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Many types of peripheral and transmembrane proteins can sense and generate membrane curvature. Laterally isotropic proteins and crescent proteins with twofold rotational symmetry, such as Bin/Amphiphysin/Rvs superfamily proteins, have been…

Soft Condensed Matter · Physics 2024-02-12 Hiroshi Noguchi

Integral membrane proteins deform the surrounding bilayer creating long-ranged forces that influence distant proteins. These forces can be attractive or repulsive, depending on the proteins' shape, height, contact angle with the bilayer, as…

Statistical Mechanics · Physics 2007-05-23 Tom Chou , Ken S. Kim , George Oster

Insulated cantilever probes with a high aspect ratio conducting apex have been fabricated and their dynamic and electrical properties analyzed. The cantilevers were coated with silicon dioxide and a via was fabricated through the oxide at…

Materials Science · Physics 2008-03-13 B. J. Rodriguez , S. Jesse , K. Seal , A. P. Baddorf , S. V. Kalinin , P. Rack

High purity epitaxial FeSe0.5Te0.5 thin films with different thickness were grown by Pulsed Laser Ablation on different substrates. By varying the film thickness, Tc up to 21K were observed, significantly larger than the bulk value.…

Simulations based on experimental data obtained from multifragmenting quasifused nuclei produced in central 129Xe + natSn collisions have been used to deduce event by event freeze-out properties on the thermal excitation energy range 4-12…

The endoplasmic reticulum (ER), a cellular organelle that forms a cell-spanning network of tubes and sheets, is an important location of protein synthesis and folding. When the ER experiences sustained unfolded protein stress, IRE1 proteins…

Biological Physics · Physics 2023-05-02 Liam T Kischuck , Aidan I Brown

A principal component analysis (PCA) of clean microcalorimeter pulse records can be a first step beyond statistically optimal linear filtering of pulses towards a fully non-linear analysis. For PCA to be practical on spectrometers with…

Data Analysis, Statistics and Probability · Physics 2020-01-08 J. W. Fowler , B. K. Alpert , Y. -I. Joe , G. C. O'Neil , D. S. Swetz , J. N. Ullom

This paper presents a comprehensive analytical and simulation-based study of curved electrode geometries for enhancing the sensitivity of MEMS capacitive accelerometers. Expressions for the capacitance between a planar movable electrode and…

Systems and Control · Electrical Eng. & Systems 2025-08-19 Adhinarayan Naembin Ashok , Adarsh Ganesan

Iron-based compounds (IBS) display a surprising variety of superconducting properties that seems to arise from the strong sensitivity of these systems to tiny details of the lattice structure. In this respect, systems that become…

We examine the ground state properties of the s=1/2 transverse Ising chain with regularly alternating bonds and fields using exact analytical results and exact numerical data for long (up to N=900) and short (N=20) chains. For a given…

Condensed Matter · Physics 2009-11-07 Oleg Derzhko , Johannes Richter , Taras Krokhmalskii , Oles' Zaburannyi

Atomic motions and energetics for a phosphate transfer reaction catalyzed by the cAMP-dependent protein kinase (PKA) are calculated by plane-wave density functional theory, starting from structures of proteins crystallized in both the…

Aptamers are single stranded DNA, RNA or peptide sequences having the ability to bind a variety of specific targets (proteins, molecules as well as ions). Therefore, aptamer production and selection for therapeutic and diagnostic…

Biomolecules · Quantitative Biology 2018-01-04 R. Cataldo , E. Alfinito , L. Reggiani

The flare activity of the Sun has been studied for decades, using both space- and ground-based telescopes. In particular, the Interface Region Imaging Spectrograph (IRIS) provides unique diagnostics to investigate the thermodynamics of…

Solar and Stellar Astrophysics · Physics 2022-11-11 Alberto Sainz Dalda , Bart De Pontieu

In the post-genome era, biologists have sought to measure the complete complement of proteins, termed proteomics. Currently, the most effective method to measure the proteome is with shotgun, or bottom-up, proteomics, in which the proteome…

Genomics · Quantitative Biology 2018-11-30 Jesse G. Meyer

The study of protein interactions has generated great interest in the food industry. Therefore, research on new supramolecular structures shows promise. Supramolecular structures of the whey proteins {\alpha}-lactalbumin and…

In 1999 Wright and Dyson highlighted the fact that large sections of the proteome of all organisms are comprised of protein sequences that lack globular folded structures under physiological conditions. Since then the biophysics community…

Biological Physics · Physics 2024-09-05 Zi Hao Liu , Maria Tsanai , Oufan Zhang , Julie Forman-Kay , Teresa Head-Gordon

A Profile Mixture Model is a model of protein evolution, describing sequence data in which sites are assumed to follow many related substitution processes on a single evolutionary tree. The processes depend in part on different amino acid…

Populations and Evolution · Quantitative Biology 2020-07-07 Samaneh Yourdkhani , Elizabeth S. Allman , John A. Rhodes

The synthesis and properties of LiFeAs, a high-Tc Fe-based superconducting stoichiometric compound, are reported. Single crystal x-ray studies reveal that it crystallizes in the tetragonal PbFCl type (P4/nmm) with a=3.7914(7) A and…

Superconductivity · Physics 2008-08-25 Joshua H. Tapp , Zhongjia Tang , Bing Lv , Kalyan Sasmal , Bernd Lorenz , Paul C. W. Chu , Arnold M. Guloy

Proteinoids are solidified gels made from poly(amino acids) based polymers that exhibit oscillatory electrical activity. It has been proposed that proteinoids are capable of performing analog computing as their electrical activity can be…

Under dehydration conditions, amphipathic Late Embryogenesis Abundant (LEA) proteins fold spontaneously from a random conformation into alpha-helical structures and this transition is promoted by the presence of membranes. To gain insight…

Biological Physics · Physics 2012-06-27 Sergey Pogodin , Nigel K. H. Slater , Vladimir A. Baulin