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We study the emergence of the collective spatio-temporal macroscopic properties of the immune system, by representing individually the elementary interactions between its microscopic components (antibodies, antigens, cytokines). The results…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Yoram Louzoun , Sorin Solomon , Henri Atlan , Irun. R. Cohen

A two-body interaction or force between quantum particles is ubiquitous in nature, and the microscopic description in terms of the bare two-body interaction is the basis for quantitatively describing interacting few- and many-body systems.…

Quantum Gases · Physics 2025-06-17 Kantaro Honda , Yosuke Takasu , Yuki Haruna , Yusuke Nishida , Yoshiro Takahashi

Allosteric interactions occur when binding at one part of a complex affects the interactions at another part. Allostery offers a high degree of control in multi-species processes, and these interactions play a crucial role in many…

Soft Condensed Matter · Physics 2025-07-14 Jakob Metson

Small thermodynamic systems exhibit peculiar behavior different from that observed in long-scale systems. Non-equilibrium processes taking place in those systems are strongly influenced by the presence of fluctuations which can be large.…

Statistical Mechanics · Physics 2007-05-23 J. M. Rubi

Transition State Theory overestimates reaction rates in solution because conventional dividing surfaces between reagents and products are crossed many times by the same reactive trajectory. We describe a recipe for constructing a…

Statistical Mechanics · Physics 2007-05-23 Thomas Bartsch , Rigoberto Hernandez , T. Uzer

In natural settings, intermittent dynamics are ubiquitous and often arise from a coupling between external driving and spatial heterogeneities. A well-known example is the generation of transient, turbulent puffs of fluid through a pipe…

Adaptation and Self-Organizing Systems · Physics 2020-07-01 Guram Gogia , Wentao Yu , Justin C. Burton

Even though the evolution of an isolated quantum system is unitary, the complexity of interacting many-body systems prevents the observation of recurrences of quantum states for all but the smallest systems. For large systems one can not…

State transitions are fundamental in biological systems but challenging to observe directly. Here, we present the first single-cell observation of state transitions in a synthetic bacterial genetic circuit. Using a mother machine, we…

Statistical Mechanics · Physics 2026-05-21 Jianzhe Wei , Jingwen Zhu , Pan Chu , Liang Luo , Xiongfei Fu

A one-dimensional model on a line of the length L is investigated, which involves particle diffusion as well as single particle annihilation. There are also creation and annihilation at the boundaries. The static and dynamical behaviors of…

Mathematical Physics · Physics 2014-03-17 Mohammad Khorrami , Amir Aghamohammadi

The number of molecules involved in a cell or subcellular structure is sometimes rather small. In this situation, ordinary macroscopic-level fluctuations can be overwhelmed by non-negligible large fluctuations, which results in drastic…

Molecular Networks · Quantitative Biology 2016-11-15 Nen Saito , Yuki Sughiyama , Kunihiko Kaneko

I show how transition systems can be applied to the naturally concurrent behaviour of excitable media. I consider structured excitable media, in which excitations are constrained to propagate only in defined narrow channels, and cannot…

Pattern Formation and Solitons · Physics 2012-11-27 William M. Stevens

The Minority Game framework was recently generalized to account for the possibility that agents adapt not only through strategy selection but also by diversifying their response according to the kind of dynamical regime, or the risk, they…

Disordered Systems and Neural Networks · Physics 2009-11-11 A. Tedeschi , A. De Martino , I. Giardina

Distribution-dependent stochastic dynamical systems arise widely in engineering and science. We consider a class of such systems which model the limit behaviors of interacting particles moving in a vector field with random fluctuations. We…

Numerical Analysis · Mathematics 2023-09-15 Wei Wei , Jianyu Hu

Molecular dynamics simulations are performed for a supercooled simple liquid with changing the system size from N=108 to $10^4$ to examine possible finite-size effects. Although almost no systematic deviation is detected in the static pair…

Soft Condensed Matter · Physics 2007-05-23 Kang Kim , Ryoichi Yamamoto

Stochastic models of chemical reaction networks are an important tool to describe and analyze noise effects in cell biology. When chemical species and reaction rates in a reaction system have different orders of magnitude, the associated…

Probability · Mathematics 2020-09-15 German Enciso , Jinsu Kim

Turing's mechanism is often invoked to explain periodic patterns in nature, although direct experimental support is scarce. Turing patterns form in reaction-diffusion systems when the activating species diffuse much slower than the…

Biological Physics · Physics 2024-03-15 Lucas Menou , Chengjie Luo , David Zwicker

In this paper, we study the phase transition behavior emerging from the interactions among multiple agents in the presence of noise. We propose a simple discrete-time model in which a group of non-mobile agents form either a fixed connected…

Optimization and Control · Mathematics 2008-10-21 Jialing Liu , Vikas Yadav , Hullas Sehgal , Joshua M. Olson , Haifeng Liu , Nicola Elia

The decoupling of spin and density dynamics is a remarkable feature of quantum one-dimensional many-body systems. In a few-body regime, however, little is known about this phenomenon. To address this problem, we study the time evolution of…

Quantum Gases · Physics 2020-01-13 Rafael Emilio Barfknecht , Angela Foerster , Nikolaj Thomas Zinner

In molecular simulations, one of the most difficult points is to track the real dynamics of many-body systems from the first principle. The present study shows that step-size dependences have an unexpected effect on simulation results, even…

chao-dyn · Physics 2008-02-03 Ken Umeno

The exact equations of motion for microscopic density of classical many-body system with account of inter-particle retarded interactions are derived. It is shown that interactions retardation leads to irreversible behaviour of many-body…

Statistical Mechanics · Physics 2015-09-22 A. Yu. Zakharov , M. A. Zakharov