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We derive a new 3D model for magnetic particle imaging (MPI) that is able to incorporate realistic magnetic fields in the reconstruction process. In real MPI scanners, the generated magnetic fields have distortions that lead to deformed…

Numerical Analysis · Mathematics 2020-12-30 Gaël Bringout , Wolfgang Erb , Jürgen Frikel

The image reconstruction problem of the tomographic imaging technique magnetic particle imaging (MPI) requires the solution of a linear inverse problem. One prerequisite for this task is that the imaging operator that describes the mapping…

Computational Physics · Physics 2019-07-12 Tobias Kluth , Patryk Szwargulski , Tobias Knopp

Magnetic Particle Imaging (MPI) is a promising noninvasive in vivo imaging modality that makes it possible to map the spatial distribution of superparamagnetic nanoparticles by exposing them to dynamic magnetic fields. In the Field-Free…

Numerical Analysis · Mathematics 2025-08-08 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Magnetic particle imaging (MPI) is a medical imaging modality of recent origin, and it exploits the nonlinear magnetization phenomenon to recover the spatially dependent concentration of the nanoparticles. Currently, image reconstruction in…

Numerical Analysis · Mathematics 2019-04-23 Tobias Kluth , Bangti Jin

Various imaging modalities allow for time-dependent image reconstructions from measurements where its acquisition also has a time-dependent nature. Magnetic particle imaging (MPI) falls into this class of imaging modalities and it thus also…

Numerical Analysis · Mathematics 2023-06-21 Christina Brandt , Tobias Kluth , Tobias Knopp , Lena Westen

Conventional Magnetic Resonance Imaging (MRI) is hampered by long scan times and only qualitative image contrasts that prohibit a direct comparison between different systems. To address these limitations, model-based reconstructions…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Xiaoqing Wang , Zhengguo Tan , Nick Scholand , Volkert Roeloffs , Martin Uecker

Magnetic particle imaging (MPI) is an imaging modality exploiting the nonlinear magnetization behavior of (super-)paramagnetic nanoparticles to obtain a space- and often also time-dependent concentration of a tracer consisting of these…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Sören Dittmer , Tobias Kluth , Mads Thorstein Roar Henriksen , Peter Maass

Magnetic particle imaging (MPI) is a relatively new imaging modality. The nonlinear magnetization behavior of nanoparticles in an applied magnetic field is employed to reconstruct an image of the concentration of nanoparticles. Finding a…

Applied Physics · Physics 2018-07-04 Tobias Kluth

Magnetic particle imaging (MPI) is an emerging medical imaging modality which offers a unique combination of high temporal and spatial resolution, sensitivity and biocompatibility. For system-matrix (SM) based image reconstruction in MPI, a…

Software Engineering · Computer Science 2024-01-12 Anselm von Gladiss , Amir Shayan Ahmadian , Jan Jürjens

Magnetic Resonance Imaging (MRI) is a powerful imaging technique widely used for visualizing structures within the human body and in other fields such as plant sciences. However, there is a demand to develop fast 3D-MRI reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Arya Bangun , Zhuo Cao , Alessio Quercia , Hanno Scharr , Elisabeth Pfaehler

Magnetic particle imaging (MPI) is a promising new in-vivo medical imaging modality in which distributions of super-paramagnetic nanoparticles are tracked based on their response in an applied magnetic field. In this paper we provide a…

Magnetic Particle Imaging (MPI) is a promising tomographic technique for visualizing the spatio-temporal distribution of superparamagnetic nanoparticles, with applications ranging from cancer detection to real-time cardiovascular…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Deep learning-based 3-dimensional (3D) shape reconstruction from 2-dimensional (2D) magnetic resonance imaging (MRI) has become increasingly important in medical disease diagnosis, treatment planning, and computational modeling. This review…

Machine Learning · Computer Science 2025-10-03 Emma McMillian , Abhirup Banerjee , Alfonso Bueno-Orovio

Magnetic Particle Imaging (MPI) is a recent imaging modality where superparamagnetic nanoparticles are employed as tracers. The reconstruction task is to obtain the spatial particle distribution from a voltage signal induced by the…

Numerical Analysis · Mathematics 2025-08-11 Thomas März , Vladyslav Gapyak , Andreas Weinmann

Magnetic particle imaging (MPI) offers unparalleled contrast and resolution for tracing magnetic nanoparticles. A common imaging procedure calibrates a system matrix (SM) that is used to reconstruct data from subsequent scans. The ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Alper Güngör , Baris Askin , Damla Alptekin Soydan , Can Barış Top , Emine Ulku Saritas , Tolga Çukur

Magnetic resonance imaging (MRI) reconstruction is a fundamental task aimed at recovering high-quality images from undersampled or low-quality MRI data. This process enhances diagnostic accuracy and optimizes clinical applications. In…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Xiaoyan Kui , Zijie Fan , Zexin Ji , Qinsong Li , Chengtao Liu , Weixin Si , Beiji Zou

Magnetic particle imaging (MPI) data is commonly reconstructed using a system matrix acquired in a time-consuming calibration measurement. The calibration approach has the important advantage over model-based reconstruction that it takes…

Image and Video Processing · Electrical Eng. & Systems 2019-05-09 Ivo Matteo Baltruschat , Patryk Szwargulski , Florian Griese , Mirco Grosser , René Werner , Tobias Knopp

Magnetic particle imaging (MPI) is an imaging method that can visualize magnetic nanoparticles in positive contrast, without radiation exposure. Recently, we proposed an image reconstruction method for projection-based MPI (pMPI), in which…

Medical Physics · Physics 2023-05-01 Kenya Murase

Magnetic particle imaging (MPI) is a tracer-based imaging modality that detects superparamagnetic iron oxide nanoparticles in vivo, with applications in cancer cell tracking, lymph node mapping, and cell therapy monitoring. We introduce a…

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

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