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This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

To reduce the large amount of time spent screening, identifying, and recruiting patients into clinical trials, we need prescreening systems that are able to automate the data extraction and decision-making tasks that are typically relegated…

Computation and Language · Computer Science 2016-09-07 Abhishek Kalyan Adupa , Ravi Prakash Garg , Jessica Corona-Cox , Sanjiv. J. Shah , Siddhartha R. Jonnalagadda

Document-level biomedical concept extraction is the task of identifying biomedical concepts mentioned in a given document. Recent advancements have adapted pre-trained language models for this task. However, the scarcity of domain-specific…

Computation and Language · Computer Science 2024-07-04 Qiwei Shao , Fengran Mo , Jian-Yun Nie

The emerging citation-based QA systems are gaining more attention especially in generative AI search applications. The importance of extracted knowledge provided to these systems is vital from both accuracy (completeness of information) and…

Traditional information retrieval systems rely on keywords to index documents and queries. In such systems, documents are retrieved based on the number of shared keywords with the query. This lexical-focused retrieval leads to inaccurate…

Information Retrieval · Computer Science 2013-03-08 Fatiha Boubekeur , Wassila Azzoug

In the scientific digital libraries, some papers from different research communities can be described by community-dependent keywords even if they share a semantically similar topic. Articles that are not tagged with enough keyword…

Digital Libraries · Computer Science 2018-06-22 Hussein T. Al-Natsheh , Lucie Martinet , Fabrice Muhlenbach , Fabien Rico , Djamel A. Zighed

Current medical question answering systems have difficulty processing long, detailed and informally worded questions submitted by patients, called Consumer Health Questions (CHQs). To address this issue, we introduce a medical question…

Computation and Language · Computer Science 2022-10-03 Khalil Mrini , Harpreet Singh , Franck Dernoncourt , Seunghyun Yoon , Trung Bui , Walter Chang , Emilia Farcas , Ndapa Nakashole

Online recruitment platforms require recommendation methods capable of retrieving relevant job opportunities from large and heterogeneous collections of job postings. Keyword-based search is efficient and interpretable, but it may fail to…

Information Retrieval · Computer Science 2026-05-28 Hussein Al Awad , Khaled Fathi Omar

Medical entity retrieval is an integral component for understanding and communicating information across various health systems. Current approaches tend to work well on specific medical domains but generalize poorly to unseen…

Computation and Language · Computer Science 2021-05-27 Luyang Kong , Christopher Winestock , Parminder Bhatia

Overall, the two main contributions of this work include the application of sentence simplification to association extraction as described above, and the use of distributional semantics for concept extraction. The proposed work on concept…

Computation and Language · Computer Science 2011-09-13 Siddhartha Jonnalagadda

Clinical information extraction (e.g., 2010 i2b2/VA challenge) usually presents tasks of concept recognition, assertion classification, and relation extraction. Jointly modeling the multi-stage tasks in the clinical domain is an…

Computation and Language · Computer Science 2026-03-10 Fei Cheng , Ribeka Tanaka , Sadao Kurohashi

Objective: Medical relations are the core components of medical knowledge graphs that are needed for healthcare artificial intelligence. However, the requirement of expert annotation by conventional algorithm development processes creates a…

Machine Learning · Computer Science 2020-09-09 Yucong Lin , Keming Lu , Yulin Chen , Chuan Hong , Sheng Yu

Content-Based Image Retrieval (CBIR) have shown promising results in the field of medical diagnosis, which aims to provide support to medical professionals (doctor or pathologist). However, the ultimate decision regarding the diagnosis is…

Information Retrieval · Computer Science 2025-07-03 Humberto Giuri , Renato A. Krohling

Citation graphs can be helpful in generating high-quality summaries of scientific papers, where references of a scientific paper and their correlations can provide additional knowledge for contextualising its background and main…

Information Retrieval · Computer Science 2023-02-24 Zheheng Luo , Qianqian Xie , Sophia Ananiadou

Existing medical RAG systems mainly leverage knowledge from medical knowledge bases, neglecting the crucial role of experiential knowledge derived from similar patient cases -- a key component of human clinical reasoning. To bridge this…

Computation and Language · Computer Science 2025-05-27 Yuxing Lu , Gecheng Fu , Wei Wu , Xukai Zhao , Sin Yee Goi , Jinzhuo Wang

In this paper, we investigate how semantic relations between concepts extracted from medical documents can be employed to improve the retrieval of medical literature. Semantic relations explicitly represent relatedness between concepts and…

Information Retrieval · Computer Science 2019-05-06 Maristella Agosti , Giorgio Maria Di Nunzio , Stefano Marchesin , Gianmaria Silvello

With the proliferation of research means and computational methodologies, published biomedical literature is growing exponentially in numbers and volume. Cancer cell lines are frequently used models in biological and medical research that…

Computation and Language · Computer Science 2024-02-13 Ellery Smith , Rahel Paloots , Dimitris Giagkos , Michael Baudis , Kurt Stockinger

Retrieval-augmented generation (RAG) improves large language model reliability by grounding generated responses in external evidence. However, RAG performance depends on the relevance of retrieved passages, the quality of evidence ranking,…

Information Retrieval · Computer Science 2026-05-05 Fariba Afrin Irany , Sampson Akwafuo

Searching patients based on the relevance of their medical records is challenging because of the inherent implicit knowledge within the patients' medical records and queries. Such knowledge is known to the medical practitioners but may be…

Information Retrieval · Computer Science 2017-02-02 Nut Limsopatham , Craig Macdonald , Iadh Ounis

Current medical retrieval benchmarks primarily emphasize lexical or shallow semantic similarity, overlooking the reasoning-intensive demands that are central to clinical decision-making. In practice, physicians often retrieve authoritative…

Information Retrieval · Computer Science 2026-04-07 Xiangxu Zhang , Lei Li , Xiao Zhou , Zheng Liu