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This work addresses image restoration tasks through the lens of inverse problems using unpaired datasets. In contrast to traditional approaches -- which typically assume full knowledge of the forward model or access to paired degraded and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Giacomo Meanti , Thomas Ryckeboer , Michael Arbel , Julien Mairal

Although many advances have been made in light-field and camera-array image processing, there is still a lack of thorough analysis of the localisation accuracy of different multi-camera systems. By considering the problem from a…

Computer Vision and Pattern Recognition · Computer Science 2016-02-25 Alireza Ghasemi , Adam Scholefield , Martin Vetterli

The moment method is an image analysis technique for sub-pixel estimation of particle positions. The total error in the calculated particle position includes effects of pixel locking and random noise in each pixel. Pixel locking, also known…

Plasma Physics · Physics 2011-05-23 Yan Feng , J. Goree , Bin Liu

In Visual Place Recognition (VPR) the pose of a query image is estimated by comparing the image to a map of reference images with known reference poses. As is typical for image retrieval problems, a feature extractor maps the query and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Mubariz Zaffar , Liangliang Nan , Julian F. P. Kooij

In this work, we study the conditions under which fluorescent beads can be used to emulate single fluorescent molecules in the calibration of optical microscopes. Although beads are widely used due to their brightness and easy manipulation,…

In this work we present a new algorithm for data deconvolution that allows the retrieval of the target function with super-resolution with a simple approach that after a precis e measurement of the instrument response function (IRF), the…

Computer Vision and Pattern Recognition · Computer Science 2018-12-07 Sandra Martínez , Oscar E. Martínez

Image-based precision medicine aims to personalize treatment decisions based on an individual's unique imaging features so as to improve their clinical outcome. Machine learning frameworks that integrate uncertainty estimation as part of…

Machine Learning · Computer Science 2023-08-11 Joshua Durso-Finley , Jean-Pierre Falet , Raghav Mehta , Douglas L. Arnold , Nick Pawlowski , Tal Arbel

Deep learning has become an extremely effective tool for image classification and image restoration problems. Here, we apply deep learning to microscopy, and demonstrate how neural networks can exploit the chromatic dependence of the…

Optics · Physics 2018-07-05 Eran Hershko* , Lucien E. Weiss* , Tomer Michaeli , Yoav Shechtman

Robustly and accurately localizing objects in real-world environments can be challenging due to noisy data, hardware limitations, and the inherent randomness of physical systems. To account for these factors, existing works estimate the…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Moussa Kassem Sbeyti , Michelle Karg , Christian Wirth , Azarm Nowzad , Sahin Albayrak

Uncertainty quantification for Particle Image Velocimetry (PIV) is critical for comparing flow fields with Computational Fluid Dynamics (CFD) results, and model design and validation. However, PIV features a complex measurement chain with…

Fluid Dynamics · Physics 2021-07-07 Lalit K. Rajendran , Sayantan Bhattacharya , Sally P. M. Bane , Pavlos P. Vlachos

Cell tracking is a key computational task in live-cell microscopy, but fully automated analysis of high-throughput imaging requires reliable and, thus, uncertainty-aware data analysis tools, as the amount of data recorded within a single…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Richard D. Paul , Johannes Seiffarth , David Rügamer , Hanno Scharr , Katharina Nöh

We present a method that can simultaneously locate positions of overlapped multi-emitters at the theoretical-limit precision. We derive a set of simple equations whose solution gives the maximum likelihood estimator of multi-emitter…

Optics · Physics 2015-12-21 Yuto Ashida , Masahito Ueda

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…

The polarization of light conveys crucial information about the spatial ordering and optical properties of a specimen. However, precise polarization measurement in challenging conditions, including constrained spaces, low light levels, and…

Optics · Physics 2026-03-10 Martin Bielak , Dominik Vašinka , Miroslav Ježek

Point Spread Function (PSF) engineering is used in single emitter localization to measure the emitter position in 3D and possibly other parameters such as the emission color or dipole orientation as well. Advanced PSF models such as spline…

FRET-based approaches are a unique tool for sensing the immediate surroundings and interactions of (bio)molecules. FRET imaging and FLIM (Fluorescence Lifetime Imaging Microscopy) enable the visualization of the spatial distribution of…

MINFLUX microscopy allows for localization of fluorophores with nanometer precision using targeted scanning with an illumination profile with a minimum. However, current scanning patterns and the overall procedure are based on heuristics,…

Computational Physics · Physics 2026-04-17 Steffen Schultze , Helmut Grubmüller

Ptychography is a powerful imaging technique that is used in a variety of fields, including materials science, biology, and nanotechnology. However, the accuracy of the reconstructed ptychography image is highly dependent on the accuracy of…

Applied Physics · Physics 2024-06-03 Ming Du , Tao Zhou , Junjing Deng , Daniel J. Ching , Steven Henke , Mathew J. Cherukara

Measuring the lifetime of fluorescent emitters by time-correlated single photon counting (TCSPC) is a routine procedure in many research areas spanning from nanophotonics to biology. The precision of such measurement depends on the number…

Instrumentation and Detectors · Physics 2019-07-18 Dorian Bouchet , Valentina Krachmalnicoff , Ignacio Izeddin

Fiber orientation is decisive for the mechanical performance of composite materials. During manufacturing, variations in material and process parameters can influence fiber orientation. We employ multilevel polynomial surrogates to model…

Computational Engineering, Finance, and Science · Computer Science 2025-03-18 Stjepan Salatovic , Sebastian Krumscheid , Florian Wittemann , Luise Kärger
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