Related papers: Optimal Trajectories of Brain State Transitions
The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…
Criticality is hypothesized as a physical mechanism underlying efficient transitions between cortical states and remarkable information processing capacities in the brain. While considerable evidence generally supports this hypothesis,…
The brain is in a state of perpetual reverberant neural activity, even in the absence of specific tasks or stimuli. Shedding light on the origin and functional significance of such a dynamical state is essential to understanding how the…
The fundamental, powerful process of computation in the brain has been widely misunderstood. The paper [1] associates the general failure to build intelligent thinking machines with current reductionist principles of temporal coding and…
Here we describe an "information based exchange" model of brain function that ascribes to neocortex, basal ganglia, and thalamus distinct network functions. The model allows us to analyze whole brain system set point measures, such as the…
Cognitive states are involving in our daily life, which motivates us to explore them and understand them by a vast variety of perspectives. Among these perspectives, brain connectivity is increasingly receiving attention in recent years. It…
The activity patterns of highly developed cognitive systems like the human brain are dominated by autonomous dynamical processes, that is by a self-sustained activity which would be present even in the absence of external sensory stimuli.…
The question of controllability of natural and man-made network systems has recently received considerable attention. In the context of the human brain, the study of controllability may not only shed light into the organization and function…
When viewed at a certain coarse grain, the brain seems a relatively small dynamical system composed by a few dozen interacting areas, performing a number of stereotypical behaviors. It is known that, even relatively small dynamical systems…
Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics…
Understanding emotional processing in the human brain requires examining the complex interactions between different brain regions. While previous studies have identified specific regions involved in emotion processing, a holistic network…
The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…
A large repertoire of spatiotemporal activity patterns in the brain is the basis for adaptive behaviour. Understanding the mechanism by which the brain's hundred billion neurons and hundred trillion synapses manage to produce such a range…
The brain is a highly complex organ consisting of a myriad of subsystems that flexibly interact and adapt over time and context to enable perception, cognition, and behavior. Understanding the multi-scale nature of the brain, i.e., how…
Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…
Spontaneous brain activity generically displays transient spatiotemporal coherent structures, which can selectively be affected in various neurological and psychiatric pathologies. Here we model the full brain's electroencephalographic…
The human brain exhibits a relatively stable spatiotemporal organization that supports brain function and can be manipulated via local brain stimulation. Such perturbations to local cortical dynamics are globally integrated by distinct…
The objective of this paper is to review physiological and computational aspects of the responsiveness of the cerebral cortex to stimulation, and how responsiveness depends on the state of the system. This correspondence between brain state…
Understanding how neural dynamics shape cognitive experiences remains a central challenge in neuroscience and psychiatry. Here, we present a novel framework leveraging state-to-output controllability from dynamical systems theory to model…
Pain is among the most salient of experiences while also, curiously, being among the most malleable. A large body of research has revealed that a multitude of explicit strategies can be used to effectively alter the attention-demanding…