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Clustering multivariate binary data is of interest in many scientific fields, including ecology, biomedicine, and social policy. Beyond heuristic clustering algorithms, such data can be modelled using multivariate Bernoulli mixture models.…

Methodology · Statistics 2026-04-24 Luisa Ferrari , Maria Franco Villoria , Garritt L. Page , Alex Laini

Cancer has become one of the most widespread diseases in the world. Specifically, breast cancer is diagnosed more often than any other type of cancer. However, breast cancer patients and their individual tumors are often unique. Identifying…

Quantitative Methods · Quantitative Biology 2016-12-06 Chenzhe Qian

Model-based clustering methods for continuous data are well established and commonly used in a wide range of applications. However, model-based clustering methods for categorical data are less standard. Latent class analysis is a commonly…

Methodology · Statistics 2013-02-20 Isabella Gollini , Thomas Brendan Murphy

We propose a novel "tree-averaging" model that utilizes the ensemble of classification and regression trees (CART). Each constituent tree is estimated with a subset of similar data. We treat this grouping of subsets as Bayesian ensemble…

Machine Learning · Statistics 2014-08-20 Leo L. Duan , John P. Clancy , Rhonda D. Szczesniak

Bi-clustering is a technique that allows for the simultaneous clustering of observations and features in a dataset. This technique is often used in bioinformatics, text mining, and time series analysis. An important advantage of…

Computation · Statistics 2023-02-09 Anastasiia Livochka , Ryan Browne , Sanjeena Subedi

Understanding treatment effect heterogeneity is vital for scientific and policy research. However, identifying and evaluating heterogeneous treatment effects pose significant challenges due to the typically unknown subgroup structure.…

Methodology · Statistics 2024-11-05 Kwangho Kim , Jisu Kim , Larry A. Wasserman , Edward H. Kennedy

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

Genomics · Quantitative Biology 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

A model based clustering procedure for data of mixed type, clustMD, is developed using a latent variable model. It is proposed that a latent variable, following a mixture of Gaussian distributions, generates the observed data of mixed type.…

Methodology · Statistics 2015-11-06 Damien McParland , Isobel Claire Gormley

Quantitative analysis of large-scale data is often complicated by the presence of diverse subgroups, which reduce the accuracy of inferences they make on held-out data. To address the challenge of heterogeneous data analysis, we introduce…

Machine Learning · Computer Science 2021-09-01 Nazanin Alipourfard , Keith Burghardt , Kristina Lerman

Machine learning techniques have been widely used in natural language processing (NLP). However, as revealed by many recent studies, machine learning models often inherit and amplify the societal biases in data. Various metrics have been…

Computation and Language · Computer Science 2020-10-07 Jieyu Zhao , Kai-Wei Chang

Due to the challenge posed by multi-source and heterogeneous data collected from diverse environments, causal relationships among features can exhibit variations influenced by different time spans, regions, or strategies. This diversity…

Machine Learning · Computer Science 2025-02-11 Lu Liu , Yang Tang , Kexuan Zhang , Qiyu Sun

Variation in the evolutionary process across the sites of nucleotide sequence alignments is well established, and is an increasingly pervasive feature of datasets composed of gene regions sampled from multiple loci and/or different genomes.…

Populations and Evolution · Quantitative Biology 2014-09-04 Brian R. Moore , Jim McGuire , Fredrik Ronquist , John P. Huelsenbeck

Clustering based on vibration responses, such as transmissibility functions (TFs), is promising in structural anomaly detection. However, most existing methods struggle to determine the optimal cluster number, handle high-dimensional…

Machine Learning · Computer Science 2025-10-21 Lin-Feng Mei , Wang-Ji Yan

In this work, we study the problem of partitioning a set of graphs into different groups such that the graphs in the same group are similar while the graphs in different groups are dissimilar. This problem was rarely studied previously,…

Machine Learning · Computer Science 2023-02-07 Jinyu Cai , Yi Han , Wenzhong Guo , Jicong Fan

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

Applications · Statistics 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

In binary-transaction data-mining, traditional frequent itemset mining often produces results which are not straightforward to interpret. To overcome this problem, probability models are often used to produce more compact and conclusive…

Machine Learning · Computer Science 2012-09-27 Ruefei He , Jonathan Shapiro

Biclustering is an unsupervised machine-learning approach aiming to cluster rows and columns simultaneously in a data matrix. Several biclustering algorithms have been proposed for handling numeric datasets. However, real-world data mining…

Machine Learning · Computer Science 2024-08-26 Adán José-García , Julie Jacques , Clément Chauvet , Vincent Sobanski , Clarisse Dhaenens

Motivation: Clustering techniques are routinely applied to identify patterns of co-expression in gene expression data. Co-regulation, and involvement of genes in similar cellular function, is subsequently inferred from the clusters which…

Quantitative Methods · Quantitative Biology 2016-06-10 Patrick E. McSharry , Edmund J. Crampin

In this paper, we introduce a novel and interpretable methodology to cluster subjects suffering from cancer, based on features extracted from their biopsies. Contrary to existing approaches, we propose here to capture complex patterns in…

Quantitative Methods · Quantitative Biology 2020-07-07 Yassine El Ouahidi , Matis Feller , Matthieu Talagas , Bastien Pasdeloup

It is often of interest to perform clustering on longitudinal data, yet it is difficult to formulate an intuitive model for which estimation is computationally feasible. We propose a model-based clustering method for clustering objects that…

Methodology · Statistics 2020-05-19 Daniel K. Sewell , Yuguo Chen , William Bernhard , Tracy Sulkin
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