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In this work, we study a matrix-valued Allen-Cahn equation with a Saint Venant-Kirchhoff potential $F(\mathbf{A})=\frac{1}{4}\|\mathbf{A}\mathbf{A}^\top-\mathbf{I}\|^2$. Our approach employs the modulated energy method together with weak…

Analysis of PDEs · Mathematics 2026-02-13 Xingyu Wang

We investigate the singular limit, as $\ep \to 0$, of the Fisher equation $\partial_t u=\ep \Delta u + \ep ^{-1}u(1-u)$ in the whole space. We consider initial data with compact support plus perturbations with {\it slow exponential decay}.…

Analysis of PDEs · Mathematics 2010-04-13 Matthieu Alfaro , Arnaud Ducrot

A vectorial Modica--Mortola functional is considered and the convergence to a sharp interface model is studied. The novelty of the paper is that the wells of the potential are not constant, but depend on the spatial position in the domain…

Analysis of PDEs · Mathematics 2020-02-25 Riccardo Cristoferi , Giovanni Gravina

We investigate the long-time dynamics and optimal control problem of a diffuse interface model that describes the growth of a tumor in presence of a nutrient and surrounded by host tissues. The state system consists of a Cahn-Hilliard type…

Analysis of PDEs · Mathematics 2023-07-28 Cecilia Cavaterra , Elisabetta Rocca , Hao Wu

We consider very weak solutions of the Cauchy problem for the porous medium equation on Cartan-Hadamard manifolds, that are assumed to satisfy general curvature bounds and to be stochastically complete. We identify a class of initial data…

Analysis of PDEs · Mathematics 2022-02-18 Gabriele Grillo , Matteo Muratori , Fabio Punzo

In this paper, a distributed optimal control problem is studied for a diffuse interface model of tumor growth which was proposed in [A. Hawkins-Daruud, K.G. van der Zee, J.T. Oden, Numerical simulation of a thermodynamically consistent…

Analysis of PDEs · Mathematics 2018-09-10 Pierluigi Colli , Gianni Gilardi , Elisabetta Rocca , Jürgen Sprekels

We consider a diffuse-interface model for two-phase incompressible viscous flows with a soluble surfactant in a bounded porous medium. This hydrodynamic system consists of a Darcy--Forchheimer equation for the seepage velocity…

Analysis of PDEs · Mathematics 2026-03-24 Maurizio Grasselli , Bohan Ouyang , Andrea Poiatti , Hao Wu

The diffuse interface model of Cahn-Hilliard-van der Waals is often used to study various aspects of multi-phase flows such as droplets coalescence and contact line dynamics. The original model of Cahn-Hilliard-van der Waals uses an…

Fluid Dynamics · Physics 2014-08-29 Lionel Hirschberg , Avraham Hirschberg

In this paper, we aim to study the motions of interfaces and coarsening rates governed by the time-fractional Cahn--Hilliard equation (TFCHE). It is observed by many numerical experiments that the microstructure evolution described by the…

Analysis of PDEs · Mathematics 2021-08-24 Tao Tang , Boyi Wang , Jiang Yang

We present a model for cell growth, division and packing under soft constraints that arise from the deformability of the cells as well as of a membrane that encloses them. Our treatment falls within the framework of diffuse interface…

Cell Behavior · Quantitative Biology 2019-01-09 J. Jiang , K. Garikipati , S. Rudraraju

We consider a continuum mechanical model of cell invasion through thin membranes. The model consists of a transmission problem for cell volume fraction complemented with continuity of stresses and mass flux across the surfaces of the…

Tissues and Organs · Quantitative Biology 2019-08-06 Mark A. J. Chaplain , Chiara Giverso , Tommaso Lorenzi , Luigi Preziosi

We investigate existence and uniqueness of solutions of the Cauchy problem for the porous medium equation on a class of Cartan-Hadamard manifolds. We suppose that the radial Ricci curvature, which is everywhere nonpositive as well as…

Analysis of PDEs · Mathematics 2017-12-14 Matteo Muratori , Fabio Punzo

In this work, we analyze a diffuse-interface model for tumor growth, subject to multiplicative white noises, posed on a bounded domain $\mathcal{O} \subset \mathbb{R}^d$, $d=2,3$. The model couples a stochastic incompressible convective…

Analysis of PDEs · Mathematics 2026-05-29 Kalpana Rawat , Kumarasamy Sakthivel

We consider the inverse problem of identifying parameters in a variant of the diffuse interface model for tumour growth model proposed by Garcke, Lam, Sitka and Styles (Math. Models Methods Appl. Sci. 2016). The model contains three…

Optimization and Control · Mathematics 2017-07-24 Christian Kahle , Kei Fong Lam

At the continuous level, we consider two types of tumor growth models: the cell density model, which is based on the fluid mechanical construction, is more favorable for scientific interpretation and numerical simulations; and the free…

Analysis of PDEs · Mathematics 2019-10-28 Jian-Guo Liu , Min Tang , Li Wang , Zhennan Zhou

The effective dilatational and shear viscosities of a particle-laden fluid interface are computed in the dilute limit under the assumption of an asymptotically vanishing viscosity ratio between both fluids. Spherical particles with a given…

Fluid Dynamics · Physics 2020-10-28 Michael Eigenbrod , Steffen Hardt

This paper concerns a diffuse interface model for the flow of two incompressible viscoelastic fluids in a bounded domain. More specifically, the fluids are assumed to be macroscopically immiscible, but with a small transition region, where…

Analysis of PDEs · Mathematics 2024-11-15 Yadong Liu , Dennis Trautwein

We derive a Cahn-Hilliard-Darcy model to describe multiphase tumour growth taking interactions with multiple chemical species into account as well as the simultaneous occurrence of proliferating, quiescent and necrotic regions. Via a…

Analysis of PDEs · Mathematics 2019-11-01 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Emanuel Sitka

We consider a one-dimensional version of a model obtained in [C. Engwer, A. Hunt, and C. Surulescu: Effective equations for anisotropic glioma spread with proliferation: a multiscale approach and comparisons with previous settings, IMA J.…

Analysis of PDEs · Mathematics 2025-11-04 Michael Winkler , Christina Surulescu

A distributed optimal control problem for a phase field system which physical context is that of tumor growth is discussed. The system we are going to take into account consists of a Cahn-Hilliard equation for the phase variable (relative…

Analysis of PDEs · Mathematics 2021-01-20 Andrea Signori