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Polymerization dynamics of single actin filaments is investigated theoretically using a stochastic model that takes into account the hydrolysis of ATP-actin subunits, the geometry of actin filament tips, the lateral interactions between the…

Soft Condensed Matter · Physics 2009-11-11 Evgeny B. Stukalin , Anatoly B. Kolomeisky

Mixing of two fluids can lead to the formation of a precipitate. If one of the fluids is injected into a confined space filled with the other, a created precipitate disrupts the flow locally and forms complex spatiotemporal patterns. The…

Soft Condensed Matter · Physics 2023-12-12 Shunsuke Tanaka , Kojiro Otoguro , Miyuki Kunihiro , Hiroki Ishikawa , Yutaka Sumino

The entropic force exerted by the Brownian fluctuations of a grafted semiflexible polymer upon a rigid smooth wall are calculated both analytically and by Monte Carlo simulations. Such forces are thought to play an important role for…

Soft Condensed Matter · Physics 2007-05-23 Azam Gholami , Jan Wilhelm , Erwin Frey

Protein molecules often self-assemble by means of non-covalent physical bonds to form extended filaments, such as amyloids, F-actin, intermediate filaments, and many others. The kinetics of filament growth is limited by the disassembly…

Soft Condensed Matter · Physics 2015-03-24 A. Zaccone , I. Terentjev , L. DiMichele , E. M. Terentjev

Polymerization of dendritic actin networks underlies important mechanical processes in cell biology such as the protrusion of lamellipodia, propulsion of growth cones in dendrites of neurons, intracellular transport of organelles and…

Biological Physics · Physics 2021-03-17 Rohan Abeyaratne , Prashant K. Purohit

We present a novel flow instability that can arise in thin films of cytoskeletal fluids if the friction with the substrate on which the film lies is sufficiently strong. We consider a two dimensional, membrane-bound fragment containing…

Soft Condensed Matter · Physics 2009-11-13 A. C. Callan-Jones , J. -F. Joanny , J. Prost

The fracture and severing of polymer chains plays a critical role in the failure of fibrous materials and the regulated turnover of intracellular filaments. Using continuum wormlike chain models, we investigate the fracture of semiflexible…

Statistical Mechanics · Physics 2020-03-05 Alexander Lorenzo , Enrique M. De La Cruz , Elena F. Koslover

We examine fluctuation-induced (pseudo-Casimir) interactions in nematic liquid-crystalline films confined between two surfaces, where one of the surfaces imposes a strong homeotropic anchoring (ensuring a uniform mean director profile),…

Soft Condensed Matter · Physics 2015-06-22 Fahimeh Karimi Pour Haddadan , Ali Naji , Nafiseh Shirzadiani , Rudolf Podgornik

We study theoretically the complex network of forces that is responsible for the static structure and properties of granular materials. We present detailed calculations for a model in which the fluctuations in the force distribution arise…

Condensed Matter · Physics 2009-10-28 S. N. Coppersmith , C. -h. Liu , S. Majumdar , O. Narayan , T. A. Witten

Competition for resources is a fundamental constraint that guides the self-organization of natural, biological, and human systems, ranging from urban planning and ecosystem development to intracellular pattern formation. Here, we reveal…

The process of force generation by the growth of biopolymers is simulated via a Langevin-dynamics approach. The interaction forces are taken to have simple forms that favor the growth of straight fibers from solution. The force-velocity…

Biological Physics · Physics 2009-11-06 A. E. Carlsson

We analyze the non-equilibrium shape fluctuations of giant unilamellar vesicles encapsulating motile bacteria. Owing to bacteria--membrane collisions, we experimentally observe a significant increase in the magnitude of membrane…

Soft Condensed Matter · Physics 2020-04-22 Sho C. Takatori , Amaresh Sahu

Many of the cell membrane vital functions are achieved by the self-organization of the proteins and biopolymers embedded in it. The protein dynamics are in part determined by its drag. A large number of these proteins can polymerize to form…

Fluid Dynamics · Physics 2023-09-13 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

The actin cytoskeleton in living cells generates forces in conjunction with myosin motor proteins to directly and indirectly drive essential cellular processes. The semiflexible filaments of the cytoskeleton can respond nonlinearly to the…

Soft Condensed Matter · Physics 2019-12-19 D. Mizuno , C. Tardin , C. F. Schmidt

The polymerization of actin via branching at a cell membrane containing nucleation-promoting factors is simulated using a stochastic-growth methodology. The polymerized-actin distribution displays three types of behavior: a) traveling…

Biological Physics · Physics 2015-05-19 Anders E. Carlsson

Non-linear simulations of filament propagation in a realistic MAST SOL flux tube geometry using the BOUT++ fluid modelling framework show an isolation of the dynamics of the filament in the divertor region from the midplane region due to…

Plasma Physics · Physics 2015-06-16 Nicholas Walkden , Benjamin Dudson , Geoff Fishpool

Active force generation by actin-myosin cortex coupled to the cell membrane allows the cell to deform, respond to the environment, and mediate cell motility and division. Several membrane-bound activator proteins move along it and couple to…

Soft Condensed Matter · Physics 2021-12-23 Subhadip Ghosh , Sashideep Gutti , Debasish Chaudhuri

We probed the bending of actin subject to external forcing and viscous drag. Single actin filaments were moved perpendicular to their long axis in an oscillatory way by means of an optically tweezed latex bead attached to one end of the…

Soft Condensed Matter · Physics 2009-10-30 D. Riveline , Chris H. Wiggins , A. Ott , Raymond E. Goldstein

Cell shape changes are largely controlled by the actin cytoskeleton, a dynamic filament network beneath the plasma membrane. Several cell types can form extended free-standing protrusions not supported by an extracellular substrate or…

Soft Condensed Matter · Physics 2025-10-21 Kristiana Mihali , Dennis Wörthmüller , Pierre Sens

A recent work of Harikrishnan et al. [arXiv:2110.02253 (2021)] has revealed an abundance of hairpin-like vortex structures, oriented in a similar direction, in the turbulent patches of a stably stratified Ekman flow. The Ekman flow over a…

Fluid Dynamics · Physics 2023-07-25 Abhishek Harikrishnan , Marie Rodal , Rupert Klein , Daniel Margerit , Nikki Vercauteren