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Cone beam computed tomography (CBCT) images can be used for dose calculation in adaptive radiation therapy (ART). The main challenges are the large artefacts and inaccurate Hounsfield unit (HU) values. Currently, deformed planning CT images…

Medical Physics · Physics 2019-09-04 Xiao Liang , Liyuan Chen , Dan Nguyen , Zhiguo Zhou , Xuejun Gu , Ming Yang , Jing Wang , Steve Jiang

Purpose: Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. The authors have investigated a photon-counting spectral…

Medical Physics · Physics 2021-01-21 Erik Fredenberg , Magnus Hemmendorff , Bjorn Cederstrom , Magnus Aslund , Mats Danielsson

Purpose: Developing photon-counting CT detectors requires understanding the impact of parameters such as converter material, absorption length and pixel size. We apply a novel linear-systems framework, incorporating spatial and energy…

Medical Physics · Physics 2020-03-03 Mats Persson , Adam Wang , Norbert J. Pelc

Charged particle beams are used in Particle Therapy (PT) to treat oncological patients due to their selective dose deposition in tissues and to their high biological effect in killing cancer cells with respect to photons and electrons used…

Computer-Assisted Interventions enable clinicians to perform precise, minimally invasive procedures, often relying on advanced imaging methods. Cone-beam computed tomography (CBCT) can be used to facilitate computer-assisted interventions,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-04 Maximilian E. Tschuchnig , Philipp Steininger , Michael Gadermayr

This study aimed to propose a denoising method for dynamic contrast-enhanced computed tomography (DCE-CT) perfusion studies using a three-dimensional deep image prior (DIP), and to investigate its usefulness in comparison with total…

Medical Physics · Physics 2023-04-04 Kenya Murase

We demonstrate that in situ coherent diffractive imaging (CDI), which harnesses the coherent interference between a strong and a weak beam illuminating a static and dynamic structure, can be a very dose-efficient imaging method. At low…

Background: Perfusion computed tomography (CT) images the dynamics of a contrast agent through the body over time, and is one of the highest X-ray dose scans in medical imaging. Recently, a theoretically justified reconstruction algorithm…

Medical Physics · Physics 2026-02-04 Namhoon Kim , Ashwin Pananjady , Amir Pourmorteza , Sara Fridovich-Keil

Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…

Low x-ray dose is desirable in x-ray computed tomographic (CT) imaging due to health concerns. But low dose comes with a cost of low signal artifacts such as streaks and low frequency bias in the reconstruction. As a result, low signal…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Obaidullah Rahman , Ken D. Sauer , Charles A. Bouman , Roman Melnyk , Brian Nett

Diffusion models have significant impact on wide range of generative tasks, especially on image inpainting and restoration. Although the improvements on aiming for decreasing number of function evaluations (NFE), the iterative results are…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Mahmut S. Gokmen , Jie Zhang , Ge Wang , Jin Chen , Cody Bumgardner

The dark photon is a new hypothetical gauge boson arising in extensions of the Standard Model, and constitutes a compelling dark matter candidate. As dark photon dark matter (DPDM), it can interact with electromagnetic fields via kinetic…

High Energy Astrophysical Phenomena · Physics 2026-02-26 Júlia G. Mamprim , Aion Viana , Vitor de Souza

Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition. Based on dual-energy material decomposition, the…

Medical Physics · Physics 2016-11-15 Wei Zhao , Lu Wan , Bo Zhang , Qiude Zhang , Tianye Niu

Cone-beam computed tomography (CBCT) images are problematic in clinical medicine because of their low contrast and high artifact content compared with conventional CT images. Although there are some studies to improve image quality, in…

Image and Video Processing · Electrical Eng. & Systems 2026-03-30 Naruki Murahashi , Mitsuhiro Nakamura , Megumi Nakao

This paper proposes a novel and fast self-supervised solution for sparse-view CBCT reconstruction (Cone Beam Computed Tomography) that requires no external training data. Specifically, the desired attenuation coefficients are represented as…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Ruyi Zha , Yanhao Zhang , Hongdong Li

In clinical examinations and diagnoses, low-dose computed tomography (LDCT) is crucial for minimizing health risks compared with normal-dose computed tomography (NDCT). However, reducing the radiation dose compromises the signal-to-noise…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Haoyu Zhao , Yuliang Gu , Zhou Zhao , Bo Du , Yongchao Xu , Rui Yu

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

Medical Physics · Physics 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu

Objective: To propose a CBCT dose optimization method using readily available measurement equipment in radiation oncology departments. Approach: A 0.6cc air kerma (Kair) calibrated Farmer chamber measured Kair at isocenter for five default…

Medical Physics · Physics 2025-02-04 S. Gros , J. Bian , J. Jackson , M. Delafuente , H. Kang , W. Small , M. Mahesh

In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is, therefore, challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable…

Medical Physics · Physics 2019-11-01 Wei Zhao , Tianling Lv , Peng Gao , Liyue Shen , Xianjin Dai , Kai Cheng , Mengyu Jia , Yang Chen , Lei Xing

Photoacoustic imaging (PAI) is a promising medical imaging modality providing the spatial resolution of ultrasound (US) imaging and the contrast of pure optical imaging. For linear-array PAI, a beamformer has to be used as the…

Medical Physics · Physics 2018-02-15 Moein Mozaffarzadeh , Yan Yan , Mohammad Mehrmohammadi , Bahador Makkiabadi
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