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Nonlinear tracking control enabling a dynamical system to track a desired trajectory is fundamental to robotics, serving a wide range of civil and defense applications. In control engineering, designing tracking control requires complete…

Robotics · Computer Science 2023-09-21 Zheng-Meng Zhai , Mohammadamin Moradi , Ling-Wei Kong , Bryan Glaz , Mulugeta Haile , Ying-Cheng Lai

As generative models become ubiquitous, there is a critical need for fine-grained control over the generation process. Yet, while controlled generation methods from prompting to fine-tuning proliferate, a fundamental question remains…

Artificial Intelligence · Computer Science 2026-01-12 Emily Cheng , Carmen Amo Alonso , Federico Danieli , Arno Blaas , Luca Zappella , Pau Rodriguez , Xavier Suau

Gene regulatory networks (GRNs) play a central role in cellular decision-making. Understanding their structure and how it impacts their dynamics constitutes thus a fundamental biological question. GRNs are frequently modeled as Boolean…

Molecular Networks · Quantitative Biology 2024-01-19 Claus Kadelka , Taras-Michael Butrie , Evan Hilton , Jack Kinseth , Addison Schmidt , Haris Serdarevic

Control is essential to the functioning of any neural system. Indeed, under healthy conditions the brain must be able to continuously maintain a tight functional control between the system's inputs and outputs. One may therefore hypothesise…

Neurons and Cognition · Quantitative Biology 2018-05-29 Emma K. Towlson , Petra E. Vertes , Gang Yan , Yee Lian Chew , Denise S. Walker , William R. Schafer , Albert-Laszlo Barabasi

Regulatory networks describe the interactions between molecular or cellular regulators, like transcription factors and genes in gene regulatory networks, kinases and their receptors in signalling networks, or neurons in neural networks. A…

Molecular Networks · Quantitative Biology 2022-12-29 Niklas Bonacker , Johannes Berg

We introduce Network Automata, a framework which couples the topological evolution of a network to its structure. It is useful for dealing with networks in which the topology evolves according to some specified microscopic rules and,…

Physics and Society · Physics 2011-07-12 David M. D. Smith , Jukka-Pekka Onnela , Chiu Fan Lee , Mark Fricker , Neil F. Johnson

Activity in neocortex exhibits a range of behaviors, from irregular to temporally precise, and from weakly to strongly correlated. So far there has been no single theoretical framework that could explain all these behaviors, leaving open…

Neurons and Cognition · Quantitative Biology 2015-11-03 Alexander Lerchner , Peter E. Latham

A large number of complex systems, naturally emerging in various domains, are well described by directed networks, resulting in numerous interesting features that are absent from their undirected counterparts. Among these properties is a…

Physics and Society · Physics 2021-05-19 Joseph D. O'Brien , Kleber A. Oliveira , James P. Gleeson , Malbor Asllani

How biological networks achieve robust control despite relying on imperfect, local information remains an important open question. Here, we identify thermodynamic constraints that can curtail non-equilibrium steady-state responses so…

Statistical Mechanics · Physics 2026-05-27 Carlos Floyd , Aaron R. Dinner , Suriyanarayanan Vaikuntanathan

Nested structure, which is non-random, controls cooperation dynamics and biodiversity in plant-animal mutualistic networks. This structural pattern has been explained in a static (non-growth) network models. However, evolutionary processes…

Populations and Evolution · Quantitative Biology 2015-03-19 Kazuhiro Takemoto , Masanori Arita

We propose a learning-based robust predictive control algorithm that compensates for significant uncertainty in the dynamics for a class of discrete-time systems that are nominally linear with an additive nonlinear component. Such systems…

Systems and Control · Electrical Eng. & Systems 2021-10-15 Rohan Sinha , James Harrison , Spencer M. Richards , Marco Pavone

The topology of a network directly influences the behaviour and controllability of dynamical processes on that network. Therefore, the design of network topologies is an important area of research when examining the control of distributed…

Optimization and Control · Mathematics 2016-09-29 Mathias Hudoba de Badyn , Mehran Mesbahi

Oscillations lie at the core of many biological processes, from the cell cycle, to circadian oscillations and developmental processes. Time-keeping mechanisms are essential to enable organisms to adapt to varying conditions in environmental…

Machine Learning · Statistics 2015-04-27 D Trejo , AJ Millar , G Sanguinetti

We consider a network of identical, first-order linear systems, and investigate how replacing a subset of the systems composing the network with higher-order ones, either taken to be generic or specifically designed, may affect its…

Optimization and Control · Mathematics 2025-04-25 Marco Peruzzo , Giacomo Baggio , Francesco Ticozzi

Deciphering the control principles of metabolism and its interaction with other cellular functions is central to biomedicine and biotechnology. Yet, understanding the efficient control of metabolic fluxes remains elusive for large-scale…

Molecular Networks · Quantitative Biology 2015-09-04 Georg Basler , Zoran Nikoloski , Abdelhalim Larhlimi , Albert-László Barabási , Yang-Yu Liu

The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes. Established approaches rely mostly on deviations of a given network from certain…

Neurons and Cognition · Quantitative Biology 2014-09-19 Marc-Thorsten Huett , Marcus Kaiser , Claus C. Hilgetag

Dynamical systems see widespread use in natural sciences like physics, biology, chemistry, as well as engineering disciplines such as circuit analysis, computational fluid dynamics, and control. For simple systems, the differential…

Complex networks describe a wide range of systems in nature and society, much quoted examples including the cell, a network of chemicals linked by chemical reactions, or the Internet, a network of routers and computers connected by physical…

Statistical Mechanics · Physics 2016-08-31 Reka Albert , Albert-Laszlo Barabasi

In this paper we propose a novel control approach for opinion dynamics on evolving networks. The controls modify the strength of connections in the network, rather than influencing opinions directly, with the overall goal of steering the…

Physics and Society · Physics 2024-04-16 Andrew Nugent , Susana N. Gomes , Marie-Therese Wolfram

Genetic regulatory networks with adaptive responses are widely studied in biology. Usually, models consisting only of a few nodes have been considered. They present one input receptor for activation and one output node where the adaptive…

Molecular Networks · Quantitative Biology 2016-07-20 Pablo Kaluza , Masayo Inoue