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Sequential data collection has emerged as a widely adopted technique for enhancing the efficiency of data gathering processes. Despite its advantages, such data collection mechanism often introduces complexities to the statistical inference…
In observational studies, accurately characterizing variance is critical for sample size determination, yet unaccounted-for variability from propensity score estimation and the resulting weights limit the accuracy of standard variance…
Retrieval-Augmented Large Language Models (LLMs), which incorporate the non-parametric knowledge from external knowledge bases into LLMs, have emerged as a promising approach to enhancing response accuracy in several tasks, such as…
We introduce causal inference reasoning to cross-over trials, with a focus on Thorough QT (TQT) studies. For such trials, we propose different sets of assumptions and consider their impact on the modelling strategy and estimation procedure.…
Quantum machine learning, as an extension of classical machine learning that harnesses quantum mechanics, facilitates effiient learning from data encoded in quantum states. Training a quantum neural network typically demands a substantial…
Agent-based modeling (ABM) offers powerful insights into complex systems, but its practical utility has been limited by computational constraints and simplistic agent behaviors, especially when simulating large populations. Recent…
Explainability of neural network prediction is essential to understand feature importance and gain interpretable insight into neural network performance. However, explanations of neural network outcomes are mostly limited to visualization,…
Recent studies have shown that Large Language Models (LLMs) augmented with chain-of-thought (CoT) reasoning demonstrate impressive problem-solving abilities. However, in this work, we identify a recurring issue where these models…
Genetic association studies, in particular the genome-wide association study design, have provided a wealth of novel insights into the aetiology of a wide range of human diseases and traits. The next challenge consists of understanding the…
This study designs an adaptive experiment for efficiently estimating average treatment effects (ATEs). In each round of our adaptive experiment, an experimenter sequentially samples an experimental unit, assigns a treatment, and observes…
The maximum ${\log}_q$ likelihood estimation method is a generalization of the known maximum $\log$ likelihood method to overcome the problem for modeling non-identical observations (inliers and outliers). The parameter $q$ is a tuning…
Click-through rate (CTR) prediction plays an important role in online advertising systems. On the one hand, traditional CTR prediction models capture the collaborative signals in tabular data via feature interaction modeling, but they lose…
Existing weighting methods for treatment effect estimation are often built upon the idea of propensity scores or covariate balance. They usually impose strong assumptions on treatment assignment or outcome model to obtain unbiased…
There is growing interest in using machine learning (ML) to support clinical diagnosis, but most approaches rely on static, fully observed datasets and fail to reflect the sequential, resource-aware reasoning clinicians use in practice.…
Generalized Linear Mixed Models (GLMMs) are widely used for analysing clustered data. One well-established method of overcoming the integral in the marginal likelihood function for GLMMs is penalized quasi-likelihood (PQL) estimation,…
Semi-supervised action recognition aims to improve spatio-temporal reasoning ability with a few labeled data in conjunction with a large amount of unlabeled data. Albeit recent advancements, existing powerful methods are still prone to…
We introduce Agentic Economic Modeling (AEM), a framework that aligns synthetic LLM choices with small-sample human evidence for reliable econometric inference. AEM first generates task-conditioned synthetic choices via LLMs, then learns a…
Behavioral model diagrams, e.g., sequence diagrams, are an essential form of documentation that are typically designed by system engineers from requirements documentation, either fully manually or assisted by design tools. With the growing…
Spatial transcriptomics (ST) is a novel technology that enables the observation of gene expression at the resolution of individual spots within pathological tissues. ST quantifies the expression of tens of thousands of genes in a tissue…
To gain deeper insights into a complex sensor system through the lens of causality, we present common and individual causal mechanism estimation (CICME), a novel three-step approach to inferring causal mechanisms from heterogeneous data…