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Engineering simple, artificial models of living cells allows synthetic biologists to study cellular functions under well-controlled conditions. Reconstituting multicellular behaviors with synthetic cell-mimics is still a challenge because…

Biomolecules · Quantitative Biology 2021-04-29 Imre Banlaki , Francois-Xavier Lehr , Henrike Niederholtmeyer

Quantum computing offers the promise of speedups for scientific computations, but its application to reacting flows is hindered by nonlinear source terms, the challenges of time-dependent simulations, and the difficulty of extracting…

Quantum Physics · Physics 2026-03-17 Jizhi Zhang , Ziang Yang , Zhaoyuan Meng , Zhen Lu , Yue Yang

Precise characterization of three-dimensional heterogeneous media is indispensable in finding the relationships between structure and macroscopic physical properties (permeability, conductivity, and others). The most widely used…

Materials Science · Physics 2021-09-15 Aleksei Cherkasov , Andrey Ananev , Marina Karsanina , Aleksey Khlyupin , Kirill Gerke

Experimental studies of protein-pattern formation have stimulated new interest in the dynamics of reaction-diffusion systems. However, a comprehensive theoretical understanding of the dynamics of such highly nonlinear, spatially extended…

Pattern Formation and Solitons · Physics 2020-11-24 Fridtjof Brauns , Jacob Halatek , Erwin Frey

Under extreme operating conditions, characterized by high particle multiplicity and heavily overlapping shower energy deposits, classical particle flow algorithms encounter pronounced limitations in resolution, efficiency, and accuracy. To…

Instrumentation and Detectors · Physics 2025-05-13 Yu Wang , Yangguang Zhang , Shengxiang Lin , Xingyi Zhang , Han Zhang

We present flow matching for reaction coordinates (FMRC), a novel deep learning algorithm designed to identify optimal reaction coordinates (RC) in biomolecular reversible dynamics. FMRC is based on the mathematical principles of…

Machine Learning · Computer Science 2024-12-25 Mingyuan Zhang , Zhicheng Zhang , Hao Wu , Yong Wang

Turbulent flows driven by a vertically invariant body force were proven to become exactly two-dimensional above a critical rotation rate, using upper bound theory. This transition in dimensionality of a turbulent flow has key consequences…

Fluid Dynamics · Physics 2023-07-19 Kannabiran Seshasayanan , Basile Gallet

We develop a continuous mathematical model of population dynamics that describes the sequential emergence of new genotypes under limited resources. The framework models genotype density as a nonlinear flow in mutation space, combining…

Populations and Evolution · Quantitative Biology 2025-12-10 Alexander Bratus , Tatiana Yakushkina , Vladimir Posvyanski

Characterizing complex many-body phases of matter has been a central question in quantum physics for decades. Numerical methods built around approximations of the renormalization group (RG) flow equations have offered reliable and…

Strongly Correlated Electrons · Physics 2024-03-25 Jiawei Zang , Matija Medvidović , Dominik Kiese , Domenico Di Sante , Anirvan M. Sengupta , Andrew J. Millis

A new three-dimensional (3D) multiphase computational fluid dynamics (CFD) model for adsorption physics in packed beds of spherical beads is developed and validated. The model is constituted at a macroscopic scale that integrates new…

Fluid Dynamics · Physics 2026-03-24 Mohamad Najib Nadamani , Mostafa Safdari Shadloo , Talib Dbouk

Active gel theory has recently been very successful in describing biologically active materials such as actin filaments or moving bacteria in temporally fixed and simple geometries such as cubes or spheres. Here we develop a computational…

Biological Physics · Physics 2019-07-10 Christian Bächer , Stephan Gekle

Deep generative models and neural operators have demonstrated significant potential for 3D aerodynamic inference. However, they often face inherent challenges in maintaining physical consistency and preserving high-frequency features,…

Numerical Analysis · Mathematics 2026-04-28 Ruiling Jiang , Yong Zhang , Houbiao Li

Generating synthetic CT (sCT) from MRI or CBCT plays a crucial role in enabling MRI-only and CBCT-based adaptive radiotherapy, improving treatment precision while reducing patient radiation exposure. To address this task, we adopt a fully…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Arnela Hadzic , Simon Johannes Joham , Martin Urschler

Reconstructing and tracking dynamic 3D scenes remains a fundamental challenge in computer vision. Existing approaches often decouple geometry from motion: multi-view reconstruction methods assume static scenes, while dynamic tracking…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Shenhan Qian , Ganlin Zhang , Shangzhe Wu , Daniel Cremers

Normalizing flows are an essential alternative to GANs for generative modelling, which can be optimized directly on the maximum likelihood of the dataset. They also allow computation of the exact latent vector corresponding to an image…

Machine Learning · Computer Science 2021-08-10 Sandeep Nagar , Marius Dufraisse , Girish Varma

As protein folding is a NP-complete problem, artificial intelligence tools like neural networks and genetic algorithms are used to attempt to predict the 3D shape of an amino acids sequence. Underlying these attempts, it is supposed that…

Biomolecules · Quantitative Biology 2015-11-03 Jacques M. Bahi , Nathalie M. -L. Cote , Christophe Guyeux

Understanding the three-dimensional (3D) structure and stability of DNA is fundamental for its biological function and the design of novel drugs. In this study, we introduce an improved coarse-grained (CG) model, incorporating a more…

Soft Condensed Matter · Physics 2025-01-22 Xunxun Wang , Ya-Zhou Shi

We investigate diffusion-limited reactions between a diffusing particle and a target site on a semiflexible polymer, a key factor determining the kinetics of DNA-protein binding and polymerization of cytoskeletal filaments. Our theory…

Soft Condensed Matter · Physics 2010-12-08 Yann von Hansen , Roland R. Netz , Michael Hinczewski

Concentrated solutions of short blunt-ended DNA duplexes, down to 6 base pairs, are known to order into the nematic liquid crystal phase. This self-assembly is due to the stacking interactions between the duplex terminals that promotes…

Soft Condensed Matter · Physics 2015-05-30 Cristiano De Michele , Tommaso Bellini , Francesco Sciortino

The aim of our work is to study the effect of geometry variation on nucleation times and to address its role in the context of eukaryotic chemotaxis (i.e. the process which allows cells to identify and follow a gradient of chemical…

Statistical Mechanics · Physics 2010-02-10 Carla Bosia , Michele Caselle , Davide Corá