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Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Bayesian methods constitute a popular approach for estimating the conditional independence structure in Gaussian graphical models, since they can quantify the uncertainty through the posterior distribution. Inference in this framework is…

Methodology · Statistics 2026-01-14 Marcus Gehrmann , Håkon Tjelmeland

Accurate synthesis of computed tomography (CT) images from magnetic resonance imaging (MRI) is clinically valuable for cranial applications such as attenuation correction, radiotherapy planning, and image-guided interventions. However,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Zhuoyao Xin , Yiren Zhang , Christopher Wu , Dong Liu , Chunming Gu , Elena Greco , Erik H. Middlebrooks , Jun Hua , Jia Guo

Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…

Medical Physics · Physics 2025-09-23 Alzahra Altalib , Chunhui Li , Alessandro Perelli

This paper presents a novel approach for learned synergistic reconstruction of medical images using multibranch generative models. Leveraging variational autoencoders (VAEs), our model learns from pairs of images simultaneously, enabling…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Noel Jeffrey Pinton , Alexandre Bousse , Catherine Cheze-Le-Rest , Dimitris Visvikis

Data augmentation can effectively resolve a scarcity of images when training machine-learning algorithms. It can make them more robust to unseen images. We present a lesion conditional Generative Adversarial Network LcGAN to generate…

Image and Video Processing · Electrical Eng. & Systems 2020-08-10 Manohar Karki , Junghwan Cho , Seokhwan Ko

Automated lesion segmentation from computed tomography (CT) is an important and challenging task in medical image analysis. While many advancements have been made, there is room for continued improvements. One hurdle is that CT images can…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Youbao Tang , Jinzheng Cai , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers

Fatigue crack growth is one of the most common types of deterioration in metal structures with significant implications on their reliability. Recent advances in Structural Health Monitoring (SHM) have motivated the use of structural…

Machine Learning · Statistics 2023-10-12 Nicholas E. Silionis , Konstantinos N. Anyfantis

The radiation dose in computed tomography (CT) examinations is harmful for patients but can be significantly reduced by intuitively decreasing the number of projection views. Reducing projection views usually leads to severe aliasing…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Bing Guan , Cailian Yang , Liu Zhang , Shanzhou Niu , Minghui Zhang , Yuhao Wang , Weiwen Wu , Qiegen Liu

Computed tomography (CT) is a beneficial imaging tool for diagnostic purposes. CT scans provide detailed information concerning the internal anatomic structures of a patient, but present higher radiation dose and costs compared to X-ray…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Benjamin Paulson , Joshua Goldshteyn , Sydney Balboni , John Cisler , Andrew Crisler , Natalia Bukowski , Julia Kalish , Theodore Colwell

Recent years have witnessed the emergence of 3D medical imaging techniques with the development of 3D sensors and technology. Due to the presence of noise in image acquisition, registration researchers focused on an alternative way to…

Machine Learning · Computer Science 2019-11-06 Liu Yang , Rudrasis Chakraborty

Dynamic total body positron emission tomography (TB-PET) makes it feasible to measure the kinetics of all organs in the body simultaneously which may lead to important applications in multi-organ disease and systems physiology. Since…

Medical Physics · Physics 2026-01-14 Yun Zhao , Qinlin Gu , Georgios I. Angelis , Andrew J. Reader , Yanan Fan , Steven R. Meikle

Using recent advances in generative artificial intelligence (AI) brought by diffusion models, this paper introduces a new synergistic method for spectral computed tomography (CT) reconstruction. Diffusion models define a neural network to…

Gaussian Splatting (GS) has emerged as a dominating technique for image rendering and has quickly been adapted for the X-ray Computed Tomography (CT) reconstruction task. However, despite being on par or better than many of its…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Pawel Tomasz Pieta , Rasmus Juul Pedersen , Sina Borgi , Jakob Sauer Jørgensen , Jens Wenzel Andreasen , Vedrana Andersen Dahl

Radiation therapy (RT) requires precise dose delivery over multiple fractions, with CT fundamental for treatment planning due to its electron density information. Repeated CT acquisitions impose radiation exposure and logistical burdens,…

We introduce the spiked mixture model (SMM) to address the problem of estimating a set of signals from many randomly scaled and noisy observations. Subsequently, we design a novel expectation-maximization (EM) algorithm to recover all…

Machine Learning · Statistics 2026-01-26 Paul-Louis Delacour , Sander Wahls , Jeffrey M. Spraggins , Lukasz Migas , Raf Van de Plas

The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…

Spatial generalized linear mixed models (SGLMMs) are popular and flexible models for non-Gaussian spatial data. They are useful for spatial interpolations as well as for fitting regression models that account for spatial dependence, and are…

Methodology · Statistics 2021-10-26 Yawen Guan , Murali Haran

Sparse-view computed tomography (CT) reduces radiation exposure by acquiring fewer projections, making it a valuable tool in clinical scenarios where low-dose radiation is essential. However, this often results in increased noise and…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Yingtai Li , Xueming Fu , Han Li , Shang Zhao , Ruiyang Jin , S. Kevin Zhou

In this letter, we propose a Gaussian mixture model (GMM)-based channel estimator which is learned on imperfect training data, i.e., the training data are solely comprised of noisy and sparsely allocated pilot observations. In a practical…

Signal Processing · Electrical Eng. & Systems 2023-02-14 Benedikt Fesl , Nurettin Turan , Michael Joham , Wolfgang Utschick