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We present a novel topological framework for analyzing functional brain signals using time-frequency analysis. By integrating persistent homology with time-frequency representations, we capture multi-scale topological features that…

Neurons and Cognition · Quantitative Biology 2025-04-23 Moo K. Chung , Aaron F. Struck

Whole-brain tractography in diffusion MRI is often followed by a parcellation in which each streamline is classified as belonging to a specific white matter bundle, or discarded as a false positive. Efficient parcellation is important both…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Valentin von Bornhaupt , Johannes Grün , and Justus Bisten , Tobias Bauer , Theodor Rüber , Thomas Schultz

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

Different brain imaging modalities offer unique insights into brain function and structure. Combining them enhances our understanding of neural mechanisms. Prior multimodal studies fusing functional MRI (fMRI) and structural MRI (sMRI) have…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Oktay Agcaoglu , Rogers F. Silva , Deniz Alacam , Sergey Plis , Tulay Adali , Vince Calhoun

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

Applications · Statistics 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

Recent deep learning approaches have shown promise in learning such individual brain parcellations from functional magnetic resonance imaging (fMRI). However, most existing methods assume consistent data distributions across domains and…

Artificial Intelligence · Computer Science 2025-07-30 Jianfei Zhu , Haiqi Zhu , Shaohui Liu , Feng Jiang , Baichun Wei , Chunzhi Yi

In recent years, deep learning models have become ubiquitous in industry and academia alike. Deep neural networks can solve some of the most complex pattern-recognition problems today, but come with the price of massive compute and memory…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-24 Shreshth Tuli , Giuliano Casale , Nicholas R. Jennings

This study introduces the Iterative Chainlet Partitioning (ICP) algorithm and its neural acceleration for solving the Traveling Salesman Problem with Drone (TSP-D). The proposed ICP algorithm decomposes a TSP-D solution into smaller…

Neural and Evolutionary Computing · Computer Science 2025-09-25 Jae Hyeok Lee , Minwoo Kim , Minjun Kim , Jinkyoo Park , Changhyun Kwon

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

Neurons and Cognition · Quantitative Biology 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

This paper introduces a novel methodology to integrate human brain connectomics and parcellation for brain tumor segmentation and survival prediction. For segmentation, we utilize an existing brain parcellation atlas in the MNI152 1mm space…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Po-Yu Kao , Thuyen Ngo , Angela Zhang , Jefferson W. Chen , B. S. Manjunath

Whole brain parcellation requires inferring hundreds of segmentation labels in large image volumes and thus presents significant practical challenges for deep learning approaches. We introduce label merge-and-split, a method that first…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Aaron Kujawa , Reuben Dorent , Sebastien Ourselin , Tom Vercauteren

Regionalization aims to partition a spatial domain into contiguous regions that share similar characteristics, enabling more effective spatial analysis, policy making, and resource management. Existing approaches for spatial regionalization…

Machine Learning · Statistics 2026-05-07 Jiayu Weng , Alec Kirkley

Parcellation of whole-brain tractography streamlines is an important step for tract-based analysis of brain white matter microstructure. Existing fiber parcellation approaches rely on accurate registration between an atlas and the…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Feihong Liu , Jun Feng , Geng Chen , Ye Wu , Yoonmi Hong , Pew-Thian Yap , Dinggang Shen

In-memory computing is an emerging computing paradigm that could enable deeplearning inference at significantly higher energy efficiency and reduced latency. The essential idea is to map the synaptic weights corresponding to each layer to…

Machine Learning · Computer Science 2019-06-11 Martino Dazzi , Abu Sebastian , Pier Andrea Francese , Thomas Parnell , Luca Benini , Evangelos Eleftheriou

Brain decoding, aiming to identify the brain states using neural activity, is important for cognitive neuroscience and neural engineering. However, existing machine learning methods for fMRI-based brain decoding either suffer from low…

Neurons and Cognition · Quantitative Biology 2022-10-13 Ziyuan Ye , Youzhi Qu , Zhichao Liang , Mo Wang , Quanying Liu

In this paper, we propose a simple but effective method for fast image segmentation. We re-examine the locality-preserving character of spectral clustering by constructing a graph over image regions with both global and local connections.…

Computer Vision and Pattern Recognition · Computer Science 2017-12-05 Zizhao Zhang , Fuyong Xing , Hanzi Wang , Yan Yan , Ying Huang , Xiaoshuang Shi , Lin Yang

The amygdala plays a vital role in emotional processing and exhibits structural diversity that necessitates fine-scale parcellation for a comprehensive understanding of its anatomico-functional correlations. Diffusion MRI tractography is an…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Haolin He , Ce Zhu , Le Zhang , Yipeng Liu , Xiao Xu , Yuqian Chen , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Lauren J. O'Donnell , Fan Zhang

The main goal of this study is to extract a set of brain networks in multiple time-resolutions to analyze the connectivity patterns among the anatomic regions for a given cognitive task. We suggest a deep architecture which learns the…

Machine Learning · Statistics 2017-08-16 Arash Rahnama , Abdullah Alchihabi , Vijay Gupta , Panos Antsaklis , Fatos T. Yarman Vural

Deep convolutional neural networks are powerful tools for learning visual representations from images. However, designing efficient deep architectures to analyse volumetric medical images remains challenging. This work investigates…

Computer Vision and Pattern Recognition · Computer Science 2017-07-10 Wenqi Li , Guotai Wang , Lucas Fidon , Sebastien Ourselin , M. Jorge Cardoso , Tom Vercauteren