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Single-molecule localization microscopy (SMLM) allows reconstructing biology-relevant structures beyond the diffraction limit by detecting and localizing individual fluorophores -- fluorescent molecules stained onto the observed specimen --…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Romain Seailles , Jean-Baptiste Masson , Jean Ponce , Julien Mairal

MINFLUX (Minimal Photon Flux) is a single-molecule imaging technique capable of resolving fluorophores at a precision of <5 nm. Interpretation of the point patterns generated by this technique presents challenges due to variable emitter…

Applications · Statistics 2026-02-24 Jack Peyton , Benjamin Davis , Emily Gribbin , Daniel Rolfe , Hannah Mitchell

Most image restoration problems are ill-conditioned or ill-posed and hence involve significant uncertainty. Quantifying this uncertainty is crucial for reliably interpreting experimental results, particularly when reconstructed images…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Jasper M. Everink , Bernardin Tamo Amougou , Marcelo Pereyra

This paper investigates methods for estimating uncertainty in semantic segmentation predictions derived from satellite imagery. Estimating uncertainty for segmentation presents unique challenges compared to standard image classification,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Melanie Rey , Andriy Mnih , Maxim Neumann , Matt Overlan , Drew Purves

The optics of any camera degrades the sharpness of photographs, which is a key visual quality criterion. This degradation is characterized by the point-spread function (PSF), which depends on the wavelengths of light and is variable across…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Thomas Eboli , Jean-Michel Morel , Gabriele Facciolo

MRI reconstruction techniques based on deep learning have led to unprecedented reconstruction quality especially in highly accelerated settings. However, deep learning techniques are also known to fail unexpectedly and hallucinate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Paul Fischer , Thomas Küstner , Christian F. Baumgartner

We consider the problem of uncertainty quantification in change point regressions, where the signal can be piecewise polynomial of arbitrary but fixed degree. That is we seek disjoint intervals which, uniformly at a given confidence level,…

Methodology · Statistics 2024-12-12 Shakeel Gavioli-Akilagun , Piotr Fryzlewicz

This paper studies the problem of exact localization of sparse (point or extended) objects with noisy data. The crux of the proposed approach consists of random illumination. Several recovery methods are analyzed: the Lasso, BPDN and the…

Information Theory · Computer Science 2015-05-19 Albert Fannjiang

Tracking cells in 3D at high speed continues to attract extensive attention for many biomedical applications, such as monitoring immune cell migration and observing tumor metastasis in flowing blood vessels. Here, we propose a deep…

Optics · Physics 2018-05-16 Kan Liu , Hui Qiao , Jiamin Wu , Haoqian Wang , Lu Fang , Qionghai Dai

We study mathematical and computational models for computing the deformation of fiber-reinforced cross-plied laminates due to external forces. This requires an understanding of both micro-structural effects and different sources of…

Numerical Analysis · Mathematics 2016-04-20 Ivo Babuska , Mohammad Motamed

Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

Medical Physics · Physics 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

The uncertainty quantification of sensor measurements coupled with deep learning networks is crucial for many robotics systems, especially for safety-critical applications such as self-driving cars. This paper develops an uncertainty…

Robotics · Computer Science 2025-06-23 Qiyuan Wu , Mark Campbell

Estimating and disentangling epistemic uncertainty, uncertainty that is reducible with more training data, and aleatoric uncertainty, uncertainty that is inherent to the task at hand, is critically important when applying machine learning…

Machine Learning · Computer Science 2024-11-08 Matthew A. Chan , Maria J. Molina , Christopher A. Metzler

All observations by the aperture photometer (PHT-P) and the far-infrared (FIR) camera section (PHT-C) of ISOPHOT included reference measurements against stable internal fine calibration sources (FCS) to correct for temporal drifts in…

Perspective-n-Point-and-Line (P$n$PL) algorithms aim at fast, accurate, and robust camera localization with respect to a 3D model from 2D-3D feature correspondences, being a major part of modern robotic and AR/VR systems. Current…

Computer Vision and Pattern Recognition · Computer Science 2021-07-09 Alexander Vakhitov , Luis Ferraz Colomina , Antonio Agudo , Francesc Moreno-Noguer

Beyond novel view synthesis, Neural Radiance Fields are useful for applications that interact with the real world. In this paper, we use them as an implicit map of a given scene and propose a camera relocalization algorithm tailored for…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Arthur Moreau , Nathan Piasco , Moussab Bennehar , Dzmitry Tsishkou , Bogdan Stanciulescu , Arnaud de La Fortelle

Digital fringe projection (DFP) enables micrometer-level 3D reconstruction, yet extending it to large-scale mapping remains challenging because six-degree-of-freedom pose estimation often cannot match the reconstruction's precision.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Sehoon Tak , Keunhee Cho , Sangpil Kim , Jae-Sang Hyun

Photoplethysmography (PPG) signals encode information about relative changes in blood volume that can be used to assess various aspects of cardiac health non-invasively, e.g.\ to detect atrial fibrillation (AF) or predict blood pressure…

Machine Learning · Computer Science 2025-05-19 Ciaran Bench , Vivek Desai , Mohammad Moulaeifard , Nils Strodthoff , Philip Aston , Andrew Thompson

Single Particle Tracking (SPT) is a powerful class of tools for analyzing the dynamics of individual biological macromolecules moving inside living cells. The acquired data is typically in the form of a sequence of camera images that are…

Biomolecules · Quantitative Biology 2020-01-23 Ye Lin , Sean B. Andersson

In fluorescence microscopy, Single Molecule Localization Microscopy (SMLM) techniques aim at localizing with high precision high density fluorescent molecules by stochastically activating and imaging small subsets of blinking emitters.…