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In the field of population health research, understanding the similarities between geographical areas and quantifying their shared effects on health outcomes is crucial. In this paper, we synthesise a number of existing methods to create a…

Applications · Statistics 2023-11-27 Wala Draidi Areed , Aiden Price , Helen Thompson , Reid Malseed , Kerrie Mengersen

Machine learning and in particular deep learning algorithms are the emerging approaches to data analysis. These techniques have transformed traditional data mining-based analysis radically into a learning-based model in which existing data…

Machine Learning · Computer Science 2020-04-17 Neda Tavakoli , Sima Siami-Namini , Mahdi Adl Khanghah , Fahimeh Mirza Soltani , Akbar Siami Namin

Although there is no shortage of clustering algorithms proposed in the literature, the question of the most relevant strategy for clustering compositional data (i.e., data made up of profiles, whose rows belong to the simplex) remains…

Statistics Theory · Mathematics 2018-05-17 Antoine Godichon-Baggioni , Cathy Maugis-Rabusseau , Andrea Rau

Change-point models deal with ordered data sequences. Their primary goal is to infer the locations where an aspect of the data sequence changes. In this paper, we propose and implement a nonparametric Bayesian model for clustering…

Methodology · Statistics 2025-02-12 Ana Carolina da Cruz , Camila P. E. de Souza

The preclinical stage of many neurodegenerative diseases can span decades before symptoms become apparent. Understanding the sequence of preclinical biomarker changes provides a critical opportunity for early diagnosis and effective…

Methodology · Statistics 2024-06-11 Yizhen Xu , Scott Zeger , Zheyu Wang

Survival analysis studies time-modeling techniques for an event of interest occurring for a population. Survival analysis found widespread applications in healthcare, engineering, and social sciences. However, the data needed to train…

Machine Learning · Computer Science 2023-02-22 Alberto Archetti , Eugenio Lomurno , Francesco Lattari , André Martin , Matteo Matteucci

In medical, social, and behavioral research we often encounter datasets with a multilevel structure and multiple correlated dependent variables. These data are frequently collected from a study population that distinguishes several…

Methodology · Statistics 2023-12-18 Xynthia Kavelaars , Joris Mulder , Maurits Kaptein

Over the last decade, a large variety of clustering algorithms have been developed to detect coregulatory relationships among genes from microarray gene expression data. Model based clustering approaches have emerged as statistically well…

Quantitative Methods · Quantitative Biology 2008-01-15 Anagha Joshi , Yves Van de Peer , Tom Michoel

Rapid technological advances have allowed for molecular profiling across multiple omics domains from a single sample for clinical decision making in many diseases, especially cancer. As tumor development and progression are dynamic…

Methodology · Statistics 2022-02-11 Dongyan Yan , Subharup Guha

Longitudinal gene expression profiles of patients are collected in some clinical studies to monitor disease progression and understand disease etiology. The identification of gene sets that have coordinated changes with relevant clinical…

Methodology · Statistics 2016-09-27 Jiehuan Sun , Jose D. Herazo-Maya , Xiu Huang , Naftali Kaminski , Hongyu Zhao

We propose a novel nonparametric Bayesian approach for meta-analysis with event time outcomes. The model is an extension of linear dependent tail-free processes. The extension includes a modification to facilitate (conditionally) conjugate…

Methodology · Statistics 2024-06-25 Bernardo Flores , Peter Mueller

We begin by reviewing some probabilistic results about the Dirichlet Process and its close relatives, focussing on their implications for statistical modelling and analysis. We then introduce a class of simple mixture models in which…

Methodology · Statistics 2010-03-23 Peter J. Green

Most published studies on the statistical analysis of count data generated by next-generation sequencing technologies have paid surprisingly little attention on cluster analysis. We present a statistical methodology (DGEclust) for…

Quantitative Methods · Quantitative Biology 2015-03-24 Dimitrios V Vavoulis , Margherita Francescatto , Peter Heutink , Julian Gough

Cancer subtyping plays a crucial role in informing prognosis and guiding personalized treatment strategies. However, conventional subtyping approaches often rely on static, biopsy-derived scores that hardly capture the biological…

Methodology · Statistics 2026-03-12 Lara Cavinato , Marco Rocchi , Luca Viganò , Francesca Ieva

We present a technique for clustering categorical data by generating many dissimilarity matrices and averaging over them. We begin by demonstrating our technique on low dimensional categorical data and comparing it to several other…

Machine Learning · Statistics 2017-09-20 Saeid Amiri , Bertrand Clarke , Jennifer Clarke

We propose an effective method to solve the event sequence clustering problems based on a novel Dirichlet mixture model of a special but significant type of point processes --- Hawkes process. In this model, each event sequence belonging to…

Machine Learning · Computer Science 2017-09-22 Hongteng Xu , Hongyuan Zha

Statistical modelling in the presence of data organized in groups is a crucial task in Bayesian statistics. The present paper conceives a mixture model based on a novel family of Bayesian priors designed for multilevel data and obtained by…

Methodology · Statistics 2024-07-01 Alessandro Colombi , Raffaele Argiento , Federico Camerlenghi , Lucia Paci

Microarray data analysis is one of the major area of research in the field computational biology. Numerous techniques like clustering, biclustering are often applied to microarray data to extract meaningful outcomes which play key roles in…

Neural and Evolutionary Computing · Computer Science 2019-09-04 Shubhankar Mohapatra , Moumita Sarkar , Anjali Mohapatra , Bhawani Sankar Biswal

Mixtures of multivariate normal inverse Gaussian (MNIG) distributions can be used to cluster data that exhibit features such as skewness and heavy tails. However, for cluster analysis, using a traditional finite mixture model framework,…

Methodology · Statistics 2020-05-13 Yuan Fang , Dimitris Karlis , Sanjeena Subedi

Finite mixture models have become a popular tool for clustering. Amongst other uses, they have been applied for clustering longitudinal data and clustering high-dimensional data. In the latter case, a latent Gaussian mixture model is…

Methodology · Statistics 2018-04-17 Vanessa S. E. Bierling , Paul D. McNicholas
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