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The advent of next-generation sequencing (NGS) has revolutionized genomic research by enabling cost-effective, high-throughput sequencing of a diverse range of organisms. This breakthrough has unleashed a "Cambrian explosion" in genomic…

Genomic data sets are growing dramatically as the cost of sequencing continues to decline and small sequencing devices become available. Enormous community databases store and share this data with the research community, but some of these…

Modern clustering approaches often trade interpretability for performance, particularly in deep learning-based methods. We present Generative Kernel Spectral Clustering (GenKSC), a novel model combining kernel spectral clustering with…

Machine Learning · Computer Science 2025-04-25 David Winant , Sonny Achten , Johan A. K. Suykens

This chapter aims to provide next-level understanding of the problems of the world and the solutions available to those problems, which lie very well within the domain of neural computing, and at the same time are intelligent in their…

Neural and Evolutionary Computing · Computer Science 2021-07-07 Ayushe Gangal , Peeyush Kumar , Sunita Kumari , Aditya Kumar

In the last decade the broad scope of complex networks has led to a rapid progress. In this area a particular interest has the study of community structures. The analysis of this type of structure requires the formalization of the intuitive…

Information Retrieval · Computer Science 2009-12-07 Vincenza Carchiolo , Alessandro Longheu , Michele Malgeri , Giuseppe Mangioni

Recent advances in high-throughput genomics technologies have resulted in the sequencing of large numbers of (near) complete genomes. These genome sequences are being mined for important functional elements, such as genes. They are also…

Genomics · Quantitative Biology 2007-05-23 Lior Pachter

Precision medicine aims for personalized prognosis and therapeutics by utilizing recent genome-scale high-throughput profiling techniques, including next-generation sequencing (NGS). However, translating NGS data faces several challenges.…

Many biological data analysis processes like Cytometry or Next Generation Sequencing (NGS) produce massive amounts of data which needs to be processed in batches for down-stream analysis. Such datasets are prone to technical variations due…

Machine Learning · Computer Science 2019-06-24 Uddeshya Upadhyay , Arjun Jain

The Next Generation Networks (NGN) aims to integrate for IP-based telecom infrastructures and provide most advance & high speed emerging value added services. NGN capable to provide higher innovative services, these services will able to…

Networking and Internet Architecture · Computer Science 2011-11-10 Kamaljit I. Lakhtaria , Dhinaharan Nagamalai

The groundbreaking performance of deep neural networks (NNs) promoted a surge of interest in providing a mathematical basis to deep learning theory. Low-rank tensor decompositions are specially befitting for this task due to their close…

Machine Learning · Computer Science 2025-12-18 Ricardo Borsoi , Konstantin Usevich , Marianne Clausel

Deep neural networks (DNNs) have become an enabling component for a myriad of artificial intelligence applications. DNNs have shown sometimes superior performance, even compared to humans, in cases such as self-driving, health applications,…

Neural and Evolutionary Computing · Computer Science 2023-07-12 Ghada Alsuhli , Vasileios Sakellariou , Hani Saleh , Mahmoud Al-Qutayri , Baker Mohammad , Thanos Stouraitis

The tens of millions of radio sources to be detected with next-generation surveys pose new challenges, quite apart from the obvious ones of processing speed and data volumes. For example, existing algorithms are inadequate for source…

Instrumentation and Methods for Astrophysics · Physics 2017-06-14 Ray P. Norris

Medical data mainly includes various types of biomedical signals and medical images, which can be used by professional doctors to make judgments on patients' health conditions. However, the interpretation of medical data requires a lot of…

Neural and Evolutionary Computing · Computer Science 2023-08-15 X. Li , X. Zhang , X. Yi , D. Liu , H. Wang , B. Zhang , B. Zhang , D. Zhao , L. Wang

The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this…

Cryptography and Security · Computer Science 2022-02-11 Sara Jafarbeiki , Raj Gaire , Amin Sakzad , Shabnam Kasra Kermanshahi , Ron Steinfeld

High throughput sequencing (HTS)-based technology enables identifying and quantifying non-culturable microbial organisms in all environments. Microbial sequences have enhanced our understanding of the human microbiome, the soil and plant…

Applications · Statistics 2021-03-09 Pratheepa Jeganathan , Susan P. Holmes

RNA-sequencing (RNA-seq) has become an exemplar technology in modern biology and clinical applications over the past decade. It has gained immense popularity in the recent years driven by continuous efforts of the bioinformatics community…

Sequencing by Emergence (SEQE) is a new single-molecule nucleic acid (DNA/RNA) sequencing technology that estimates sequence as an emergent property of the binding and localization of a repertoire of short oligonucleotide probes. SEQE…

Genomics · Quantitative Biology 2021-08-04 Nicholas Boyd , Samuel Woodhouse , Kalim Mir

Sequence labeling (SL) is a fundamental research problem encompassing a variety of tasks, e.g., part-of-speech (POS) tagging, named entity recognition (NER), text chunking, etc. Though prevalent and effective in many downstream applications…

Computation and Language · Computer Science 2020-11-16 Zhiyong He , Zanbo Wang , Wei Wei , Shanshan Feng , Xianling Mao , Sheng Jiang

Signal processing is a fundamental component of almost any sensor-enabled system, with a wide range of applications across different scientific disciplines. Time series data, images, and video sequences comprise representative forms of…

In the past several years, we have taken advantage of a number of opportunities to advance the intersection of next generation high-performance computing AI and big data technologies through partnerships in precision medicine. Today we are…

Artificial Intelligence · Computer Science 2018-05-11 Edmon Begoli , Jim Brase , Bambi DeLaRosa , Penelope Jones , Dimitri Kusnezov , Jason Paragas , Rick Stevens , Fred Streitz , Georgia Tourassi