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A recently developed upscaling technique, the multicontinuum homogenization method, has gained significant attention for its effectiveness in modeling complex multiscale systems. This method defines multiple continua based on distinct…

Numerical Analysis · Mathematics 2025-12-24 Wei Xie , Viet Ha Hoang , Yin Yang , Yunqing Huang

Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling near-atomic-level visualization of biomolecular assemblies. However, the exponential growth in cryo-EM data throughput and complexity, coupled with diverse…

Quantitative Methods · Quantitative Biology 2026-02-25 Weining Fu , Kai Shu , Kui Xu , Qiangfeng Cliff Zhang

Cryo-electron microscopy (cryo-EM) has revolutionized experimental protein structure determination. Despite advances in high resolution reconstruction, a majority of cryo-EM experiments provide either a single state of the studied…

Change detection in heterogeneous multitemporal satellite images is an emerging topic in remote sensing. In this paper we propose a framework, based on image regression, to perform change detection in heterogeneous multitemporal satellite…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Luigi T. Luppino , Filippo M. Bianchi , Gabriele Moser , Stian N. Anfinsen

With the increasing diversity in material systems, ever-expanding number of analysis techniques, and the large capital costs of next generation instruments the ability to quickly and efficiently collect data in the electron microscope has…

Materials Science · Physics 2022-05-10 Matthew Olszta , Kevin Fiedler

As an intrinsic and fundamental property of big data, data heterogeneity exists in a variety of real-world applications, such as precision medicine, autonomous driving, financial applications, etc. For machine learning algorithms, the…

Machine Learning · Computer Science 2023-04-04 Jiashuo Liu , Jiayun Wu , Bo Li , Peng Cui

Multispectral transmission imaging provides strong benefits for early breast cancer screening. The frame accumulation method addresses the challenge of low grayscale and signal-to-noise ratio resulting from the strong absorption and…

Image and Video Processing · Electrical Eng. & Systems 2024-04-04 Jiatong Li , Gang Li , Nan Su Su Win , Ling Lin

In complex plasmas, the behavior of freely floating micrometer sized particles is studied. The particles can be directly visualized and recorded by digital video cameras. To analyze the dynamics of single particles, reliable algorithms are…

Plasma Physics · Physics 2018-02-14 Daniel P. Mohr , Christina A. Knapek , Peter Huber , Erich Zaehringer

We introduce an efficient video segmentation system for resource-limited edge devices leveraging heterogeneous compute. Specifically, we design network models by searching across multiple dimensions of specifications for the neural…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Jamie Menjay Lin , Siargey Pisarchyk , Juhyun Lee , David Tian , Tingbo Hou , Karthik Raveendran , Raman Sarokin , George Sung , Trent Tolley , Matthias Grundmann

In a lot of scientific problems, there is the need to generate data through the running of an extensive number of experiments. Further, some tasks require constant human intervention. We consider the problem of crack detection in steel…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Chinmay Makarand Pimpalkhare , D. N. Pawaskar

Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Koby Bibas , Gili Weiss-Dicker , Dana Cohen , Noa Cahan , Hayit Greenspan

Cellular Electron Cryo-Tomography (CECT) is a powerful imaging technique for the 3D visualization of cellular structure and organization at submolecular resolution. It enables analyzing the native structures of macromolecular complexes and…

Quantitative Methods · Quantitative Biology 2018-05-16 Chang Liu , Xiangrui Zeng , Ruogu Lin , Xiaodan Liang , Zachary Freyberg , Eric Xing , Min Xu

Heterogeneous computing is the strategy of deploying multiple types of processing elements within a single workflow, and allowing each to perform the tasks to which is best suited. To fully harness the power of heterogeneity, we want to be…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-12-03 Nikolaos Mavrogeorgis

We study the problem of parameter estimation using maximum likelihood for fast/slow systems of stochastic differential equations. Our aim is to shed light on the problem of model/data mismatch at small scales. We consider two classes of…

Statistics Theory · Mathematics 2008-06-20 A. Papavasiliou , G. A. Pavliotis , A. M. Stuart

The latent class model is a widely used mixture model for multivariate discrete data. Besides the existence of qualitatively heterogeneous latent classes, real data often exhibit additional quantitative heterogeneity nested within each…

Methodology · Statistics 2025-01-23 Zhongyuan Lyu , Ling Chen , Yuqi Gu

Determining the three-dimensional structure of proteins and protein complexes at atomic resolution is a fundamental task in structural biology. Over the last decade, remarkable progress has been made using "single particle" cryo-electron…

Numerical Analysis · Mathematics 2017-06-05 Alex Barnett , Leslie Greengard , Andras Pataki , Marina Spivak

The phylogenetic tree construction is to infer the evolutionary relationship between species from the experimental data. However, the experimental data are often imperfect and conflicting each others. Therefore, it is important to extract…

Artificial Intelligence · Computer Science 2007-05-23 Andy Auyeung , Ajith Abraham

Scanning Electron Microscopy (SEM) is pivotal in revealing intricate micro- and nanoscale features across various research fields. However, obtaining high-resolution SEM images presents challenges, including prolonged scanning durations and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Tom Reclik , Setareh Medghalchi , Philipp Schumacher , Maximilian Wollenweber , Talal Al-Samman , Sandra Korte-Kerzel , Ulrich Kerzel

Cryo-electron microscopy (cryo-EM) is a powerful imaging technique for reconstructing three-dimensional molecular structures from noisy tomographic projection images of randomly oriented particles. We introduce a new data fusion framework,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Joe Kileel , Oscar Mickelin , Amit Singer , Sheng Xu

This document provides a brief overview of the recently published report on the design of the Large Hadron Electron Collider (LHeC), which comprises its physics programme, accelerator physics, technology and main detector concepts. The LHeC…

High Energy Physics - Experiment · Physics 2013-01-10 J. L. Abelleira Fernandez , C. Adolphsen , P. Adzic , A. N. Akay , H. Aksakal , J. L. Albacete , B. Allanach , S. Alekhin , P. Allport , V. Andreev , R. B. Appleby , E. Arikan , N. Armesto , G. Azuelos , M. Bai , D. Barber , J. Bartels , O. Behnke , J. Behr , A. S. Belyaev , I. Ben-Zvi , N. Bernard , S. Bertolucci , S. Bettoni , S. Biswal , J. Blümlein , H. Böttcher , A. Bogacz , C. Bracco , J. Bracinik , G. Brandt , H. Braun , S. Brodsky , O. Brüning , E. Bulyak , A. Buniatyan , H. Burkhardt , I. T. Cakir , O. Cakir , R. Calaga , A. Caldwell , V. Cetinkaya , V. Chekelian , E. Ciapala , R. Ciftci , A. K. Ciftci , B. A. Cole , J. C. Collins , O. Dadoun , J. Dainton , A. De. Roeck , D. d'Enterria , P. DiNezza , M. D'Onofrio , A. Dudarev , A. Eide , R. Enberg , E. Eroglu , K. J. Eskola , L. Favart , M. Fitterer , S. Forte , A. Gaddi , P. Gambino , H. García Morales , T. Gehrmann , P. Gladkikh , C. Glasman , A. Glazov , R. Godbole , B. Goddard , T. Greenshaw , A. Guffanti , V. Guzey , C. Gwenlan , T. Han , Y. Hao , F. Haug , W. Herr , A. Hervé , B. J. Holzer , M. Ishitsuka , M. Jacquet , B. Jeanneret , E. Jensen , J. M. Jimenez , J. M. Jowett , H. Jung , H. Karadeniz , D. Kayran , A. Kilic , K. Kimura , R. Klees , M. Klein , U. Klein , T. Kluge , F. Kocak , M. Korostelev , A. Kosmicki , P. Kostka , H. Kowalski , M. Kraemer , G. Kramer , D. Kuchler , M. Kuze , T. Lappi , P. Laycock , E. Levichev , S. Levonian , V. N. Litvinenko , A. Lombardi , J. Maeda , C. Marquet , B. Mellado , K. H. Mess , A. Milanese , J. G. Milhano , S. Moch , I. I. Morozov , Y. Muttoni , S. Myers , S. Nandi , Z. Nergiz , P. R. Newman , T. Omori , J. Osborne , E. Paoloni , Y. Papaphilippou , C. Pascaud , H. Paukkunen , E. Perez , T. Pieloni , E. Pilicer , B. Pire , R. Placakyte , A. Polini , V. Ptitsyn , Y. Pupkov , V. Radescu , S. Raychaudhuri , L. Rinolfi , E. Rizvi , R. Rohini , J. Rojo , S. Russenschuck , M. Sahin , C. A. Salgado , K. Sampei , R. Sassot , E. Sauvan , M. Schaefer , U. Schneekloth , T. Schörner-Sadenius , D. Schulte , A. Senol , A. Seryi , P. Sievers , A. N. Skrinsky , W. Smith , D. South , H. Spiesberger , A. M. Stasto , M. Strikman , M. Sullivan , S. Sultansoy , Y. P. Sun , B. Surrow , L. Szymanowski , P. Taels , I. Tapan , T. Tasci , E. Tassi , H. Ten. Kate , J. Terron , H. Thiesen , L. Thompson , P. Thompson , K. Tokushuku , R. Tomás García , D. Tommasini , D. Trbojevic , N. Tsoupas , J. Tuckmantel , S. Turkoz , T. N. Trinh , K. Tywoniuk , G. Unel , T. Ullrich , J. Urakawa , P. VanMechelen , A. Variola , R. Veness , A. Vivoli , P. Vobly , J. Wagner , R. Wallny , S. Wallon , G. Watt , C. Weiss , U. A. Wiedemann , U. Wienands , F. Willeke , B. -W. Xiao , V. Yakimenko , A. F. Zarnecki , Z. Zhang , F. Zimmermann , R. Zlebcik , F. Zomer