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Single-molecule experiments have found near-perfect thermodynamic efficiency in the rotary motor F1-ATP synthase. To help elucidate the principles underlying nonequilibrium energetic efficiency in such stochastic machines, we investigate…

Statistical Mechanics · Physics 2019-09-05 Joseph N. E. Lucero , Aliakbar Mehdizadeh , David A. Sivak

A fundamental result of thermodynamic geometry is that the optimal, minimal-work protocol that drives a nonequilibrium system between two thermodynamic states in the slow-driving limit is given by a geodesic of the friction tensor, a…

Statistical Mechanics · Physics 2024-10-24 Adrianne Zhong , Michael R. DeWeese

Driven barrier crossings are pervasive in optical-trapping experiments and steered molecular-dynamics simulations. Despite the high fidelity of control, the freedom in the choice of driving protocol is rarely exploited to improve…

Statistical Mechanics · Physics 2022-07-06 Steven Blaber , David A. Sivak

We review recent progress in optimal control in stochastic thermodynamics. Theoretical advances provide in-depth insight into minimum-dissipation control with either full or limited (parametric) control, and spanning the limits from slow to…

Statistical Mechanics · Physics 2023-04-13 Steven Blaber , David A. Sivak

Controlling thermodynamic cycles to minimize the dissipated heat is a longstanding goal in thermodynamics, and more recently, a central challenge in stochastic thermodynamics for nanoscale systems. Here, we introduce a theoretical and…

Statistical Mechanics · Physics 2023-03-15 Shriram Chennakesavalu , Grant M. Rotskoff

A central goal of thermodynamics is to identify optimal processes during which the least amount of energy is dissipated into the environment. Generally, even for simple systems, such as the parametric harmonic oscillator, optimal control…

Statistical Mechanics · Physics 2018-10-11 Marcus V. S. Bonança , Sebastian Deffner

A fundamental problem in modern thermodynamics is how a molecular-scale machine performs useful work, while operating away from thermal equilibrium without excessive dissipation. To this end, we derive a friction tensor that induces a…

Statistical Mechanics · Physics 2012-05-09 David A. Sivak , Gavin E. Crooks

We characterize finite-time thermodynamic processes of multidimensional quadratic overdamped systems. Analytic expressions are provided for heat, work, and dissipation for any evolution of the system covariance matrix. The Bures-Wasserstein…

Statistical Mechanics · Physics 2022-11-28 Paolo Abiuso , Viktor Holubec , Janet Anders , Zhuolin Ye , Federico Cerisola , Martí Perarnau-Llobet

We demonstrate that the thermodynamic friction metric governing dissipation in slowly driven continuous-time Markov chains is equivalent to the commute-time embedding and the resistance distance. This equivalence yields complementary…

Statistical Mechanics · Physics 2026-03-30 Jordan R Sawchuk , David A Sivak

Optimal control of stochastic systems plays a central role in nonequilibrium physics, with applications in the study of biological molecular motors and the design of single-molecule experiments. While exact analytic solutions to…

Statistical Mechanics · Physics 2026-01-07 Jordan R. Sawchuk , David A. Sivak

We study thermodynamic processes in contact with a heat bath that may have an arbitrary time-varying periodic temperature profile. Within the framework of stochastic thermodynamics, and for models of thermo-dynamic engines in the idealized…

Optimization and Control · Mathematics 2022-04-06 Olga Movilla Miangolarra , Rui Fu , Amirhossein Taghvaei , Yongxin Chen , Tryphon T. Georgiou

Optimal processes in stochastic thermodynamics are a frontier for understanding the control and design of non-equilibrium systems, with broad practical applications in biology, chemistry, and nanoscale/mesoscale systems. Optimal mass…

Statistical Mechanics · Physics 2026-01-15 Atul Tanaji Mohite , Heiko Rieger

We show that energy dissipation in slowly-driven, Markovian quantum systems at low temperature is linked to the geometry of the driving protocol through the quantum (or Fubini-Study) metric. Utilizing these findings, we establish lower…

Quantum Physics · Physics 2025-03-21 Iliya Esin , Étienne Lantagne-Hurtubise , Frederik Nathan , Gil Refael

Transferring a physical system from an initial to a final state while minimizing energetic losses is an interdisciplinary control problem that bridges stochastic thermodynamics and optimal transport theory. Recent research typically…

Statistical Mechanics · Physics 2026-02-23 Jann van der Meer , Andreas Dechant

Active matter constantly dissipates energy to power the self-propulsion of its microscopic constituents. This opens the door to designing innovative cyclic engines without any equilibrium equivalent. We offer a consistent thermodynamic…

Soft Condensed Matter · Physics 2020-07-08 Timothy Ekeh , Michael E. Cates , Étienne Fodor

Nonequilibrium physics encompasses a broad range of natural and synthetic small-scale systems. Optimizing transitions of such systems will be crucial for the development of nanoscale technologies and may reveal the physical principles…

Statistical Mechanics · Physics 2015-09-23 Patrick R. Zulkowski , Michael R. DeWeese

Advances in experimental techniques enable the precise manipulation of a large variety of active systems, which constantly dissipate energy to sustain nonequilibrium phenomena without any equilibrium equivalent. To design novel materials…

Statistical Mechanics · Physics 2025-06-03 Artur Soriani , Elsen Tjhung , Étienne Fodor , Tomer Markovich

Recent studies have explored finite-time dissipation-minimizing protocols for stochastic thermodynamic systems driven arbitrarily far from equilibrium, when granted full external control to drive the system. However, in both simulation and…

Statistical Mechanics · Physics 2022-10-27 Adrianne Zhong , Michael R. DeWeese

Controlling the evolution of nonequilibrium systems to minimize dissipated heat or work is a key goal for designing nanodevices, both in nanotechnology and biology. Progress in computing optimal protocols has thus far been limited to either…

Computational Physics · Physics 2022-01-04 Megan C. Engel , Jamie A. Smith , Michael P. Brenner

A common approach to quantify excess dissipation in slowly driven thermodynamic processes is through the use of a Riemannian metric on the space of control parameters, where optimal driving protocols follow geodesics. Near phase…

Statistical Mechanics · Physics 2025-12-02 Omer M. Basri , Oren Raz
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