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We present McGenus, an algorithm to predict RNA secondary structures with pseudoknots. The method is based on a classification of RNA structures according to their topological genus. McGenus can treat sequences of up to 1000 bases and…

Biomolecules · Quantitative Biology 2013-02-18 M. Bon , C. Micheletti , H. Orland

It has recently been reported [Phys. Rev. Lett. 117, 162502 (2016)] that (d, p) cross sections can be very sensitive to the n-p interactions used in the adiabatic treatment of deuteron breakup with nonlocal nucleon-target optical…

Nuclear Theory · Physics 2018-08-15 M. Gómez-Ramos , N. K. Timofeyuk

We develop a reaction model for $\eta$ photoproduction off the deuteron ($\gamma d\to\eta pn$), and study the reaction at a special kinematics, where the photon beam energy is $\sim 0.94$ GeV and the scattered proton is detected at $\sim…

Nuclear Theory · Physics 2017-11-01 S. X. Nakamura , H. Kamano , T. Ishikawa

We present a fast and feature-complete differentiable physics engine, Nimble (nimblephysics.org), that supports Lagrangian dynamics and hard contact constraints for articulated rigid body simulation. Our differentiable physics engine offers…

Robotics · Computer Science 2021-06-24 Keenon Werling , Dalton Omens , Jeongseok Lee , Ioannis Exarchos , C. Karen Liu

Graph convolutional networks (GCNs) based methods have achieved advanced performance on skeleton-based action recognition task. However, the skeleton graph cannot fully represent the motion information contained in skeleton data. In…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Jinfeng Wei , Yunxin Wang , Mengli Guo , Pei Lv , Xiaoshan Yang , Mingliang Xu

The advent of deep learning has introduced efficient approaches for de novo protein sequence design, significantly improving success rates and reducing development costs compared to computational or experimental methods. However, existing…

Artificial Intelligence · Computer Science 2024-07-11 Yutong Hu , Yang Tan , Andi Han , Lirong Zheng , Liang Hong , Bingxin Zhou

Range-separated methods combining a short-range density functional with long-range random phase approximations RPAs with or without exchange response kernel are tested on rare-gas dimers and the S22 benchmark set of weakly interacting…

Chemical Physics · Physics 2014-04-10 Wuming Zhu , Julien Toulouse , Andreas Savin , János G. Angyán

Predicting drug-target binding affinity (DTA) is essential for identifying potential therapeutic candidates in drug discovery. However, most existing models rely heavily on static protein structures, often overlooking the dynamic nature of…

Robotics · Computer Science 2025-05-20 Dan Luo , Jinyu Zhou , Le Xu , Sisi Yuan , Xuan Lin

Generative Adversarial Networks (GANs) have the capability of synthesizing images, which have been successfully applied to medical image synthesis tasks. However, most of existing methods merely consider the global contextual information…

Computer Vision and Pattern Recognition · Computer Science 2019-08-14 Tianyang Zhang , Huazhu Fu , Yitian Zhao , Jun Cheng , Mengjie Guo , Zaiwang Gu , Bing Yang , Yuting Xiao , Shenghua Gao , Jiang Liu

Background: Timely, uncertainty-aware forecasting from irregular electronic health records (EHR) can support critical-care decisions, yet most approaches either impute to a grid or sacrifice interpretability. We introduce StructGP, a…

Machine Learning · Computer Science 2026-05-01 Ivan Lerner , Jean Feydy , Alexandre Kalimouttou , Anita Burgun , Francis Bach

To sample rare events, dissipation-corrected targeted molecular dynamics (dcTMD) applies a constant velocity constraint along a one-dimensional reaction coordinate $s$, which drives an atomistic system from an initial state into a target…

Biological Physics · Physics 2023-09-19 Matthias Post , Steffen Wolf , Gerhard Stock

Surrogate models for the rapid inference of nonlinear boundary value problems in mechanics are helpful in a broad range of engineering applications. However, effective surrogate modeling of applications involving the contact of deformable…

Computational Engineering, Finance, and Science · Computer Science 2025-07-21 Vijay K. Dubey , Collin E. Haese , Osman Gültekin , David Dalton , Manuel K. Rausch , Jan N. Fuhg

39 detailed mechanisms for combustion of hydrogen, carbon monoxide and methanol are investigated using ReactionKinetics, a Mathematica based package. The obtained results in most cases do not depend on the choice of reaction rate…

Chemical Physics · Physics 2013-08-06 J. Tóth , A. L. Nagy , I. Zsély

In recent years, there has been an increasing need for Nuclear Power Plants (NPPs) to improve flexibility in order to match the rapid growth of renewable energies. The Operator Assistance Predictive System (OAPS) developed by Framatome…

Machine Learning · Computer Science 2026-03-26 Perceval Beja-Battais , Alain Grossetête , Nicolas Vayatis

The increasing availability of high-dimensional, longitudinal measures of gene expression can facilitate understanding of biological mechanisms, as required for precision medicine. Biological knowledge suggests that it may be best to…

Applications · Statistics 2025-04-18 Jiachen Cai , Robert J. B. Goudie , Colin Starr , Brian D. M. Tom

Although robotic applications increasingly demand versatile and dynamic object handling, most existing techniques are predominantly focused on grasp-based manipulation, limiting their applicability in non-prehensile tasks. To address this…

Robotics · Computer Science 2025-02-25 Hamidreza Raei , Elena De Momi , Arash Ajoudani

The strongly-contracted variant of second order N -electron valence state perturbation theory (NEVPT2) is an efficient perturbative method to treat dynamic correlation without the problems of intruder states or level shifts, while the…

Chemical Physics · Physics 2016-04-14 Sheng Guo , Mark A. Watson , Weifeng Hu , Qiming Sun , Garnet Kin-Lic Chan

Prediction of complete step-by-step chemical reaction mechanisms (CRMs) remains a major challenge. Whereas the traditional approaches in CRM tasks rely on expert-driven experiments or costly quantum chemical computations, contemporary deep…

Chemical Physics · Physics 2025-12-11 Manajit Das , Ajnabiul Hoque , Mayank Baranwal , Raghavan B. Sunoj

We calculate dilepton spectra in heavy-ion collisions using a coarse-graining approach to the simulation of the created medium with the UrQMD transport model. This enables the use of dilepton-production rates evaluated in equilibrium…

High Energy Physics - Phenomenology · Physics 2016-02-17 H. van Hees , S. Endres , J. Weil , M. Bleicher

Dilepton and photon production in heavy-ion collisions at SPS energies is studied in the relativistic transport model that incorporates self-consistently the change of hadron masses in dense matter. It is found that the dilepton spectra in…

Nuclear Theory · Physics 2007-05-23 G. Q. Li , G. E. Brown , C. Gale , C. M. Ko