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Notable progress has been made in generalist medical large language models across various healthcare areas. However, large-scale modeling of in-hospital time series data - such as vital signs, lab results, and treatments in critical care -…

While randomized controlled trials (RCTs) are the gold-standard for establishing the efficacy and safety of a medical treatment, real-world evidence (RWE) generated from real-world data (RWD) has been vital in post-approval monitoring and…

Machine learning (ML) approaches have demonstrated promising results in a wide range of healthcare applications. Data plays a crucial role in developing ML-based healthcare systems that directly affect people's lives. Many of the ethical…

The time series cluster kernel (TCK) provides a powerful tool for analysing multivariate time series subject to missing data. TCK is designed using an ensemble learning approach in which Bayesian mixture models form the base models. Because…

Machine Learning · Computer Science 2019-07-12 Karl Øyvind Mikalsen , Cristina Soguero-Ruiz , Filippo Maria Bianchi , Arthur Revhaug , Robert Jenssen

Clinical and biomedical research in low-resource settings often faces significant challenges due to the need for high-quality data with sufficient sample sizes to construct effective models. These constraints hinder robust model training…

With the widespread of machine learning models for healthcare applications, there is increased interest in building applications for personalized medicine. Despite the plethora of proposed research for personalized medicine, very few focus…

Machine Learning · Computer Science 2024-02-27 Ghadeer O. Ghosheh , Jin Li , Tingting Zhu

Machine learning is used in medicine to support physicians in examination, diagnosis, and predicting outcomes. One of the most dynamic area is the usage of patient generated health data from intensive care units. The goal of this paper is…

Precision Medicine (PM) is an emerging approach that appears with the impression of changing the existing paradigm of medical practice. Recent advances in technological innovations and genetics, and the growing availability of health data…

Computers and Society · Computer Science 2019-11-05 Muhammad Afzal , S. M. Riazul Islam , Maqbool Hussain , Sungyoung Lee

A large fraction of the electronic health records (EHRs) consists of clinical measurements collected over time, such as lab tests and vital signs, which provide important information about a patient's health status. These sequences of…

Machine Learning · Statistics 2020-03-02 Karl Øyvind Mikalsen , Cristina Soguero-Ruiz , Robert Jenssen

The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has…

Machine Learning · Computer Science 2026-04-30 Yunkun Zhang , Jin Gao , Zheling Tan , Lingfeng Zhou , Kexin Ding , Mu Zhou , Shaoting Zhang , Dequan Wang

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Product Data Management (PDM) claims of producing desktop and web based systems to maintain the organizational data to increase the quality of products by improving the process of development, business process flows, change management,…

Other Computer Science · Computer Science 2010-08-10 Zeeshan Ahmed , Detlef Gerhard

Advancements in sensing and computing technologies, the development of human and computer interaction frameworks, big data storage capabilities, and the emergence of cloud storage and could computing have resulted in an abundance of data in…

Machine Learning · Computer Science 2020-07-07 Ramin Moradi , Katrina M. Groth

We introduce the world's first clinical terminology for the Chinese healthcare community, namely MedCT, accompanied by a clinical foundation model MedBERT and an entity linking model MedLink. The MedCT system enables standardized and…

Computation and Language · Computer Science 2025-04-11 Ye Chen , Dongdong Huang , Haoyun Xu , Cong Fu , Lin Sheng , Qingli Zhou , Yuqiang Shen , Kai Wang

Requirements engineering is known to be a key factor for the success of software projects. Inside this discipline, goal-oriented requirements engineering approaches have shown specially suitable to deal with projects where it is necessary…

Software Engineering · Computer Science 2009-06-18 Cristina Cachero , Jesús Pardillo

Background: Access to medical care is strongly dependent on resource allocation, such as the geographical distribution of medical facilities. Nevertheless, this data is usually restricted to country official documentation, not available to…

Artificial Intelligence · Computer Science 2022-09-27 Selene Baez Santamaria , Emmanouil Manousogiannis , Guusje Boomgaard , Linh P. Tran , Zoltan Szlavik , Robert-Jan Sips

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

With the digitization of health data, the growth of electronic health and medical records lowers barriers for using algorithmic techniques for data analysis. While classical machine learning techniques for health data approach…

Quantum Physics · Physics 2025-05-09 Riddhi S. Gupta , Carolyn E. Wood , Teyl Engstrom , Jason D. Pole , Sally Shrapnel

Distributed representations of medical concepts have been used to support downstream clinical tasks recently. Electronic Health Records (EHR) capture different aspects of patients' hospital encounters and serve as a rich source for…

Computation and Language · Computer Science 2020-01-07 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Traditional diagnosis of chronic diseases involves in-person consultations with physicians to identify the disease. However, there is a lack of research focused on predicting and developing application systems using clinical notes and blood…

Software Engineering · Computer Science 2024-06-27 Chun-Chieh Liao , Wei-Ting Kuo , I-Hsuan Hu , Yen-Chen Shih , Jun-En Ding , Feng Liu , Fang-Ming Hung
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