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Partitioning of (bio)materials in polymeric mixtures is a key phenomenon both in cellular environments, as well as in industrial applications. In cells, several macromolecules are suspended within different biomolecular phases. On the other…

Soft Condensed Matter · Physics 2025-10-15 Vikki Anand Varma , Alberto Scacchi

Pore forming toxins (PFTs) are virulent proteins released by several species, including many strains of bacteria, to attack and kill host cells. In this article, we focus on the utility of molecular dynamics (MD) simulations and the…

Soft Condensed Matter · Physics 2021-08-17 Rajat Desikan , Amit Behera , Prabal K. Maiti , K. Ganapathy Ayappa

The aim of this paper is to discuss the mathematical modeling of Brownian active particle systems, a recently popular paradigmatic system for self-propelled particles. We present four microscopic models with different types of repulsive…

Statistical Mechanics · Physics 2022-05-31 M. Bruna , M. Burger , A. Esposito , S. M. Schulz

We discuss different mechanisms for curvature-induced domain formation in multicomponent lipid membranes and present a theoretical model that allows us to study the interplay between the domains. The model represents the membrane by two…

Biological Physics · Physics 2015-11-12 Leonie Brodbek , Friederike Schmid

The computational study of the interaction between charged, ligand-protected metal nanoparticles and model lipid membranes has been recently addressed both at atomistic and coarse grained level. Here we compare the performance of three…

Biological Physics · Physics 2017-03-02 Sebastian Salassi , Federica Simonelli , Davide Bochicchio , Riccardo Ferrando , Giulia Rossi

We establish a biophysical model for the dynamics of lipid vesicles exposed to surfactants. The solubilization of the lipid membrane due to the insertion of surfactant molecules induces a reduction of membrane surface area at almost…

Biological Physics · Physics 2019-04-24 Morgan Chabanon , Padmini Rangamani

We study theoretically the evaporation-driven phase separation of a binary fluid mixture in a thin film deposited on a moving substrate, as occurs in meniscus-guided deposition for solution-processed materials. Our focus is on rapid…

Soft Condensed Matter · Physics 2024-07-01 René de Bruijn , Anton A. Darhuber , Jasper J. Michels , Paul van der Schoot

We propose a continuum theory of the liquid-liquid phase separation in an elastic network where phase-separated microscopic droplets rich in one fluid component can form as an interplay of fluids mixing, droplet nucleation, network…

Soft Condensed Matter · Physics 2021-01-04 Xuefeng Wei , Jiajia Zhou , Yanting Wang , Fanlong Meng

Two temperature induced phase separation(2-TIPS) is a phenomenon observed in mixtures of active and passive particles modeled by scalar activity where the temperature of the particle is proportional to its activity. The binary mixture of…

Soft Condensed Matter · Physics 2025-03-17 Nayana Venkatareddy , Partha Sarathi Mondal , Jaydeep Mandal , Shradha Mishra , Prabal K. Maiti

In this manuscript, we undertake an examination of a classical plasma deployed on two finite co-planar surfaces: a circular region $\Omega_{in}$ into an annular region $\Omega_{out}$ with a gap in between. It is studied both from the point…

Statistical Mechanics · Physics 2024-07-02 Robert Salazar , Cristian Cobos , Diego Jaramillo , Camilo Bayona

Viscoelastic phase separation of colloidal suspensions can be interrupted to form gels either by glass transition or by crystallization. With a new confocal microscopy protocol, we follow the entire kinetics of phase separation, from…

Soft Condensed Matter · Physics 2018-02-05 Hideyo Tsurusawa , John Russo , Mathieu Leocmach , Hajime Tanaka

The dynamics of phase separation in multi-component bilayer fluid vesicles is investigated by means of large-scale dissipative particle dynamics. The model explicitly accounts for solvent particles, thereby allowing for the very first…

Soft Condensed Matter · Physics 2009-11-10 Mohamed Laradji , P. B. Sunil Kumar

In this work, we apply phase field simulations to examine the coarsening behavior of morphologically complex two-phase microstructures in which the phases have highly dissimilar mobilities, a condition approaching that found in experimental…

Materials Science · Physics 2022-06-10 W. Beck Andrews , Peter W. Voorhees , Katsuyo Thornton

In this paper, we report a Brownian dynamics simulation of the mobility-induced phase separation which occurs in a two-dimensional binary mixture of active soft Brownian particles, whose interactions are modeled by non-additive…

Soft Condensed Matter · Physics 2026-01-23 D. Jiménez-Flores , A. Rodríguez-Rivas , J. M. Romero-Enrique

Many-body dissipative particle dynamics (MDPD) offers a significant speed-up in the simulation of various systems, including soft matter, in comparison with molecular dynamics (MD) simulations based on Lennard-Jones nteractions, which is…

Soft Condensed Matter · Physics 2025-06-09 Natalia Kramarz , Luís H. Carnevale , Panagiotis E. Theodorakis

We study the indentation of a free-standing lipid membrane suspended over a nanopore on a hydrophobic substrate by means of molecular dynamics simulations. We find that in the course of indentation, the membrane bends at the point of…

Soft Condensed Matter · Physics 2011-08-26 Chen-Hsi Huang , Pai-Yi Hsiao , Fan-Gang Tseng , Shih-Kang Fan , Chien-Chung Fu , Rong-Long Pan

A new model for the interaction of an electric pulse with a lipid membrane is proposed. Using this model we show that when a DC electric pulse is applied to an insulating lipid membrane separating fluids with different conductivities, the…

Biological Physics · Physics 2015-05-18 Jonathan T. Schwalbe , Petia M. Vlahovska , Michael J. Miksis

We describe a concept that has the potential to change how we think about the underlying mechanisms of cell membrane electroporation (EP). Prior experimental, theoretical and modeling have emphasized a single pore lifetime as adequate for…

Biological Physics · Physics 2017-08-28 Julie V. Stern , Thiruvallur R. Gowrishankar , Kyle C. Smith , James C. Weaver

We present a simple coarse-grained bead-and-spring model for lipid bilayers. The system has been developed to reproduce the main (gel-liquid) transition of biological membranes on intermediate length scales of a couple of nanometres and is…

Soft Condensed Matter · Physics 2007-05-23 Olaf Lenz , Friederike Schmid

It was recently discovered that friction between surfaces bearing phosphatidylcholine (PC) lipid bilayers can be increased by two orders of magnitude or more via an externally-applied electric field, and that this increase is fully…

Soft Condensed Matter · Physics 2024-09-26 Di Jin , Jacob Klein