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Related papers: Low Data Drug Discovery with One-shot Learning

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Humans can infer a great deal about the meaning of a word, using the syntax and semantics of surrounding words even if it is their first time reading or hearing it. We can also generalise the learned concept of the word to new tasks.…

Computation and Language · Computer Science 2020-07-21 Talip Ucar , Adrian Gonzalez-Martin , Matthew Lee , Adrian Daniel Szwarc

Due to their excellent drug-like and pharmacokinetic properties, small molecule drugs are widely used to treat various diseases, making them a critical component of drug discovery. In recent years, with the rapid development of deep…

Machine Learning · Computer Science 2025-05-15 Kun Li , Yida Xiong , Hongzhi Zhang , Xiantao Cai , Jia Wu , Bo Du , Wenbin Hu

Few-shot learning has recently attracted significant interest in drug discovery, with a recent, fast-growing literature mostly involving convoluted meta-learning strategies. We revisit the more straightforward fine-tuning approach for…

Machine Learning · Computer Science 2025-02-10 Philippe Formont , Hugo Jeannin , Pablo Piantanida , Ismail Ben Ayed

Few-shot learning (FSL) techniques seek to learn the underlying patterns in data using fewer samples, analogous to how humans learn from limited experience. In this limited-data scenario, the challenges associated with deep neural networks,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Deepan Chakravarthi Padmanabhan , Shruthi Gowda , Elahe Arani , Bahram Zonooz

Drug discovery using deep learning has attracted a lot of attention of late as it has obvious advantages like higher efficiency, less manual guessing and faster process time. In this paper, we present a novel neural network for generating…

Biomolecules · Quantitative Biology 2021-10-08 Abhinav Sagar

Large machine-learning training datasets can be distilled into small collections of informative synthetic data samples. These synthetic sets support efficient model learning and reduce the communication cost of data sharing. Thus,…

Machine Learning · Computer Science 2024-08-13 William Holland , Chandra Thapa , Sarah Ali Siddiqui , Wei Shao , Seyit Camtepe

Deep neural networks have been extensively applied in the medical domain for various tasks, including image classification, segmentation, and landmark detection. However, their application is often hindered by data scarcity, both in terms…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Roberto Di Via , Francesca Odone , Vito Paolo Pastore

Convolutional neural networks (CNNs) have been widely used in the computer vision community, significantly improving the state-of-the-art. But learning good features often is computationally expensive in machine learning settings and is…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Janis Mohr , Jörg Frochte

Large pre-trained language models (LLMs) have been shown to have significant potential in few-shot learning across various fields, even with minimal training data. However, their ability to generalize to unseen tasks in more complex fields,…

Computation and Language · Computer Science 2023-04-24 Tianhao Li , Sandesh Shetty , Advaith Kamath , Ajay Jaiswal , Xianqian Jiang , Ying Ding , Yejin Kim

We propose regression networks for the problem of few-shot classification, where a classifier must generalize to new classes not seen in the training set, given only a small number of examples of each class. In high dimensional embedding…

Machine Learning · Computer Science 2020-06-22 Arnout Devos , Matthias Grossglauser

Few-shot learning is challenging for learning algorithms that learn each task in isolation and from scratch. In contrast, meta-learning learns from many related tasks a meta-learner that can learn a new task more accurately and faster with…

Machine Learning · Computer Science 2017-09-29 Zhenguo Li , Fengwei Zhou , Fei Chen , Hang Li

The recent success of graph neural networks has significantly boosted molecular property prediction, advancing activities such as drug discovery. The existing deep neural network methods usually require large training dataset for each…

Machine Learning · Computer Science 2021-02-17 Zhichun Guo , Chuxu Zhang , Wenhao Yu , John Herr , Olaf Wiest , Meng Jiang , Nitesh V. Chawla

The ability to learn from a small number of examples has been a difficult problem in machine learning since its inception. While methods have succeeded with large amounts of training data, research has been underway in how to accomplish…

Machine Learning · Computer Science 2017-08-24 Nathan Hilliard , Nathan O. Hodas , Courtney D. Corley

The selection of hyper-parameters is critical in Deep Learning. Because of the long training time of complex models and the availability of compute resources in the cloud, "one-shot" optimization schemes - where the sets of hyper-parameters…

Machine Learning · Computer Science 2017-06-13 Olivier Bousquet , Sylvain Gelly , Karol Kurach , Olivier Teytaud , Damien Vincent

Few-shot learning is a promising approach to molecular property prediction as supervised data is often very limited. However, many important molecular properties depend on complex molecular characteristics -- such as the various 3D…

Machine Learning · Computer Science 2023-10-10 Christopher Fifty , Joseph M. Paggi , Ehsan Amid , Jure Leskovec , Ron Dror

Conventional training of deep neural networks usually requires a substantial amount of data with expensive human annotations. In this paper, we utilize the idea of meta-learning to explain two very different streams of few-shot learning,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-13 Shaobo Lin , Xingyu Zeng , Rui Zhao

One-shot neural architecture search allows joint learning of weights and network architecture, reducing computational cost. We limit our search space to the depth of residual networks and formulate an analytically tractable variational…

Machine Learning · Statistics 2020-04-03 Javier Antorán , James Urquhart Allingham , José Miguel Hernández-Lobato

In this paper, we introduce the new ideas of augmenting Convolutional Neural Networks (CNNs) with Memory and learning to learn the network parameters for the unlabelled images on the fly in one-shot learning. Specifically, we present Memory…

Computer Vision and Pattern Recognition · Computer Science 2018-04-24 Qi Cai , Yingwei Pan , Ting Yao , Chenggang Yan , Tao Mei

This study explores the application potential of a deep learning model based on the CNN-LSTM framework in forecasting the sales volume of cancer drugs, with a focus on modeling complex time series data. As advancements in medical technology…

Computational Engineering, Finance, and Science · Computer Science 2025-06-30 Yinghan Li , Yilin Yao , Junghua Lin , Nanxi Wang

Few-shot learning is a relatively new technique that specializes in problems where we have little amounts of data. The goal of these methods is to classify categories that have not been seen before with just a handful of samples. Recent…