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Much of the natural variation for a complex trait can be explained by variation in DNA sequence levels. As part of sequence variation, gene-gene interaction has been ubiquitously observed in nature, where its role in shaping the development…

Applications · Statistics 2012-10-01 Shaoyu Li , Yuehua Cui

This work presents a new approach for classification of genomic sequences from measurements of complex networks and information theory. For this, it is considered the nucleotides, dinucleotides and trinucleotides of a genomic sequence. For…

Computational Engineering, Finance, and Science · Computer Science 2014-12-19 Bruno Mendes Moro Conque , André Yoshiaki Kashiwabara , Fabrício Martins Lopes

This paper presents a novel DNA sequences alignment method based on inverted index. Now most large scale information retrieval system are all use inverted index as the basic data structure. But its application in DNA sequence alignment is…

Genomics · Quantitative Biology 2013-07-02 Wang Liang , Zhao KaiYong

Sequencing by synthesis is the underlying technology for many next-generation DNA sequencing platforms. We developed a new model, the fixed flow cycle model, to derive the distributions of sequence length for a given number of flow cycles…

Genomics · Quantitative Biology 2024-05-28 Yong Kong

Using basic properties of p-adic numbers, we consider a simple new approach to describe main aspects of DNA sequence and genetic code. Central role in our investigation plays an ultrametric p-adic information space which basic elements are…

Genomics · Quantitative Biology 2010-12-01 Branko Dragovich , Alexandra Dragovich

In this paper, we review the literature on statistical long-range correlation in DNA sequences. We examine the current evidence for these correlations, and conclude that a mixture of many length scales (including some relatively long ones)…

chao-dyn · Physics 2009-10-22 Wentian Li , Thomas G. Marr , Kunihiko Kaneko

After the recent advancement of sequencing strategies, mirror repeats have been found to be present in the gene sequence of many organisms and species. This presence of mirror repeats in most of the sequences indicates towards some…

Genomics · Quantitative Biology 2013-12-16 Bhardwaj Vikash , Gupta Swapni , Meena Sitaram , Sharma Kulbhushan

We introduce the software tool NTRFinder to find the complex repetitive structure in DNA we call a nested tandem repeat (NTR). An NTR is a recurrence of two or more distinct tandem motifs interspersed with each other. We propose that nested…

Quantitative Methods · Quantitative Biology 2011-05-04 A. A. Matroud , M. D. Hendy , C. P. Tuffley

An essential quantity to ensure evolvability of populations is the navigability of the genotype space. Navigability relies on the existence of sufficiently large genotype networks, that is ensembles of sequences with the same phenotype that…

Populations and Evolution · Quantitative Biology 2017-04-20 Susanna Manrubia , Jose A. Cuesta

High-throughput sequencing of RNA transcripts (RNA-seq) has become the method of choice for detection of differential expression (DE). Concurrent with the growing popularity of this technology there has been a significant research effort…

We introduce a powerful recurrent neural network based method for novelty detection to the application of detecting radio anomalies. This approach holds promise in significantly increasing the ability of naive anomaly detection to detect…

Machine Learning · Computer Science 2016-11-02 Timothy J O'Shea , T. Charles Clancy , Robert W. McGwier

We present a framework for efficient inference in structured image models that explicitly reason about objects. We achieve this by performing probabilistic inference using a recurrent neural network that attends to scene elements and…

Computer Vision and Pattern Recognition · Computer Science 2016-08-15 S. M. Ali Eslami , Nicolas Heess , Theophane Weber , Yuval Tassa , David Szepesvari , Koray Kavukcuoglu , Geoffrey E. Hinton

In this paper we consider the problem of detecting statistically significant sequential patterns in multi-neuronal spike trains. These patterns are characterized by ordered sequences of spikes from different neurons with specific delays…

Neurons and Cognition · Quantitative Biology 2008-08-28 P. S. Sastry , K. P. Unnikrishnan

This paper rigorously solves the challenging problem of recognizing periodic patterns under rigid motion in Euclidean geometry. The 3-dimensional case is practically important for justifying the novelty of solid crystalline materials…

Metric Geometry · Mathematics 2025-10-30 Olga Anosova , Daniel Widdowson , Vitaliy Kurlin

Data mining is the task of discovering interesting patterns from large amounts of data. There are many data mining tasks, such as classification, clustering, association rule mining, and sequential pattern mining. Sequential pattern mining…

Databases · Computer Science 2010-02-08 Mahdi Esmaeili , Fazekas Gabor

Several statistical approaches based on reproducing kernels have been proposed to detect abrupt changes arising in the full distribution of the observations and not only in the mean or variance. Some of these approaches enjoy good…

Statistics Theory · Mathematics 2017-10-13 Alain Celisse , Guillemette Marot , Morgane Pierre-Jean , Guillem Rigaill

Many organisations manage service quality and monitor a large set devices and servers where each entity is associated with telemetry or physical sensor data series. Recently, various methods have been proposed to detect behavioural…

Social and Information Networks · Computer Science 2023-05-10 Len Feremans , Boris Cule , Bart Goethals

The last decades have not only been characterized by an explosive growth of data, but also an increasing appreciation of data as a valuable resource. Their value comes with the ability to extract meaningful patterns that are of economic,…

Machine Learning · Statistics 2020-02-27 Jonas I. Liechti , Sebastian Bonhoeffer

Sequencing a genome to determine an individual's DNA produces an enormous number of short nucleotide subsequences known as reads, which must be reassembled to reconstruct the full genome. We present a method for analyzing this type of data…

Machine Learning · Computer Science 2025-05-23 Filip Thor , Carl Nettelblad

Gene sequences in the vicinity of splice sites are found to possess dinucleotide periodicities, especially RR and YY, with the period close to the pitch of nucleosome DNA. This confirms previously reported finding about preferential…

Genomics · Quantitative Biology 2007-05-23 Simon Kogan , Edward N. Trifonov
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