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The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

Labeled Latent Dirichlet Allocation (LLDA) is an extension of the standard unsupervised Latent Dirichlet Allocation (LDA) algorithm, to address multi-label learning tasks. Previous work has shown it to perform in par with other…

Machine Learning · Statistics 2017-09-19 Yannis Papanikolaou , Grigorios Tsoumakas

We propose a communication-efficient distributed estimation method for sparse linear discriminant analysis (LDA) in the high dimensional regime. Our method distributes the data of size $N$ into $m$ machines, and estimates a local sparse LDA…

Machine Learning · Statistics 2016-10-18 Lu Tian , Quanquan Gu

Owing to the advantages of increased accuracy and the potential to detect unseen patterns, provided by data mining techniques they have been widely incorporated for standard classification problems. They have often been used for high…

Machine Learning · Computer Science 2022-10-05 Anirudha Rayasam , Nagamma Patil

Label distribution learning (LDL) trains a model to predict the relevance of a set of labels (called label distribution (LD)) to an instance. The previous LDL methods all assumed the LDs of the training instances are accurate. However,…

Machine Learning · Computer Science 2023-08-29 Zhiqiang Kou , Yuheng Jia , Jing Wang , Xin Geng

Although increasingly used as a data resource for assembling cohorts, electronic health records (EHRs) pose many analytic challenges. In particular, a patient's health status influences when and what data are recorded, generating sampling…

Methodology · Statistics 2020-04-28 Yifei Sun , Charles E. McCulloch , Kieren A. Marr , Chiung-Yu Huang

A brain computer interface (BCI) is a system which provides direct communication between the mind of a person and the outside world by using only brain activity (EEG). The event-related potential (ERP)-based BCI problem consists of a binary…

Computer Vision and Pattern Recognition · Computer Science 2016-08-25 Victoria Peterson , Hugo Leonardo Rufiner , Ruben Daniel Spies

The performance of machine learning and pattern recognition algorithms generally depends on data representation. That is why, much of the current effort in performing machine learning algorithms goes into the design of preprocessing…

Machine Learning · Computer Science 2025-10-28 Fadi Dornaika , Ahmad Khoder , Abdelmalik Moujahid , Wassim Khoder

Classification of high-dimensional low sample size (HDLSS) data poses a challenge in a variety of real-world situations, such as gene expression studies, cancer research, and medical imaging. This article presents the development and…

Machine Learning · Statistics 2026-05-27 Jyotishka Ray Choudhury , Aytijhya Saha , Sarbojit Roy , Subhajit Dutta

The rapid expansion of large-scale electronic health record (EHR) data offers unique opportunities to improve the accuracy and efficiency of clinical risk estimation. Yet, because clinical events may occur outside the recording health…

Methodology · Statistics 2026-05-11 Jie Zhou , Enhao Wang , Xuan Wang

Long-tailed semi-supervised learning (LTSSL) represents a practical scenario for semi-supervised applications, challenged by skewed labeled distributions that bias classifiers. This problem is often aggravated by discrepancies between…

Machine Learning · Computer Science 2024-07-16 Emanuel Sanchez Aimar , Nathaniel Helgesen , Yonghao Xu , Marco Kuhlmann , Michael Felsberg

In this paper, we propose a novel approach named by Discriminative Principal Component Analysis which is abbreviated as Discriminative PCA in order to enhance separability of PCA by Linear Discriminant Analysis (LDA). The proposed method…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Hanli Qiao

Early prediction of Alzheimer's disease (AD) is crucial for timely intervention and treatment. This study aims to use machine learning approaches to analyze longitudinal electronic health records (EHRs) of patients with AD and identify…

Machine Learning · Computer Science 2025-04-29 Rumeng Li , Xun Wang , Dan Berlowitz , Brian Silver , Wen Hu , Heather Keating , Raelene Goodwin , Weisong Liu , Honghuang Lin , Hong Yu

Health risk prediction is one of the fundamental tasks under predictive modeling in the medical domain, which aims to forecast the potential health risks that patients may face in the future using their historical Electronic Health Records…

Machine Learning · Computer Science 2023-10-09 Yuan Zhong , Suhan Cui , Jiaqi Wang , Xiaochen Wang , Ziyi Yin , Yaqing Wang , Houping Xiao , Mengdi Huai , Ting Wang , Fenglong Ma

Tabular data have been playing a vital role in diverse real-world fields, including healthcare, finance, etc. With the recent success of Large Language Models (LLMs), early explorations of extending LLMs to the domain of tabular data have…

Machine Learning · Computer Science 2025-12-11 Hangting Ye , Jinmeng Li , He Zhao , Dandan Guo , Yi Chang

Fisher discriminant analysis (FDA) is a widely used method for classification and dimensionality reduction. When the number of predictor variables greatly exceeds the number of observations, one of the alternatives for conventional FDA is…

Machine Learning · Statistics 2018-11-30 Agniva Chowdhury , Jiasen Yang , Petros Drineas

The use of quadratic discriminant analysis (QDA) or its regularized version (R-QDA) for classification is often not recommended, due to its well-acknowledged high sensitivity to the estimation noise of the covariance matrix. This becomes…

Machine Learning · Statistics 2020-09-15 Amine Bejaoui , Khalil Elkhalil , Abla Kammoun , Mohamed Slim Alouni , Tarek Al-Naffouri

Disease classification relying solely on imaging data attracts great interest in medical image analysis. Current models could be further improved, however, by also employing Electronic Health Records (EHRs), which contain rich information…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Tom van Sonsbeek , Xiantong Zhen , Marcel Worring , Ling Shao

Distributional alignment enables large language models (LLMs) to predict how a target population distributes its responses across answer options, rather than collapsing disagreement into a single consensus answer. However, existing…

Machine Learning · Computer Science 2026-03-17 Viet-Thanh Pham , Lizhen Qu , Zhuang Li , Gholamreza Haffari

Large language models (LLMs) are increasingly used to extract clinical data from electronic health records (EHRs), offering significant improvements in scalability and efficiency for real-world data (RWD) curation in oncology. However, the…