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In this paper we present a methodology to address the problem of brain tissue deformation referred to as 'brain-shift'. This deformation occurs throughout a neurosurgery intervention and strongly alters the accuracy of the neuronavigation…

Medical Physics · Physics 2007-09-06 Marek Bucki , Claudio Lobos , Yohan Payan

The mechanical characterization of brain tissue at high loading velocities is vital for understanding and modeling Traumatic Brain Injury (TBI). The most severe form of TBI is diffuse axonal injury (DAI) which involves damage to individual…

Biological Physics · Physics 2013-02-19 Badar Rashid , Michel Destrade , Michael Gilchrist

Intracranial hemorrhage, bleeding that occurs inside the cranium, is a serious health problem requiring rapid and often intensive medical treatment. Such a condition is traditionally diagnosed by highly-trained specialists analyzing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Utkarsh Chandra Srivastava , Anshuman Singh , K. Sree Kumar

Skull-stripping methods aim to remove the non-brain tissue from acquisition of brain scans in magnetic resonance (MR) imaging. Although several methods sharing this common purpose have been presented in literature, they all suffer from the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Gabriele Valvano , Nicola Martini , Andrea Leo , Gianmarco Santini , Daniele Della Latta , Emiliano Ricciardi , Dante Chiappino

Extensive research has been carried out for at least 50 years to understand the mechanical properties of brain tissue in order to understand the mechanisms of traumatic brain injury (TBI). The observed large variability in experimental…

Medical Physics · Physics 2013-03-04 Badar Rashid , Michel Destrade , Michael Gilchrist

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

A brain stroke occurs when blood flow to a part of the brain is disrupted, leading to cell death. Traditional stroke diagnosis methods, such as CT scans and MRIs, are costly and time-consuming. This study proposes a weighted voting ensemble…

Machine Learning · Computer Science 2025-04-22 Yao Zhiwan , Reza Zarrab , Jean Dubois

Skullstripping is defined as the task of segmenting brain tissue from a full head magnetic resonance image~(MRI). It is a critical component in neuroimage processing pipelines. Downstream deformable registration and whole brain segmentation…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Amod Jog , P. Ellen Grant , Joseph L. Jacobson , Andre van der Kouwe , Ernesta M. Meintjes , Bruce Fischl , Lilla Zöllei

Skull-stripping is the removal of background and non-brain anatomical features from brain images. While many skull-stripping tools exist, few target pediatric populations. With the emergence of multi-institutional pediatric data acquisition…

Image and Video Processing · Electrical Eng. & Systems 2025-12-05 William Kelley , Nathan Ngo , Adrian V. Dalca , Bruce Fischl , Lilla Zöllei , Malte Hoffmann

There is significant interest in modelling the mechanics and physics of growth of soft biological systems such as tumors and bacterial biofilms. Solid tumors account for more than 85% of cancer mortality and bacterial biofilms account for a…

Soft Condensed Matter · Physics 2024-03-29 Chockalingam Senthilnathan , Tal Cohen

In convolutional neural networks (CNNs), pooling operations play important roles such as dimensionality reduction and deformation compensation. In general, max pooling, which is the most widely used operation for local pooling, is performed…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Takato Otsuzuki , Hideaki Hayashi , Yuchen Zheng , Seiichi Uchida

The brain deformation that occurs during neurosurgery is a serious issue impacting the patient "safety" as well as the invasiveness of the brain surgery. Model-driven compensation is a realistic and efficient solution to solve this problem.…

One of the most important tasks in medical image processing is the brain's whole tumor segmentation. It assists in quicker clinical assessment and early detection of brain tumors, which is crucial for lifesaving treatment procedures of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 Apurva Pandya , Catherine Samuel , Nisargkumar Patel , Vaibhavkumar Patel , Thangarajah Akilan

Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…

Neurons and Cognition · Quantitative Biology 2025-02-13 Xinglin Zeng , Yiran Li , Lin Hua , Ruoxi Lu , Lucas Lemos Franco , Peter Kochunov , Shuo Chen , John A Detre , Ze Wang

Cerebrovascular accident, or commonly known as stroke, is an acute disease with extreme impact on patients and healthcare systems and is the second largest cause of death worldwide. Fast and precise stroke lesion detection and location is…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Chuanlong Li

Motion artifacts caused by prolonged acquisition time are a significant challenge in Magnetic Resonance Imaging (MRI), hindering accurate tissue segmentation. These artifacts appear as blurred images that mimic tissue-like appearances,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Sunyoung Jung , Yoonseok Choi , Mohammed A. Al-masni , Minyoung Jung , Dong-Hyun Kim

Cerebrospinal fluid (CSF) plays a pivotal role in normal functioning of Brain. Intracranial compartments such as blood, brain and CSF are incompressible in nature. Therefore, if a volume imbalance in one of the aforenoted compartments is…

Numerical Analysis · Mathematics 2021-02-22 Muhammad Uzair-Ul-Haq , Ali Ahmed , Zartasha Mustansar , Arslan Shaukat , Lee Margetts , Asim Waris , Faizan Nadeem

It is shown that a Hopfield recurrent neural network exhibits a scaling regime, whose specific exponents depend on the number of parcels used and the decay length of the coupling strength. This scaling regime recovers the picture introduced…

Disordered Systems and Neural Networks · Physics 2025-02-17 Giorgio Gosti , Sauro Succi , Giancarlo Ruocco

Cognitive function requires the coordination of neural activity across many scales, from neurons and circuits to large-scale networks. As such, it is unlikely that an explanatory framework focused upon any single scale will yield a…

Neurons and Cognition · Quantitative Biology 2018-01-19 Luca Cocchi , Leonardo L. Gollo , Andrew Zalesky , Michael Breakspear

Aneurysms are localized bulges of arteries, and they can rupture with fatal consequences. Complex mechanobiological factors preclude in vivo testing to assess the rupture risk of an aneurysm, and size based criteria are often used in…

Medical Physics · Physics 2021-08-26 Masoud Hejazi , A. Srikantha Phani