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We present an asymptotic analysis of a stochastic two-compartmental cell division system with regulatory mechanisms inspired by Getto et al. (2013). The hematopoietic system is modeled as a two-compartment system, where the first…

Populations and Evolution · Quantitative Biology 2025-06-30 Ren-Yi Wang , Marek Kimmel , Guodong Pang

In order to investigate the evolutionary process of many deterministic Dynamical systems with unfixed parameter, a set of dynamical models with parameter changing continuously and the accumulation of this change might be large is introduced…

comp-gas · Physics 2008-02-03 H. P. Fang

A computation-oriented representation of uncertain kinetic systems is introduced and analysed in this paper. It is assumed that the monomial coefficients of the ODEs belong to a polytopic set, which defines a set of dynamical systems for an…

Dynamical Systems · Mathematics 2018-05-23 Bernadett Ács , Gergely Szlobodnyik , Gábor Szederkényi

A piecewise-linear model with a single degree of freedom is derived from first principles for a driven vertical cantilever beam with a localized mass and symmetric stops. The resulting piecewise-linear dynamical system is smoothed by a…

Dynamical Systems · Mathematics 2013-08-19 M. Elmegård , B. Krauskopf , H. M. Osinga , J. Starke , J. J. Thomsen

Mechanistic models with differential equations are a key component of scientific applications of machine learning. Inference in such models is usually computationally demanding, because it involves repeatedly solving the differential…

Machine Learning · Statistics 2022-07-06 Jonathan Schmidt , Nicholas Krämer , Philipp Hennig

A significant challenge in many fields of science and engineering is making sense of time-dependent measurement data by recovering governing equations in the form of differential equations. We focus on finding parsimonious ordinary…

Machine Learning · Computer Science 2024-10-04 Doris Voina , Steven Brunton , J. Nathan Kutz

In this short communication we introduce a rather simple autonomous system of 2 nonlinearly-coupled first-order Ordinary Differential Equations (ODEs), whose initial-values problem is explicitly solvable by algebraic operations. Its ODEs…

Dynamical Systems · Mathematics 2023-06-22 Francesco Calogero , Farrin Payandeh

We study statistical inference for small-noise-perturbed multiscale dynamical systems under the assumption that we observe a single time series from the slow process only. We construct estimators for both averaging and homogenization…

Probability · Mathematics 2018-09-13 Siragan Gailus , Konstantinos Spiliopoulos

We develop symbolic methods of asymptotic approximations for solutions of linear ordinary differential equations and use to them stabilize numerical calculations. Our method follows classical analysis for first-order systems and…

Symbolic Computation · Computer Science 2011-10-12 Christopher J. Winfield

The limiting stability of invariant probability measures of time homogeneous transition semigroups for autonomous stochastic systems has been extensively discussed in the literature. In this paper we initially initiate a program to study…

Analysis of PDEs · Mathematics 2022-03-25 Renhai Wang , Tomas Caraballo , Nguyen Huy Tuan

The hazard function represents one of the main quantities of interest in the analysis of survival data. We propose a general approach for parametrically modelling the dynamics of the hazard function using systems of autonomous ordinary…

Methodology · Statistics 2024-07-19 J. A. Christen , F. J. Rubio

In this paper, we delve into the dynamical properties of a class of three-dimensional logistic ecological models. By using the complete discriminant theory of polynomials, we first give a topological classification for each fixed point and…

Dynamical Systems · Mathematics 2025-05-12 Yujiang Chen , Lin Li , Lingling Liu , Zhiheng Yu

Ordinary differential equation (ODE) models are widely used to describe systems in many areas of science. To ensure these models provide accurate and interpretable representations of real-world dynamics, it is often necessary to infer…

Methodology · Statistics 2026-03-24 Selva Salimi , David J. Warne , Christopher Drovandi

Recent biological evidence suggests the presence of a two-phase ageing process in several species. We introduce a system of two age-structured partial differential equations (PDE) representing two phases of ageing of a wild population. The…

Analysis of PDEs · Mathematics 2026-03-24 Luce Breuil

This paper analyzes the stability of a reactiondiffusion equation coupled with a finite-dimensional controller through Dirichlet boundary input and Neumann boundary output. Going against the flow, we intend to propose numerical certificates…

Optimization and Control · Mathematics 2023-03-09 Mathieu Bajodek , Hugo Lhachemi , Giorgio Valmorbida

We investigate the influence of intrinsic noise on stable states of a one-dimensional dynamical system that shows in its deterministic version a saddle-node bifurcation between monostable and bistable behaviour. The system is a modified…

Statistical Mechanics · Physics 2017-05-03 Johannes Falk , Marc Mendler , Barbara Drossel

For a 2-D coupled PDE-ODE bulk-cell model, we investigate symmetry-breaking bifurcations that can emerge when two bulk diffusing species are coupled to two-component nonlinear intracellular reactions that are restricted to occur only within…

Pattern Formation and Solitons · Physics 2023-01-18 Merlin Pelz , Michael J. Ward

The modelling and analysis of biological systems has deep roots in Mathematics, specifically in the field of ordinary differential equations (ODEs). Alternative approaches based on formal calculi, often derived from process algebras or term…

Programming Languages · Computer Science 2010-11-03 Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Elena Grassi , Eva Sciacca , Salvatore Spinella , Angelo Troina

Mechanistic dynamic models of biochemical networks such as Ordinary Differential Equations (ODEs) contain unknown parameters like the reaction rate constants and the initial concentrations of the compounds. The large number of parameters as…

Data Analysis, Statistics and Probability · Physics 2017-08-14 Clemens Kreutz , Andreas Raue , Jens Timmer

There has been a significant focus on modelling emotion ambiguity in recent years, with advancements made in representing emotions as distributions to capture ambiguity. However, there has been comparatively less effort devoted to the…

Artificial Intelligence · Computer Science 2024-08-01 Jingyao Wu , Ting Dang , Vidhyasaharan Sethu , Eliathamby Ambikairajah