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Related papers: Modeling delayed processes in biological systems

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Stochastic differential equations (SDEs) provide a natural framework for modelling intrinsic stochasticity inherent in many continuous-time physical processes. When such processes are observed in multiple individuals or experimental units,…

Computation · Statistics 2016-05-19 Gavin A. Whitaker , Andrew Golightly , Richard J. Boys , Chris Sherlock

Learning how complex dynamical systems evolve over time is a key challenge in system identification. For safety critical systems, it is often crucial that the learned model is guaranteed to converge to some equilibrium point. To this end,…

Machine Learning · Computer Science 2021-12-13 Andreas Schlaginhaufen , Philippe Wenk , Andreas Krause , Florian Dörfler

Delay is an inherent feature of genetic regulatory networks. It represents the time required for the assembly of functional regulator proteins. The protein production process is complex, as it includes transcription, translocation,…

Subcellular Processes · Quantitative Biology 2025-12-29 Sean Campbell , Courtney C. White , Amanda M. Alexander , William Ott

Delayed processes are ubiquitous throughout biology. These delays may arise through maturation processes or as the result of complex multi-step networks, and mathematical models with distributed delays are increasingly used to capture the…

Populations and Evolution · Quantitative Biology 2024-10-15 Tyler Cassidy

We study delay-induced transitions in consensus dynamics on signed networks with a ring topology. The proposed model is formulated as a system of delay differential equations incorporating both cooperative and antagonistic interactions, as…

Dynamical Systems · Mathematics 2026-04-20 Hui Wu

Stochastic processes with temporal delay play an important role in science and engineering whenever finite speeds of signal transmission and processing occur. However, an exact mathematical analysis of their dynamics and thermodynamics is…

Statistical Mechanics · Physics 2022-03-02 Viktor Holubec , Artem Ryabov , Sarah A. M. Loos , Klaus Kroy

A common task when analysing dynamical systems is the determination of normal forms near local bifurcations of equilibria. As most of these normal forms have been classified and analysed, finding which particular class of normal form one…

Dynamical Systems · Mathematics 2017-12-14 Jan Sieber

Neural Ordinary Differential Equations (NODEs), a framework of continuous-depth neural networks, have been widely applied, showing exceptional efficacy in coping with representative datasets. Recently, an augmented framework has been…

Machine Learning · Computer Science 2023-04-12 Qunxi Zhu , Yao Guo , Wei Lin

End-to-end learning of dynamical systems with black-box models, such as neural ordinary differential equations (ODEs), provides a flexible framework for learning dynamics from data without prescribing a mathematical model for the dynamics.…

Machine Learning · Statistics 2022-06-20 Paidamoyo Chapfuwa , Sherri Rose , Lawrence Carin , Edward Meeds , Ricardo Henao

We study stochastic delay differential equations (SDDE) where the coefficients depend on the moving averages of the state process. As a first contribution, we provide sufficient conditions under which a linear path functional of the…

Probability · Mathematics 2013-10-17 Salvatore Federico , Peter Tankov

Analysis of mathematical models in ecology and epidemiology often focuses on asymptotic dynamics, such as stable equilibria and periodic orbits. However, many systems exhibit long transient behaviors where certain aspects of the dynamics…

Dynamical Systems · Mathematics 2025-11-06 Anthony Pasion , Felicia Magpantay

Dynamical systems driven by nonlinear delay SDEs with small noise can exhibit important rare events on long timescales. When there is no delay, classical large deviations theory quantifies rare events such as escapes from metastable fixed…

Probability · Mathematics 2018-01-04 Robert Azencott , Brett Geiger , William Ott

Neural Ordinary Differential Equations (NODEs), a framework of continuous-depth neural networks, have been widely applied, showing exceptional efficacy in coping with some representative datasets. Recently, an augmented framework has been…

Machine Learning · Computer Science 2021-02-23 Qunxi Zhu , Yao Guo , Wei Lin

The celebrated Mackey-Glass model describes the dynamics of physiological \textit{delayed} systems in which the actual evolution depends on the values of the variables at some \textit{previous} times. This kind of systems are usually…

Chaotic Dynamics · Physics 2014-08-22 Pablo Amil , Cecilia Cabeza , Arturo C. Martí

We consider stochastic dynamical systems defined by differential equations with a uniform random time delay. The latter equations are shown to be equivalent to deterministic higher-order differential equations: for an $n$-th order equation…

Statistical Mechanics · Physics 2011-10-11 P. L. Krapivsky , J. M. Luck , K. Mallick

Delay differential equations are used as a model when the effect of past states has to be taken into account. In this work we consider delay models of chemical reaction networks with mass action kinetics. We obtain a sufficient condition…

Dynamical Systems · Mathematics 2020-06-05 Gheorghe Craciun , Maya Mincheva , Casian Pantea , Polly Y. Yu

1. Understanding the mechanisms underlying biological systems, and ultimately, predicting their behaviours in a changing environment requires overcoming the gap between mathematical models and experimental or observational data.…

Quantitative Methods · Quantitative Biology 2017-04-19 Philipp H Boersch-Supan , Sadie J Ryan , Leah R Johnson

Stochastic differential equations (SDEs) are established tools to model physical phenomena whose dynamics are affected by random noise. By estimating parameters of an SDE intrinsic randomness of a system around its drift can be identified…

Computation · Statistics 2012-05-03 Umberto Picchini , Susanne Ditlevsen

Time delay estimation plays a critical role in control, stabilization and state estimation of many practical system with time delay. In this paper, we propose a method to estimate delay for discrete time linear multiple-input…

Systems and Control · Electrical Eng. & Systems 2021-09-08 Iman Shafikhani , Hazhar Sufi Karimi , Mohammad Mohammadian , Amin Ramezani , Hamid Reza Momeni

Systems of differential equations with state-dependent delay are considered. The delay dynamically depends on the state i.e. is governed by an additional differential equation. By applying the time transformations we arrive to constant…

Classical Analysis and ODEs · Mathematics 2017-06-29 A. V. Rezounenko