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In this thesis, we present robust and fully-automated methods for the subdivision of the entire human cerebral cortex based on connectivity information. Our contributions are four-fold: First, we propose a clustering approach to delineate a…

Neurons and Cognition · Quantitative Biology 2018-02-21 Salim Arslan

One of the primary objectives of human brain mapping is the division of the cortical surface into functionally distinct regions, i.e. parcellation. While it is generally agreed that at macro-scale different regions of the cortex have…

Neurons and Cognition · Quantitative Biology 2017-03-06 Daniel Moyer , Boris A Gutman , Neda Jahanshad , Paul M. Thompson

Brain atlases are a ubiquitous tool used for analyzing and interpreting brain imaging datasets. Traditionally, brain atlases divided the brain into regions separated by anatomical landmarks. In the last decade, several attempts have been…

Quantitative Methods · Quantitative Biology 2018-02-08 Pantea Moghimi , Kelvin O. Lim , Theoden I. Netoff

Brain parcellations play a ubiquitous role in the analysis of magnetic resonance imaging (MRI) datasets. Over 100 years of research has been conducted in pursuit of an ideal brain parcellation. Different methods have been developed and…

Neurons and Cognition · Quantitative Biology 2021-07-09 Pantea Moghimi , Anh The Dang , Theoden I. Netoff , Kelvin O. Lim , Gowtham Atluri

We take an image science perspective on the problem of determining brain network connectivity given functional activity. But adapting the concept of image resolution to this problem, we provide a new perspective on network partitioning for…

Neurons and Cognition · Quantitative Biology 2020-02-14 Keith Dillon , Yu-Ping Wang

Microscopic analysis of histological sections is considered the "gold standard" to verify structural parcellations in the human brain. Its high resolution allows the study of laminar and columnar patterns of cell distributions, which build…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Hannah Spitzer , Katrin Amunts , Stefan Harmeling , Timo Dickscheid

The study of hierarchy in networks of the human brain has been of significant interest among the researchers as numerous studies have pointed out towards a functional hierarchical organization of the human brain. This paper provides a novel…

Neurons and Cognition · Quantitative Biology 2021-03-02 Dushyant Sahoo , Theodore D. Satterthwaite , Christos Davatzikos

Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

Computational Engineering, Finance, and Science · Computer Science 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

We present a hybrid method that performs the complete parcellation of the cerebral cortex of an individual, based on the connectivity information of the white matter fibers from a whole-brain tractography dataset. The method consists of…

Neurons and Cognition · Quantitative Biology 2020-02-24 Narciso López-López , Andrea Vázquez , Cyril Poupon , Jean-François Mangin , Pamela Guevara

Current theories hold that brain function is highly related to long-range physical connections through axonal bundles, namely extrinsic connectiv-ity. However, obtaining a groupwise cortical parcellation based on extrinsic connectivity…

Applications · Statistics 2017-01-06 Guillermo Gallardo , William Wells , Rachid Deriche , Demian Wassermann

Cytoarchitectonic parcellations of the human brain serve as anatomical references in multimodal atlas frameworks. They are based on analysis of cell-body stained histological sections and the identification of borders between brain areas.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Hannah Spitzer , Kai Kiwitz , Katrin Amunts , Stefan Harmeling , Timo Dickscheid

Cytoarchitectonic mapping provides anatomically grounded parcellations of brain structure and forms a foundation for integrative, multi-modal neuroscience analyses. These parcellations are defined based on the shape, density, and spatial…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Shiqi Zhang , Fang Xu , Pengcheng Zhou

We present cortical surface parcellation using spherical deep convolutional neural networks. Traditional multi-atlas cortical surface parcellation requires inter-subject surface registration using geometric features with high processing…

Individual brains vary greatly in morphology, connectivity and organization. The applicability of group-level parcellations is limited by the rapid development of precision medicine today because they do not take into account the variation…

Neurons and Cognition · Quantitative Biology 2024-07-02 Chengyi Li , Shan Yu , Yue Cui

A large number of surface-based analyses on brain imaging data adopt some specific brain atlases to better assess structural and functional changes in one or more brain regions. In these analyses, it is necessary to obtain an anatomically…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Wen Zhang , Yalin Wang

The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD). Moreover, for a…

Neurons and Cognition · Quantitative Biology 2022-10-05 Anne-Marie Rickmann , Fabian Bongratz , Sebastian Pölsterl , Ignacio Sarasua , Christian Wachinger

Many atlases used for brain parcellation are hierarchically organised, progressively dividing the brain into smaller sub-regions. However, state-of-the-art parcellation methods tend to ignore this structure and treat labels as if they are…

Computer Vision and Pattern Recognition · Computer Science 2020-09-17 Mark S. Graham , Carole H. Sudre , Thomas Varsavsky , Petru-Daniel Tudosiu , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

Cortical surface parcellation is a fundamental task in both basic neuroscience research and clinical applications, enabling more accurate mapping of brain regions. Model-based and learning-based approaches for automated parcellation…

Neurons and Cognition · Quantitative Biology 2025-12-30 Jian Li , Karthik Gopinath , Brian L. Edlow , Adrian V. Dalca , Bruce Fischl

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Functional Magnetic Resonance Images acquired during resting-state provide information about the functional organization of the brain through measuring correlations between brain areas. Independent components analysis is the reference…

Neurons and Cognition · Quantitative Biology 2014-12-15 Alexandre Abraham , Elvis Dohmatob , Bertrand Thirion , Dimitris Samaras , Gael Varoquaux
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