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Although random cell complexes occur throughout the physical sciences, there does not appear to be a standard way to quantify their statistical similarities and differences. The various proposals in the literature are usually motivated by…

Computational Geometry · Computer Science 2016-06-15 Benjamin Schweinhart , Jeremy Mason , Robert MacPherson

Speech production requires the rapid coordination of a complex hierarchy of linguistic units, transforming a semantic representation into a precise sequence of articulatory movements. To unravel the neural mechanisms underlying this feat,…

Neurons and Cognition · Quantitative Biology 2026-04-06 Julien Gadonneix , Mingfang Zhang , Jérémy Rapin , Linnea Evanson , Pierre Bourdillon , Jean-Rémi King

The gap between the huge volumes of data needed to train artificial neural networks and the relatively small amount of data needed by their biological counterparts is a central puzzle in machine learning. Here, inspired by biological…

Disordered Systems and Neural Networks · Physics 2022-04-19 Miriam Aquaro , Francesco Alemanno , Ido Kanter , Fabrizio Durante , Elena Agliari , Adriano Barra

Neuronal systems need to process temporal signals. We here show how higher-order temporal (co-)fluctuations can be employed to represent and process information. Concretely, we demonstrate that a simple biologically inspired feedforward…

Neurons and Cognition · Quantitative Biology 2023-09-13 Sandra Nestler , Moritz Helias , Matthieu Gilson

This paper targets the problem of encoding information into binary cell assemblies. Spiking neural networks and k-winners-take-all models are two common approaches, but the first is hard to use for information processing and the second is…

Neural and Evolutionary Computing · Computer Science 2021-08-03 Viacheslav Osaulenko , Danylo Ulianych

In the self-assembly process which drives the formation of cellular membranes, micelles, and capsids, a collection of separated subunits spontaneously binds together to form functional and more ordered structures. In this work, we study the…

Biological Physics · Physics 2021-05-04 Mobolaji Williams

Hyperuniform materials, characterized by their suppressed density fluctuations and vanishing structure factors as the wave number approaches zero, represent a unique state of matter that straddles the boundary between order and randomness.…

Disordered Systems and Neural Networks · Physics 2024-08-20 Yiwen Tang , Xinzhi Li , Dapeng Bi

Correlations among spikes, both on the same neuron and across neurons, are ubiquitous in the brain. For example cross-correlograms can have large peaks, at least in the periphery, and smaller -- but still non-negligible -- ones in cortex,…

Neurons and Cognition · Quantitative Biology 2011-09-30 Peter E. Latham , Yasser Roudi

We apply an information theoretic treatment of action potential time series measured with microelectrode arrays to estimate the connectivity of mammalian neuronal cell assemblies grown {\it in vitro}. We infer connectivity between two…

Neurons and Cognition · Quantitative Biology 2007-05-23 Luis M. A. Bettencourt , Greg J. Stephens , Michael I. Ham , Guenter W. Gross

In this paper, a multi-scale approach to spectrum sensing in cognitive cellular networks is proposed. In order to overcome the huge cost incurred in the acquisition of full network state information, a hierarchical scheme is proposed, based…

Information Theory · Computer Science 2017-02-28 Nicolo Michelusi , Matthew Nokleby , Urbashi Mitra , Robert Calderbank

Despite tremendous progress in neuroscience, we do not have a compelling narrative for the precise way whereby the spiking of neurons in our brain results in high-level cognitive phenomena such as planning and language. We introduce a…

Neural and Evolutionary Computing · Computer Science 2025-07-17 Daniel Mitropolsky , Christos Papadimitriou

We introduce a new concept of a subgraph class called a superbubble for analyzing assembly graphs, and propose an efficient algorithm for detecting it. Most assembly algorithms utilize assembly graphs like the de Bruijn graph or the overlap…

Data Structures and Algorithms · Computer Science 2013-08-02 Taku Onodera , Kunihiko Sadakane , Tetsuo Shibuya

The modular and hierarchical organization of the brain is believed to support the coexistence of segregated (specialization) and integrated (binding) information processes. A relevant question is yet to understand how such architecture…

Neurons and Cognition · Quantitative Biology 2025-06-19 Raphaël Bergoin , Alessandro Torcini , Gustavo Deco , Mathias Quoy , Gorka Zamora-López

Despite substantial potential to transform bioscience, medicine, and bioengineering, whole-cell models remain elusive. One of the biggest challenges to whole-cell models is assembling the large and diverse array of data needed to model an…

Quantitative Methods · Quantitative Biology 2021-05-25 Yin Hoon Chew , Jonathan R. Karr

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

Compositionality is a key property for dealing with complexity, which has been studied from many points of view in diverse fields. Particularly, the composition of individual computations (or programs) has been widely studied almost since…

Logic in Computer Science · Computer Science 2022-06-06 Damian Arellanes

This paper describes a relatively simple way of allowing a brain model to self-organise its concept patterns through nested structures. Time is a key element and a simulator would be able to show how patterns may form and then fire in…

Neural and Evolutionary Computing · Computer Science 2014-09-05 Kieran Greer

In this paper, we review existing points-to Separation Logics for dynamic memory reasoning and we find that different usages of heap separation tend to be an obstacle. Hence, two total and strict spatial heap operations are proposed upon…

Logic in Computer Science · Computer Science 2019-05-31 René Haberland , Kirill Krinkin

The evaluation of the performance of clustered cooperative beamforming in cellular networks generally requires the solution of complex non-convex optimization problems. In this letter, a framework based on a hypergraph formalism is proposed…

Information Theory · Computer Science 2015-10-22 Bahar Azari , Osvaldo Simeone , Umberto Spagnolini , Antonia M. Tulino

A definition for a class of asynchronous cellular arrays is proposed. An example of such asynchrony would be independent Poisson arrivals of cell iterations. The Ising model in the continuous time formulation of Glauber falls into this…

Distributed, Parallel, and Cluster Computing · Computer Science 2007-05-23 Boris D. Lubachevsky