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The contribution of structural connectivity to functional brain states remains poorly understood. We present a mathematical and computational study suited to assess the structure--function issue, treating a system of Jansen--Rit neural-mass…

Neurons and Cognition · Quantitative Biology 2020-07-10 Michael Forrester , Stephen Coombes , Jonathan J. Crofts , Stamatios N. Sotiropoulos , Reuben D. O'Dea

In recent years, there has been strong interest in neuroscience studies to investigate brain organization through networks of brain regions that demonstrate strong functional connectivity (FC). These networks are extracted from observed…

Applications · Statistics 2017-03-14 Phebe Brenne Kemmer , F. DuBois Bowman , Helen Mayberg , Ying Guo

Recent advances in neuroimaging along with algorithmic innovations in statistical learning from network data offer a unique pathway to integrate brain structure and function, and thus facilitate revealing some of the brain's organizing…

Signal Processing · Electrical Eng. & Systems 2021-12-21 Yang Li , Gonzalo Mateos , Zhengwu Zhang

In the last decade, network science has shed new light both on the structural (anatomical) and on the functional (correlations in the activity) connectivity among the different areas of the human brain. The analysis of brain networks has…

Physics and Society · Physics 2017-04-18 Federico Battiston , Vincenzo Nicosia , Mario Chavez , Vito Latora

Signal propagation along the structural connectome of the brain induces changes in the patterns of activity. These activity patterns define global brain states and contain information in accordance with their expected probability of…

Neurons and Cognition · Quantitative Biology 2023-03-16 Leon Weninger , Pragya Srivastava , Dale Zhou , Jason Z. Kim , Eli J. Cornblath , Maxwell A. Bertolero , Ute Habel , Dorit Merhof , Dani S. Bassett

Human brain anatomy and function display a combination of modular and hierarchical organization, suggesting the importance of both cohesive structures and variable resolutions in the facilitation of healthy cognitive processes. However,…

Neurons and Cognition · Quantitative Biology 2015-06-18 Christian Lohse , Danielle S. Bassett , Kelvin O. Lim , Jean M. Carlson

Decoding the heterogeneity of biological neural systems is key to understanding the nervous system's complex dynamical behaviors. This study analyzes the comprehensive Drosophila brain connectome, which is the most recent data set,…

Neurons and Cognition · Quantitative Biology 2025-10-01 Xiaoyu Zhang , Pengcheng Yang , Yifei Zhang , Bowei Qin , Qiang Luo , Wei Lin , Xin Lu

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Structural connectomes are detailed graphs that map how different brain regions are physically connected, offering critical insight into aging, cognition, and neurodegenerative diseases. However, these connectomes are high-dimensional and…

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Attention networks have proven to be an effective approach for embedding categorical inference within a deep neural network. However, for many tasks we may want to model richer structural dependencies without abandoning end-to-end training.…

Computation and Language · Computer Science 2017-02-17 Yoon Kim , Carl Denton , Luong Hoang , Alexander M. Rush

Understanding the common topological characteristics of the human brain network across a population is central to understanding brain functions. The abstraction of human connectome as a graph has been pivotal in gaining insights on the…

Quantitative Methods · Quantitative Biology 2023-04-26 Soumya Das , D. Vijay Anand , Moo K. Chung

Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…

Neurons and Cognition · Quantitative Biology 2022-05-17 Ivan Y. Tyukin , Alexander N. Gorban , Carlos Calvo , Julia Makarova , Valeri A. Makarov

Cortical neurons exhibit a hierarchy of timescales across brain regions in response to input stimuli, which is thought to be crucial for information processing of different temporal scales. Modeling studies suggest that both intra-regional…

Neurons and Cognition · Quantitative Biology 2024-12-24 Yang Qi , Jiexiang Wang , Weiyang Ding , Gustavo Deco , Viktor Jirsa , Wenlian Lu , Jianfeng Feng

The construction of brain graphs from functional Magnetic Resonance Imaging (fMRI) data plays a crucial role in enabling graph machine learning for neuroimaging. However, current practices often rely on rigid pipelines that overlook…

Machine Learning · Computer Science 2025-08-19 Qinwen Ge , Roza G. Bayrak , Anwar Said , Catie Chang , Xenofon Koutsoukos , Tyler Derr

The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…

Quantitative Methods · Quantitative Biology 2025-11-11 Mohamma Reza Salehi , Ali BashirGonbadi , Hamid Soltanian-Zadeh

We propose a new framework, called Hierarchical Multi-resolution Mesh Networks (HMMNs), which establishes a set of brain networks at multiple time resolutions of fMRI signal to represent the underlying cognitive process. The suggested…

Neural and Evolutionary Computing · Computer Science 2017-01-13 Itir Onal Ertugrul , Mete Ozay , Fatos Tunay Yarman Vural

In recent years, new and important perspectives were introduced in the field of neuroimaging with the emergence of the connectionist approach. In this new context, it is important to know not only which brain areas are activated by a…

Neurons and Cognition · Quantitative Biology 2019-04-17 Jean Faber , Priscila C. Antoneli , Guillem Via , Noemi S. Araújo , Daniel J. L. L. Pinheiro , Esper Cavalheiro

Understanding the relationship between the structure and function of the human brain is one of the most important open questions in Neurosciences. In particular, Resting State Networks (RSN) and more specifically the Default Mode Network…

Neurons and Cognition · Quantitative Biology 2019-06-14 Julio A. Peraza-Goicolea , Eduardo Martínez-Montes , Eduardo Aubert , Pedro A. Valdés-Hernández , Roberto Mulet

The brain is a paradigmatic example of a complex system as its functionality emerges as a global property of local mesoscopic and microscopic interactions. Complex network theory allows to elicit the functional architecture of the brain in…

Neurons and Cognition · Quantitative Biology 2017-01-18 Rossana Mastrandrea , Andrea Gabrielli , Fabrizio Piras , Gianfranco Spalletta , Guido Caldarelli , Tommaso Gili