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Brain morphometry study plays a fundamental role in neuroimaging research. In this work, we propose a novel method for brain surface morphometry analysis based on surface foliation theory. Given brain cortical surfaces with automatically…

Computational Geometry · Computer Science 2018-09-11 Chengfeng Wen , Na Lei , Ming Ma , Xin Qi , Wen Zhang , Yalin Wang , David Xianfeng Gu

Brain extraction or skull stripping of magnetic resonance images (MRI) is an essential step in neuroimaging studies, the accuracy of which can severely affect subsequent image processing procedures. Current automatic brain extraction…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Gengyan Zhao , Fang Liu , Jonathan A. Oler , Mary E. Meyerand , Ned H. Kalin , Rasmus M. Birn

We consider a ubiquitous scenario where a fluctuating, semipermeable vesicle is embedded in solution while enclosing a fixed number of solute particles. The swelling with increasing number of particles or decreasing concentration of the…

Soft Condensed Matter · Physics 2008-08-16 Emir Haleva , Haim Diamant

Craniosynostosis, a condition affecting 1 in 2000 infants, is caused by premature fusing of cranial vault sutures, and manifests itself in abnormal skull growth patterns. Left untreated, the condition may lead to severe developmental…

A novel approach is adopted to model cerebrospinal fluid (CSF) flow in human perivascular spaces (PVSs) surrounding brain-penetrating arteries. It is proposed that the outer PVS boundary oscillates due to brain pulsations and the arterial…

Fluid Dynamics · Physics 2025-10-24 Gregory Holba , James P. Hague , Nigel Hoggard , Marc Pradas

Abnormal cortical folding patterns may be related to neurodevelopmental disorders such as lissencephaly and polymicrogyria. In this context, computational modeling is a powerful tool to provide a better understanding of the early brain…

The growth of abnormal cells in the brain's tissue causes brain tumors. Brain tumors are considered one of the most dangerous disorders in children and adults. It develops quickly, and the patient's survival prospects are slim if not…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Al-Akhir Nayan , Ahamad Nokib Mozumder , Md. Rakibul Haque , Fahim Hossain Sifat , Khan Raqib Mahmud , Abul Kalam Al Azad , Muhammad Golam Kibria

The exterior of the mammalian brain - the cerebral cortex - has a conserved layered structure whose thickness varies little across species. However, selection pressures over evolutionary time scales have led to cortices that have a large…

Biological Physics · Physics 2015-03-13 Tuomas Tallinen , Jun Young Chung , John S. Biggins , L. Mahadevan

We investigate experimentally and model theoretically the mechanical behaviour of brain matter in torsion. Using a strain-controlled rheometer we perform torsion tests on fresh porcine brain samples. We quantify the torque and the normal…

Soft Condensed Matter · Physics 2020-01-06 Valentina Balbi , Antonia Trotta , Michel Destrade , Aisling Ní Annaidh

Spreading depolarization (SD) is a self-propagating wave of near-complete neuronal depolarization that is abundant in a wide range of neurological conditions, including stroke. SD was only recently documented in humans and is now considered…

Mechanical characterization of brain tissue has been investigated extensively by various research groups over the past fifty years. These properties are particularly important for modelling Traumatic Brain Injury (TBI). In this research, we…

Medical Physics · Physics 2013-03-04 Badar Rashid , Michel Destrade , Michael D. Gilchrist

The removal of non-brain signal from magnetic resonance imaging (MRI) data, known as skull-stripping, is an integral component of many neuroimage analysis streams. Despite their abundance, popular classical skull-stripping methods are…

Image and Video Processing · Electrical Eng. & Systems 2022-07-27 Andrew Hoopes , Jocelyn S. Mora , Adrian V. Dalca , Bruce Fischl , Malte Hoffmann

In cases when it is desirable to transport medication through blood vessels, especially when dealing with brain cancer being confronted with the narrow arteries in the brain, the blood-brain barrier makes the medical treatment difficult.…

Fluid Dynamics · Physics 2023-03-27 Iver Brevik

Traumatic brain injury [TBI] has become a signature injury of current military conflicts, with debilitating, costly, and long-lasting effects. Although mechanisms by which head impacts cause TBI have been well-researched, the mechanisms by…

Medical Physics · Physics 2017-03-08 William C. Moss , Michael J. King , Eric G. Blackman

Brain tumor segmentation intends to delineate tumor tissues from healthy brain tissues. The tumor tissues include necrosis, peritumoral edema, and active tumor. In contrast, healthy brain tissues include white matter, gray matter, and…

Image and Video Processing · Electrical Eng. & Systems 2020-06-03 Snehal Rajput , Mehul S Raval

Skull stripping magnetic resonance images (MRI) of the human brain is an important process in many image processing techniques, such as automatic segmentation of brain structures. Numerous methods have been developed to perform this task,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-16 Hjalti Thrastarson , Lotta M. Ellingsen

Mechanical characterization of brain tissue at high loading velocities is crucial for modeling Traumatic Brain Injury (TBI). During severe impact conditions, brain tissue experiences compression, tension and shear. Limited experimental data…

Soft Condensed Matter · Physics 2020-09-03 Badar Rashid , Michel Destrade , Michael D. Gilchrist

Brain midline shift (MLS) is one of the most critical factors to be considered for clinical diagnosis and treatment decision-making for intracranial hemorrhage. Existing computational methods on MLS quantification not only require intensive…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Shizhan Gong , Cheng Chen , Yuqi Gong , Nga Yan Chan , Wenao Ma , Calvin Hoi-Kwan Mak , Jill Abrigo , Qi Dou

Whole-brain surface extraction is an essential topic in medical imaging systems as it provides neurosurgeons with a broader view of surgical planning and abnormality detection. To solve the problem confronted in current deep learning skull…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Heng Fang , Xi Yang , Taichi Kin , Takeo Igarashi

Neuro-oncological surgery is the primary brain cancer treatment, yet it faces challenges with gliomas due to their invasiveness and the need to preserve neurological function. Hence, radical resection is often unfeasible, highlighting the…