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The human connectome represents a network map of the brain's wiring diagram and the pattern into which its connections are organized is thought to play an important role in cognitive function. The generative rules that shape the topology of…

The human connectome has become the very frequent subject of study of brain-scientists, psychologists, and imaging experts in the last decade. With diffusion magnetic resonance imaging techniques, unified with advanced data processing…

Neurons and Cognition · Quantitative Biology 2019-07-24 Mate Fellner , Balint Varga , Vince Grolmusz

This paper proposes that two distinct types of structures are present in the brain: Symbolic Knowledge Structures (SKSs), used for formal symbolic reasoning, and Intuitive Knowledge Structures (IKSs), used for drawing informal associations.…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-08 Nancy Lynch

Cognitive neuroscience explores the mechanisms of cognition by studying its structural and functional brain correlates. Here, we report the first systematic review that assesses how information from structural and functional neuroimaging…

Neurons and Cognition · Quantitative Biology 2022-02-07 Marta Czime Litwińczuk , Nelson Trujillo-Barreto , Nils Muhlert , Lauren Cloutman , Anna Woollams

Brain decoding involves the determination of a subject's cognitive state or an associated stimulus from functional neuroimaging data measuring brain activity. In this setting the cognitive state is typically characterized by an element of a…

Machine Learning · Statistics 2015-04-14 Nicole Croteau , Farouk S. Nathoo , Jiguo Cao , Ryan Budney

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…

Computation · Statistics 2023-08-11 William Consagra , Martin Cole , Xing Qiu , Zhengwu Zhang

Brain networks, graphical models such as those constructed from MRI, have been widely used in pathological prediction and analysis of brain functions. Within the complex brain system, differences in neuronal connection strengths parcellate…

Machine Learning · Computer Science 2023-05-09 Wei Dai , Hejie Cui , Xuan Kan , Ying Guo , Sanne van Rooij , Carl Yang

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza

The cerebral cortex is composed of multiple cortical areas that exert a wide variety of brain functions. Although human brain neurons are genetically and areally mosaic, the three-dimensional structural differences between neurons in…

The brain is a highly complex organ consisting of a myriad of subsystems that flexibly interact and adapt over time and context to enable perception, cognition, and behavior. Understanding the multi-scale nature of the brain, i.e., how…

Neurons and Cognition · Quantitative Biology 2025-01-17 Adam S. Charles

The human brain is the most complex object of study we encounter today. Mapping the neuronal-level connections between the more than 80 billion neurons in the brain is a hopeless task for science. By the recent advancement of magnetic…

Neurons and Cognition · Quantitative Biology 2020-09-01 Balint Varga , Vince Grolmusz

In this paper, the branches of recursive and recurrent neural networks are classified in detail according to the network structure, training objective function and learning algorithm implementation. They are roughly divided into three…

Neural and Evolutionary Computing · Computer Science 2025-10-22 Jian-wei Liu , Bing-rong Xu , Zhi-yan Song

Spatial navigation in mammals is based on building a mental representation of their environment---a cognitive map. However, both the nature of this cognitive map and its underpinning in neural structures and activity remains vague. A key…

Neurons and Cognition · Quantitative Biology 2016-03-22 A. Babichev , S. Cheng , Yu. Dabaghian

In systems neuroscience, most models posit that brain regions communicate information under constraints of efficiency. Yet, evidence for efficient communication in structural brain networks characterized by hierarchical organization and…

Studying the cellular architecture of the human cerebral cortex is critical for understanding brain organization and function. It requires investigating complex texture patterns in histological images, yet automatic methods that scale…

Neurons and Cognition · Quantitative Biology 2026-03-06 Christian Schiffer , Zeynep Boztoprak , Jan-Oliver Kropp , Julia Thönnißen , Katia Berr , Hannah Spitzer , Katrin Amunts , Timo Dickscheid

A recent publication provides the network graph for a neocortical microcircuit comprising 8 million connections between 31,000 neurons (H. Markram, et al., Reconstruction and simulation of neocortical microcircuitry, Cell, 163 (2015) no. 2,…

Neurons and Cognition · Quantitative Biology 2017-06-13 Pawe Dotko , Kathryn Hess , Ran Levi , Max Nolte , Michael Reimann , Martina Scolamiero , Katharine Turner , Eilif Muller , Henry Markram

Here we show a method of directing the edges of the connectomes, prepared from diffusion tensor imaging (DTI) datasets from the human brain. Before the present work, no high-definition directed braingraphs (or connectomes) were published,…

Neurons and Cognition · Quantitative Biology 2016-09-29 Balázs Szalkai , Csaba Kerepesi , Bálint Varga , Vince Grolmusz

A wide range of networked systems exhibit highly connected nodes (hubs) as prominent structural elements. The functional roles of hubs in the collective nonlinear dynamics of many such networks, however, are not well understood. Here we…

Biological Physics · Physics 2014-03-26 Sven Jahnke , Raoul-Martin Memmesheimer , Marc Timme

Graph embedding is a powerful method to represent graph neurological data (e.g., brain connectomes) in a low dimensional space for brain connectivity mapping, prediction and classification. However, existing embedding algorithms have two…

Computer Vision and Pattern Recognition · Computer Science 2020-09-25 Alin Banka , Inis Buzi , Islem Rekik

Investigation of the neural basis of self-generated thought is moving beyond a simple identification with default network activation toward a more comprehensive view recognizing the role of the frontoparietal control network and other…

Neurons and Cognition · Quantitative Biology 2016-07-06 Kieran C. R. Fox , Jessica R. Andrews-Hanna , Kalina Christoff