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The wide implementation of electronic health record (EHR) systems facilitates the collection of large-scale health data from real clinical settings. Despite the significant increase in adoption of EHR systems, this data remains largely…

Quantitative Methods · Quantitative Biology 2018-10-26 Jinghe Zhang , Kamran Kowsari , James H. Harrison , Jennifer M. Lobo , Laura E. Barnes

We develop an unsupervised probabilistic model for heterogeneous Electronic Health Record (EHR) data. Utilizing a mixture model formulation, our approach directly models sequences of arbitrary length, such as medications and laboratory…

Machine Learning · Computer Science 2022-09-02 Alan D. Kaplan , John D. Greene , Vincent X. Liu , Priyadip Ray

Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…

Machine Learning · Computer Science 2022-11-15 Yuxi Liu , Shaowen Qin , Antonio Jimeno Yepes , Wei Shao , Zhenhao Zhang , Flora D. Salim

AIMS. This study compared the performance of deep learning extensions of survival analysis models with traditional Cox proportional hazards (CPH) models for deriving cardiovascular disease (CVD) risk prediction equations in national health…

Machine Learning · Computer Science 2020-12-01 Sebastiano Barbieri , Suneela Mehta , Billy Wu , Chrianna Bharat , Katrina Poppe , Louisa Jorm , Rod Jackson

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

Machine Learning · Computer Science 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Predicting the incidence of complex chronic conditions such as heart failure is challenging. Deep learning models applied to rich electronic health records may improve prediction but remain unexplainable hampering their wider use in medical…

Dynamic predictive modelling using electronic health record (EHR) data has gained significant attention in recent years. The reliability and trustworthiness of such models depend heavily on the quality of the underlying data, which is, in…

Databases of electronic health records (EHRs) are increasingly used to inform clinical decisions. Machine learning methods can find patterns in EHRs that are predictive of future adverse outcomes. However, statistical models may be built…

Machine Learning · Statistics 2018-12-04 Andrew C. Miller , Ziad Obermeyer , Sendhil Mullainathan

Deep learning-based predictive models, leveraging Electronic Health Records (EHR), are receiving increasing attention in healthcare. An effective representation of a patient's EHR should hierarchically encompass both the temporal…

Machine Learning · Computer Science 2024-05-08 Jiayuan Chen , Changchang Yin , Yuanlong Wang , Ping Zhang

Cardiovascular diseases, including Heart Failure (HF), remain a leading global cause of mortality, often evading early detection. In this context, accessible and effective risk assessment is indispensable. Traditional approaches rely on…

Signal Processing · Electrical Eng. & Systems 2024-03-26 Sergio González , Abel Ko-Chun Yi , Wan-Ting Hsieh , Wei-Chao Chen , Chun-Li Wang , Victor Chien-Chia Wu , Shang-Hung Chang

The continuously increasing cost of the US healthcare system has received significant attention. Central to the ideas aimed at curbing this trend is the use of technology, in the form of the mandate to implement electronic health records…

Information Retrieval · Computer Science 2017-03-24 Pranjul Yadav , Michael Steinbach , Vipin Kumar , Gyorgy Simon

Learning from longitudinal electronic health records is limited if it does not capture the temporal trajectories of the patient's state in a clinical setting. Graph models allow us to capture the hidden dependencies of the multivariate…

Machine Learning · Computer Science 2025-03-31 Munib Mesinovic , Soheila Molaei , Peter Watkinson , Tingting Zhu

Electronic Health Record (EHR) data has been of tremendous utility in Artificial Intelligence (AI) for healthcare such as predicting future clinical events. These tasks, however, often come with many challenges when using classical machine…

Machine Learning · Computer Science 2021-04-08 Tingyi Wanyan , Jing Zhang , Ying Ding , Ariful Azad , Zhangyang Wang , Benjamin S Glicksberg

Survival analysis has been developed and applied in the number of areas including manufacturing, finance, economics and healthcare. In healthcare domain, usually clinical data are high-dimensional, sparse and complex and sometimes there…

Machine Learning · Computer Science 2018-08-13 Milad Zafar Nezhad , Najibesadat Sadati , Kai Yang , Dongxiao Zhu

Electronic medical records (EMR) contain longitudinal information about patients that can be used to analyze outcomes. Typically, studies on EMR data have worked with established variables that have already been acknowledged to be…

Machine Learning · Computer Science 2017-11-30 Prithwish Chakraborty , Vishrawas Gopalakrishnan , Sharon M. H. Alford , Faisal Farooq

In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

Machine Learning · Computer Science 2026-04-09 Manar D. Samad , Yina Hou , Shrabani Ghosh

Survival analysis (SA) models have been widely studied in mining electronic health records (EHRs), particularly in forecasting the risk of critical conditions for prioritizing high-risk patients. However, their vulnerability to adversarial…

Machine Learning · Computer Science 2024-12-30 Mohsen Nayebi Kerdabadi , Arya Hadizadeh Moghaddam , Bin Liu , Mei Liu , Zijun Yao

Conventional machine learning models, particularly tree-based approaches, have demonstrated promising performance across various clinical prediction tasks using electronic health record (EHR) data. Despite their strengths, these models…

Computation and Language · Computer Science 2025-05-26 Sara Ketabi , Dhanesh Ramachandram

Survival models can help medical practitioners to evaluate the prognostic importance of clinical variables to patient outcomes such as mortality or hospital readmission and subsequently design personalized treatment regimes. Electronic…

Machine Learning · Computer Science 2024-04-18 Yixuan Li , Archer Y. Yang , Ariane Marelli , Yue Li