Interstellar extinction includes both absorption and scattering of photons from interstellar gas and dust grains, and it has the effect of altering a source's spectrum and its total observed intensity. However, while multiple absorption…

High Energy Astrophysical Phenomena · Physics 2016-02-26 Randall K. Smith , Lynne A. Valencic , Lia Corrales

We report the modification of a label-free image scanning microscope (ISM) to perform asynchronous 2D imaging at 24kHz while keeping the lateral resolution gain and background rejection of a regular label-free ISM setup. Our method uses a…

Optics · Physics 2023-08-31 Duc-Minh Ta , Alberto Aguilar , Pierre Bon

We used a consistent and robust solar model to obtain upper limits placed by neutrino telescopes, such as Ice- Cube and Super-Kamiokande, on the Dark Matter-nucleon scattering cross-section, for a general model of Dark Matter with a…

Cosmology and Nongalactic Astrophysics · Physics 2016-09-30 José Lopes , Ilídio Lopes

Extinction spectroscopy is a powerful tool for demonstrating the coupling of a single quantum emitter to a photonic structure. However, it can be challenging in all but the simplest of geometries to deduce an accurate value of the coupling…

There is growing interest in the use of coded aperture imaging systems for a variety of applications. Using an analysis framework based on mutual information, we examine the fundamental limits of such systems---and the associated optimum…

Image and Video Processing · Electrical Eng. & Systems 2017-12-14 Adam Yedidia , Christos Thrampoulidis , Gregory Wornell

We consider imaging in a scattering medium where the illumination goes through this medium but there is also an auxiliary, passive receiver array that is near the object to be imaged. Instead of imaging with the source-receiver array on the…

Analysis of PDEs · Mathematics 2013-10-18 Josselin Garnier , George Papanicolaou

We present an experiment where a single molecule strongly affects the amplitude and phase of a laser field emerging from a subwavelength aperture. We achieve a visibility of -6% in direct and +10% in cross-polarized detection schemes. Our…

Quantum Physics · Physics 2007-05-23 I. Gerhardt , G. Wrigge , P. Bushev , G. Zumofen , R. Pfab , V. Sandoghdar

Single molecule imaging is one of the main target areas of X-ray free electron lasers. It relies on the possibility of orienting the large number of low counting statistics 2D diffraction patterns taken at random orientations of identical…

Atomic and Molecular Clusters · Physics 2012-11-30 Zoltan Jurek , Gyula Faigel

Interferometric scattering microscopy was widely applied in nanoscopic detection and tracking due to its high sensitivity and label-free manner. The sensitivity is limited by contrast. Oblique illumination provided high contrast with lower…

Optics · Physics 2025-11-11 Xiang Zhang , Wenfu Lin , Yatao Yang , Yifan Wang

Optical wavefront-shaping has emerged as a powerful tool to manipulate light in strongly scattering media. It enables diffraction-limited focusing and imaging at depths where conventional microscopy techniques fail. However, while most…

Optics · Physics 2014-03-04 T. Chaigne , O. Katz , A. C. Boccara , M. Fink , E. Bossy , S. Gigan

Direct imaging methods recover the presence, position, and shape of the unknown obstacles in time-harmonic inverse scattering without a priori knowledge of either the physical properties or the number of disconnected components of the…

Analysis of PDEs · Mathematics 2023-11-29 General Ozochiawaeze

Direct imaging of exoplanets is a challenging task as it requires to reach a high contrast at very close separation to the star. Today, the main limitation in the high-contrast images is the quasi-static speckles that are created by…

Instrumentation and Methods for Astrophysics · Physics 2019-05-22 Benoît Pairet , Faustine Cantalloube , Carlos A. Gomez Gonzalez , Olivier Absil , Laurent Jacques

We present scanning near-field extinction spectra of single molecules embedded in a solid matrix. By varying the molecule-tip separation, we modify the line shape of the spectra, demonstrating the coherent nature of the interaction between…

Optics · Physics 2009-11-13 I. Gerhardt , G. Wrigge , M. Agio , P. Bushev , G. Zumofen , V. Sandoghdar

Extending super-resolution imaging techniques to objects hidden in strongly scattering media potentially revolutionize the technical analysis for much broader categories of samples, such as biological tissues. The main challenge is the…