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Persistent homology is a powerful mathematical tool that summarizes useful information about the shape of data allowing one to detect persistent topological features while one adjusts the resolution. However, the computation of such…

Quantum Physics · Physics 2022-03-01 Bernardo Ameneyro , Vasileios Maroulas , George Siopsis

Persistent homology is a common technique in topological data analysis providing geometrical and topological information about the sample space. All this information, known as topological features, is summarized in persistence diagrams, and…

Methodology · Statistics 2022-04-05 Asael Fabian Martínez

An Important tool in the field topological data analysis is known as persistent Homology (PH) which is used to encode abstract representation of the homology of data at different resolutions in the form of persistence diagram (PD). In this…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Aras Asaad , Dashti Ali , Taban Majeed , Rasber Rashid

In recent years, cosmic shear has emerged as a powerful tool to study the statistical distribution of matter in our Universe. Apart from the standard two-point correlation functions, several alternative methods like peak count statistics…

Cosmology and Nongalactic Astrophysics · Physics 2021-04-21 Sven Heydenreich , Benjamin Brück , Joachim Harnois-Déraps

The field of mathematical morphology offers well-studied techniques for image processing. In this work, we view morphological operations through the lens of persistent homology, a tool at the heart of the field of topological data analysis.…

Computational Geometry · Computer Science 2021-03-25 Yu-Min Chung , Sarah Day , Chuan-Shen Hu

Skin cancer is one of the most common cancers in the United States. As technological advancements are made, algorithmic diagnosis of skin lesions is becoming more important. In this paper, we develop algorithms for segmenting the actual…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Yu-Min Chung , Chuan-Shen Hu , Austin Lawson , Clifford Smyth

Persistent homology is a popular computational tool for analyzing the topology of point clouds, such as the presence of loops or voids. However, many real-world datasets with low intrinsic dimensionality reside in an ambient space of much…

Machine Learning · Computer Science 2024-11-01 Sebastian Damrich , Philipp Berens , Dmitry Kobak

We characterize structures such as monotonicity, convexity, and modality in smooth regression curves using persistent homology. Persistent homology is a key tool in topological data analysis that detects higher-dimensional topological…

Algebraic Topology · Mathematics 2025-10-28 Satish Kumar , Subhra Sankar Dhar

Biomolecular structure comparison not only reveals evolutionary relationships, but also sheds light on biological functional properties. However, traditional definitions of structure or sequence similarity always involve superposition or…

Quantitative Methods · Quantitative Biology 2017-07-13 Kelin Xia

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

Persistent homology is a popular tool in Topological Data Analysis. It provides numerical characteristics of data sets which reflect global geometric properties. In order to be useful in practice, for example for feature generation in…

Computational Geometry · Computer Science 2020-02-17 Boris Goldfarb

Accurate and interpretable brain tumor classification from medical imaging remains a challenging problem due to the high dimensionality and complex structural patterns present in magnetic resonance imaging (MRI). In this study, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Faisal Ahmed

We propose a flexible algorithm for feature detection and hypothesis testing in images with ultra low signal-to-noise ratio using cubical persistent homology. Our main application is in the identification of atomic columns and other…

Applications · Statistics 2023-01-19 Andrew M. Thomas , Peter A. Crozier , Yuchen Xu , David S. Matteson

Extracting useful information from large data sets can be a daunting task. Topological methods for analyzing data sets provide a powerful technique for extracting such information. Persistent homology is a sophisticated tool for identifying…

Quantum Physics · Physics 2015-12-17 Seth Lloyd , Silvano Garnerone , Paolo Zanardi

In this paper we present a methodology of classifying hepatic (liver) lesions using multidimensional persistent homology, the matching metric (also called the bottleneck distance), and a support vector machine. We present our classification…

Computer Vision and Pattern Recognition · Computer Science 2012-10-03 Aaron Adcock , Daniel Rubin , Gunnar Carlsson

Long lived topological features are distinguished from short lived ones (considered as topological noise) in simplicial complexes constructed from complex networks. A new topological invariant, persistent homology, is determined and…

Mathematical Physics · Physics 2009-11-13 Danijela Horak , Slobodan Maletic , Milan Rajkovic

In this study, we present a novel molecular fingerprint generation method based on multiparameter persistent homology. This approach reveals the latent structures and relationships within molecular geometry, and detects topological features…

Biomolecules · Quantitative Biology 2023-11-21 Andac Demir , Bulent Kiziltan

In this paper we study a new metric for comparing Betti numbers functions in bidimensional persistent homology, based on coherent matchings, i.e. families of matchings that vary in a continuous way. We prove some new results about this…

Algebraic Topology · Mathematics 2018-05-29 Andrea Cerri , Marc Ethier , Patrizio Frosini

Recently, persistent homology has had tremendous success in biomolecular data analysis. It works by examining the topological relationship or connectivity of a group of atoms in a molecule at a variety of scales, then rendering a family of…

Biomolecules · Quantitative Biology 2019-03-27 David Bramer , Guo-Wei Wei

In dermoscopic images, which allow visualization of surface skin structures not visible to the naked eye, lesion shape offers vital insights into skin diseases. In clinically practiced methods, asymmetric lesion shape is one of the criteria…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 M. A. Rasel , Sameem Abdul Kareem , Zhenli Kwan , Nik Aimee Azizah Faheem , Winn Hui Han , Rebecca Kai Jan Choong , Shin Shen Yong , Unaizah Obaidellah
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