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Modern data workflows are inherently adaptive, repeatedly querying the same dataset to refine and validate sequential decisions, but such adaptivity can lead to overfitting and invalid statistical inference. Adaptive Data Analysis (ADA)…
Machine learning holds great promise for advancing the field of medicine, with electronic health records (EHRs) serving as a primary data source. However, EHRs are often sparse and contain missing data due to various challenges and…
Semi-supervised regression (SSR), which aims to predict continuous scores for samples while reducing the reliance on large-scale labeled data, has recently attracted considerable attention across various applications, including computer…
In recent years, increasingly augmentation of health data, such as patient Electronic Health Records (EHR), are becoming readily available. This provides an unprecedented opportunity for knowledge discovery and data mining algorithms to dig…
Recognizing images with long-tailed distributions remains a challenging problem while there lacks an interpretable mechanism to solve this problem. In this study, we formulate Long-tailed recognition as Domain Adaption (LDA), by modeling…
Instruction tuning is critical for adapting large language models (LLMs) to downstream tasks, and recent studies have demonstrated that small amounts of human-curated data can outperform larger datasets, challenging traditional data scaling…
Human Activity Recognition (HAR) has seen significant advancements with the adoption of deep learning techniques, yet challenges remain in terms of data requirements, reliability and robustness. This paper explores a novel application of…
Fall risk prediction among hospitalized patients is a critical aspect of patient safety in clinical settings, and accurate models can help prevent adverse events. The Hester Davis Score (HDS) is commonly used to assess fall risk, with…
Globally, chronic liver disease continues to be a major health concern that requires precise predictive models for prompt detection and treatment. Using the Indian Liver Patient Dataset (ILPD) from the University of California at Irvine's…
Heart disease is one of the significant challenges in today's world and one of the leading causes of many deaths worldwide. Recent advancement of machine learning (ML) application demonstrates that using electrocardiogram (ECG) and patient…
Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A…
Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality. Constructing predictive statistical models typically requires extraction of curated predictor…
Recent advances in Large Language Models (LLMs) have led to remarkable progresses in medical consultation. However, existing medical LLMs overlook the essential role of Electronic Health Records (EHR) and focus primarily on diagnosis…
How to improve discriminative feature learning is central in classification. Existing works address this problem by explicitly increasing inter-class separability and intra-class similarity, whether by constructing positive and negative…
Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…
Kernel alignment measures the degree of similarity between two kernels. In this paper, inspired from kernel alignment, we propose a new Linear Discriminant Analysis (LDA) formulation, kernel alignment LDA (kaLDA). We first define two…
Hierarchical latent tree analysis (HLTA) is recently proposed as a new method for topic detection. It differs fundamentally from the LDA-based methods in terms of topic definition, topic-document relationship, and learning method. It has…
Local differential privacy (LDP) has become a central topic in data privacy research, offering strong privacy guarantees by perturbing user data at the source and removing the need for a trusted curator. However, the noise introduced by LDP…
The allostatic load index (ALI) is a 10-component measure of whole-person health. Data from electronic health records (EHR) present a huge opportunity to operationalize the ALI in learning health systems; however, these data are prone to…
High-dimensional and incomplete (HDI) matrix contains many complex interactions between numerous nodes. A stochastic gradient descent (SGD)-based latent factor analysis (LFA) model is remarkably effective in extracting valuable information…