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Photoacoustic imaging (PAI) uniquely combines the advantages of optical contrast with deep tissue penetration capability of acoustic waves, enabling imaging at depths of several centimeters. Conventional photoacoustic imaging methods have…

Applied Physics · Physics 2026-02-24 Xingchi Yan , Siyuan Song , Hanxun Jin

In photoacoustic imaging the objective is to determine the optical properties of biological tissue from boundary measurement of the generated acoustic wave. Here, we propose a restriction to piecewise constant media parameters. Precisely we…

Analysis of PDEs · Mathematics 2024-07-09 Yavar Kian , Faouzi Triki

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is an emerging computed biomedical imaging modality that exploits optical contrast and ultrasonic detection principles. Iterative image reconstruction algorithms that…

Medical Physics · Physics 2016-11-17 Kun Wang , Robert W Schoonover , Richard Su , Alexander Oraevsky , Mark A Anastasio

This work studies the inverse problem of photoacoustic tomography (more precisely, the acoustic subproblem) as the identification of a space-dependent source parameter. The model consists of a wave equation involving a time-fractional…

Numerical Analysis · Mathematics 2025-04-29 Phuoc-Truong Huynh , Barbara Kaltenbacher

Absorption spectroscopy is routinely used to characterise chemical and biological samples. For the state-of-the-art in absorption spectroscopy, precision is theoretically limited by shot-noise due to the fundamental Poisson-distribution of…

An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing detection architecture. A wide range of photoacoustic…

Biological Physics · Physics 2021-08-04 Kevan Bell , Lyazzat Mukhangaliyeva , Layla Khalili , Parsin Haji Reza

Optical absorption is a primary, label-defining contrast across biology, pathology, and materials science, yet three-dimensional quantitative absorption imaging has remained largely inaccessible to the brightfield microscopes used in…

Non-invasive imaging of deep blood vessels for mapping hemodynamics remains an open quest in biomedical optical imaging. Although pure optical imaging techniques offer rich optical contrast of blood and have been reported to measure blood…

Medical Physics · Physics 2022-09-20 Yang Zhang , Joshua Olick-Gibson , Anjul Khadria , Lihong V. Wang

Photo-acoustic spectroscopy (PAS) is one of the most sensitive non-destructive analysis techniques for gases, fluids and solids. It can operate background-free at any wavelength and is applicable to microscopic and even non-transparent…

Laser enhanced field evaporation of surface atoms in Laser-assisted Atom Probe Tomography (La-APT) can simultaneously excite phtotoluminescence in semiconductor or insulating specimens. An atom probe equipped with appropriate focalization…

Photoacoustic microscopy (PAM) is a novel implementation of photoacoustic imaging (PAI) for visualizing the 3D bio-structure, which is realized by raster scanning of the tissue. However, as three involved critical imaging parameters,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhengyuan Zhang , Haoran Jin , Zesheng Zheng , Wenwen Zhang , Wenhao Lu , Feng Qin , Arunima Sharma , Manojit Pramanik , Yuanjin Zheng

This paper aims to mathematically advance the field of quantitative thermo-acoustic imaging. Given several electromagnetic data sets, we establish for the first time an analytical formula for reconstructing the absorption coefficient from…

Analysis of PDEs · Mathematics 2014-03-25 Habib Ammari , Josselin Garnier , Wenjia Jing , Loc Nguyen

Speeding up the data acquisition is one of the central aims to advance tomographic imaging. On the one hand, this reduces motion artifacts due to undesired movements, and on the other hand this decreases the examination time for the…

Numerical Analysis · Mathematics 2015-01-20 Michael Sandbichler , Felix Krahmer , Thomas Berer , Peter Burgholzer , Markus Haltmeier

Photoacoustic imaging is an emerging technology based on the photoacoustic effect that has developed rapidly in recent years. It combines the high contrast of optical imaging and the high penetration and high resolution of acoustic imaging.…

Idier et al. [IEEE Trans. Comput. Imaging 4(1), 2018] propose a method which achieves superresolution in the microscopy setting by leveraging random speckle illumination and knowledge about statistical second order moments for the…

Signal Processing · Electrical Eng. & Systems 2022-02-02 Osman Asif Malik , Venkatalakshmi Vyjayanthi Narumanchi , Stephen Becker , Todd W. Murray

We treat the stability issue for the three dimensional inverse imaging modality called Quantitative Photoacoustic Tomography. We provide universal choices of the illuminations which enable to recover, in a H\"older stable fashion, the…

Analysis of PDEs · Mathematics 2015-05-15 Giovanni Alessandrini , Michele Di Cristo , Elisa Francini , Sergio Vessella

Ultrasound attenuation is caused by absorption and scattering in tissue and is thus a function of tissue composition, hence its imaging offers great potential for screening and differential diagnosis. In this paper we propose a novel method…

Signal Processing · Electrical Eng. & Systems 2019-10-15 Richard Rau , Ozan Unal , Dieter Schweizer , Valery Vishnevskiy , Orcun Goksel

Atomic-resolution imaging with scanning transmission electron microscopy is a powerful tool for characterizing the nanoscale structure of materials, in particular features such as defects, local strains, and symmetry-breaking distortions.…

Photoacoustic (PA) imaging is a biomedical imaging modality capable of acquiring high-contrast images of optical absorption at depths much greater than traditional optical imaging techniques. However, practical instrumentation and geometry…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Mengjie Guo , Hengrong Lan , Changchun Yang , Fei Gao

Ultrasound Tomography has seen a revival of interest in the past decade, especially for breast imaging, due to improvements in both ultrasound and computing hardware. In particular, three-dimensional ultrasound tomography, a fully…

Computational Physics · Physics 2020-05-27 Ashkan Javaherian , Felix Lucka , Ben Cox