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In this paper, we present a new technique to dynamically determine the values of program parameters in order to optimize the performance of a multithreaded program P. To be precise, we describe a novel technique to statically build another…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-04 Alexander Brandt , Davood Mohajerani , Marc Moreno Maza , Jeeva Paudel , Lin-Xiao Wang

PLUMED is an open-source software package that is widely used for analyzing and enhancing molecular dynamics simulations that works in conjunction with most available molecular dynamics softwares. While the computational cost of PLUMED…

Computational Physics · Physics 2025-11-05 Daniele Rapetti , Massimiliano Bonomi , Carlo Camilloni , Giovanni Bussi , Gareth A. Tribello

Scanning probe microscopy (SPM) is a valuable technique by which one can investigate the physical characteristics of the surfaces of materials. However, its widespread use is hampered by the time-consuming nature of running an experiment…

Instrumentation and Detectors · Physics 2025-09-03 Nicholas J. Sullivan , Julio J. Valdés , Kirk H. Bevan , Peter Grutter

Particle-in-cell methods with stochastic collision models are commonly used to simulate collisional plasma dynamics, with applications ranging from hypersonic flight to semiconductor manufacturing. Code verification of such methods is…

Computational Physics · Physics 2026-05-26 Brian A. Freno , William J. McDoniel , Christopher H. Moore , Neil R. Matula

Background: Software Process Simulation (SPS) has become an effective tool for software process management and improvement. However, its adoption in industry is less than what the research community expected due to the burden of measurement…

Software Engineering · Computer Science 2023-01-18 Bohan Liu , He Zhang , Liming Dong , Zhiqi Wang , Shanshan Li

Parametric model checking (PMC) computes algebraic formulae that express key non-functional properties of a system (reliability, performance, etc.) as rational functions of the system and environment parameters. In software engineering, PMC…

Software Engineering · Computer Science 2021-02-03 Xinwei Fang , Radu Calinescu , Simos Gerasimou , Faisal Alhwikem

Molecular simulations are an important tool for research in physics, chemistry, and biology. The capabilities of simulations can be greatly expanded by providing access to advanced sampling methods and techniques that permit calculation of…

Robust optimization provides a principled and unified framework to model many problems in modern operations research and computer science applications, such as risk measures minimization and adversarially robust machine learning. To use a…

Optimization and Control · Mathematics 2024-10-04 Hao Hao , Peter Zhang

Linear programming (LP) is an extremely useful tool and has been successfully applied to solve various problems in a wide range of areas, including operations research, engineering, economics, or even more abstract mathematical areas such…

Data Structures and Algorithms · Computer Science 2020-03-19 Agniva Chowdhury , Palma London , Haim Avron , Petros Drineas

Automatic software system optimization can improve software speed, reduce operating costs, and save energy. Traditional approaches to optimization rely on manual tuning and compiler heuristics, limiting their ability to generalize across…

Parallel programs in high performance computing (HPC) continue to grow in complexity and scale in the exascale era. The diversity in hardware and parallel programming models make developing, optimizing, and maintaining parallel software…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-15 Daniel Nichols , Aniruddha Marathe , Harshitha Menon , Todd Gamblin , Abhinav Bhatele

Embedded controllers for cyber-physical systems are often parameterized by look-up maps representing discretizations of continuous functions on metric spaces. For example, a non-linear control action may be represented as a table of…

Systems and Control · Computer Science 2017-10-10 Jyotirmoy V. Deshmukh , Xiaoqing Jin , Rupak Majumdar , Vinayak S. Prabhu

Software systems usually provide numerous configuration options that can affect performance metrics such as execution time, memory usage, binary size, or bitrate. On the one hand, making informed decisions is challenging and requires domain…

Many recently introduced enhanced sampling techniques are based on biasing coarse descriptors (collective variables) of a molecular system on the fly. Sometimes the calculation of such collective variables is expensive and becomes a…

Computational Physics · Physics 2015-09-01 Marco Jacopo Ferrarotti , Sandro Bottaro , Andrea Pérez-Villa , Giovanni Bussi

The rapid development of pretrained Machine Learning Interatomic Potentials (MLIPs) that cover a wide range of molecular species has made it challenging to select the best model for a given application. We benchmark 15 pretrained MLIPs,…

Chemical Physics · Physics 2026-04-22 Peter Eastman , Evan Pretti , Thomas E. Markland

Model Predictive Control (MPC) is a computationally demanding control technique that allows dealing with multiple-input and multiple-output systems, while handling constraints in a systematic way. The necessity of solving an optimization…

Systems and Control · Computer Science 2021-12-16 Bulat Khusainov , Eric C. Kerrigan , George A. Constantinides

We present the basic idea, implementation, measured performance and performance model of FDPS (Framework for developing particle simulators). FDPS is an application-development framework which helps the researchers to develop particle-based…

Instrumentation and Methods for Astrophysics · Physics 2016-06-15 Masaki Iwasawa , Ataru Tanikawa , Natsuki Hosono , Keigo Nitadori , Takayuki Muranushi , Junichiro Makino

Generality is one of the main advantages of heuristic algorithms, as such, multiple parameters are exposed to the user with the objective of allowing them to shape the algorithms to their specific needs. Parameter selection, therefore,…

Neural and Evolutionary Computing · Computer Science 2017-05-22 Carlos Garcia Cordero

Efficient sampling in biomolecular simulations is critical for accurately capturing the complex dynamical behaviors of biological systems. Adaptive sampling techniques aim to improve efficiency by focusing computational resources on the…

Biomolecules · Quantitative Biology 2024-10-22 Hassan Nadeem , Diwakar Shukla

Optimization models with decision variables in multiple time scales are widely used across various fields such as integrated planning and scheduling. To address scalability challenges in these models, we present the Parametric Autotuning…

Optimization and Control · Mathematics 2024-07-24 Asha Ramanujam , Can Li