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Purpose: There is increasing interest in computed tomography (CT) image estimations from magnetic resonance (MR) images. The estimated CT images can be utilised for attenuation correction, patient positioning, and dose planning in…
Computed tomography (CT) is critical for various clinical applications, e.g., radiotherapy treatment planning and also PET attenuation correction. However, CT exposes radiation during acquisition, which may cause side effects to patients.…
The generation of synthetic CT (sCT) images from cone-beam CT (CBCT) data using deep learning methodologies represents a significant advancement in radiation oncology. This systematic review, following PRISMA guidelines and using the PICO…
Magnetic resonance imaging (MRI)-based synthetic computed tomography (sCT) simplifies radiation therapy treatment planning by eliminating the need for CT simulation and error-prone image registration, ultimately reducing patient radiation…
Generating synthetic CT (sCT) from MRI or CBCT plays a crucial role in enabling MRI-only and CBCT-based adaptive radiotherapy, improving treatment precision while reducing patient radiation exposure. To address this task, we adopt a fully…
Model-based treatment planning for transcranial ultrasound therapy typically involves mapping the acoustic properties of the skull from an x-ray computed tomography (CT) image of the head. Here, three methods for generating pseudo-CT images…
Currently, MRI-only radiotherapy (RT) eliminates some of the concerns about using CT images in RT chains such as the registration of MR images to a separate CT, extra dose delivery, and the additional cost of repeated imaging. However, one…
Quantifying normative pediatric cranial development and suture ossification is crucial for diagnosing and treating growth-related cephalic disorders. Computed tomography (CT) is widely used to evaluate cranial and sutural deformities;…
To enable magnetic resonance (MR)-only radiotherapy and facilitate modelling of radiation attenuation in humans, synthetic-CT (sCT) images need to be generated. Considering the application of MR-guided radiotherapy and online adaptive…
We develop here a semiparametric Gaussian mixture model (SGMM) for unsupervised learning with valuable spatial information taken into consideration. Specifically, we assume for each instance a random location. Then, conditional on this…
Synthetic CT image generation from MRI scan is necessary to create radiotherapy plans without the need of co-registered MRI and CT scans. The chosen baseline adversarial model with cycle consistency permits unpaired image-to-image…
Automatically generating one medical imaging modality from another is known as medical image translation, and has numerous interesting applications. This paper presents an interpretable generative modelling approach to medical image…
Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…
Providing more precise tissue attenuation information, synthetic computed tomography (sCT) generated from magnetic resonance imaging (MRI) contributes to improved radiation therapy treatment planning. In our study, we employ the advanced…
The ability to synthesise Computed Tomography images - commonly known as pseudo CT, or pCT - from MRI input data is commonly assessed using an intensity-wise similarity, such as an L2-norm between the ground truth CT and the pCT. However,…
Accurate targeting is critical for the effectiveness of transcranial focused ultrasound (tFUS) neuromodulation. While CT provides accurate skull acoustic properties, its ionizing radiation and poor soft tissue contrast limit clinical…
Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…
Computed tomography (CT) has been a powerful diagnostic tool since its emergence in the 1970s. Using CT data, three-dimensional (3D) structures of human internal organs and tissues, such as blood vessels, can be reconstructed using…
The aim of this paper is to develop a class of spatial transformation models (STM) to spatially model the varying association between imaging measures in a three-dimensional (3D) volume (or 2D surface) and a set of covariates. Our STMs…
Score-based generative models (SGMs) have recently shown promising results for image reconstruction on simulated positron emission tomography (PET) datasets. In this work we have developed and implemented practical methodology for 3D image…