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One of the most important problems of data processing in high energy and nuclear physics is the event reconstruction. Its main part is the track reconstruction procedure which consists in looking for all tracks that elementary particles…

Machine Learning · Computer Science 2019-10-02 Dmitriy Baranov , Sergey Mitsyn , Pavel Goncharov , Gennady Ososkov

Single-beam scanning electron microscopes (SEM) are widely used to acquire massive data sets for biomedical study, material analysis, and fabrication inspection. Datasets are typically acquired with uniform acquisition: applying the…

Image and Video Processing · Electrical Eng. & Systems 2021-01-11 Lu Mi , Hao Wang , Yaron Meirovitch , Richard Schalek , Srinivas C. Turaga , Jeff W. Lichtman , Aravinthan D. T. Samuel , Nir Shavit

Deep learning model trained by imbalanced data may not work satisfactorily since it could be determined by major classes and thus may ignore the classes with small amount of data. In this paper, we apply deep learning based imbalanced data…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Ziqian Luo , Xiangrui Zeng , Zhipeng Bao , Min Xu

Cryo-electron microscopy is a revolutionary technique that can provide 3D density maps at near-atomic resolution. However, map validation is still an open issue in the field. Despite several efforts from the community, it is possible to…

Biological Physics · Physics 2019-08-06 Sebastian Ortiz , Luka Stanisic , Boris A Rodriguez , Markus Rampp , Gerhard Hummer , Pilar Cossio

Knowledge of a protein's atomic conformational ensemble is critical to determining its function, yet state-of-the-art ensemble prediction models are limited by lack of high-quality conformational data from simulation or experiment. Recent…

Machine Learning · Computer Science 2026-05-12 Jay Shenoy , Miro Astore , Axel Levy , Frédéric Poitevin , Sonya M. Hanson , Gordon Wetzstein

Three-dimensional electron diffraction (3D ED) has emerged as a powerful method for solving the structures of sub-micron-sized particles down to nanoparticles. However, it faces technical challenges when applied to beam-sensitive samples or…

Seismic phase picking and magnitude estimation are essential components of real time earthquake monitoring and earthquake early warning systems. Reliable phase picking enables the timely detection of seismic wave arrivals, facilitating…

Purpose: To develop and evaluate a deep learning-based method that allows to perform myocardial infarct segmentation in a fully-automated way. Materials and Methods: For this retrospective study, a cascaded framework of two and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Matthias Schwab , Mathias Pamminger , Christian Kremser , Markus Haltmeier , Agnes Mayr

Pruning is a widely used method for compressing Deep Neural Networks (DNNs), where less relevant parameters are removed from a DNN model to reduce its size. However, removing parameters reduces model accuracy, so pruning is typically…

Machine Learning · Computer Science 2025-06-17 Wenhao Hu , Paul Henderson , José Cano

Cosmic-ray acceleration processes in astrophysical plasmas are often investigated with fully-kinetic or hybrid kinetic numerical simulations, which enable us to describe a detailed microphysics of particle energization mechanisms. Tracing…

High Energy Astrophysical Phenomena · Physics 2025-02-12 Gabriel Torralba Paz , Artem Bohdan , Jacek Niemiec

In this work we present a system based on a Deep Learning approach, by using a Convolutional Neural Network, capable of classifying protein chains of amino acids based on the protein description contained in the Protein Data Bank. Each…

Machine Learning · Computer Science 2021-11-04 Damiano Perri , Marco Simonetti , Andrea Lombardi , Noelia Faginas-Lago , Osvaldo Gervasi

Endoscopic depth estimation is a critical technology for improving the safety and precision of minimally invasive surgery. It has attracted considerable attention from researchers in medical imaging, computer vision, and robotics. Over the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ke Niu , Zeyun Liu , Xue Feng , Heng Li , Qika Lin , Kaize Shi

Electron microscopy is widely used to explore defects in crystal structures, but human detecting of defects is often time-consuming, error-prone, and unreliable, and is not scalable to large numbers of images or real-time analysis. In this…

Advances on cryo-electron imaging technologies have led to a rapidly increasing number of density maps. Alignment and comparison of density maps play a crucial role in interpreting structural information, such as conformational…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Bintao He , Fa Zhang , Chenjie Feng , Jianyi Yang , Xin Gao , Renmin Han

In many optical metrology techniques, fringe pattern analysis is the central algorithm for recovering the underlying phase distribution from the recorded fringe patterns. Despite extensive research efforts for decades, how to extract the…

Image and Video Processing · Electrical Eng. & Systems 2019-03-22 Shijie Feng , Qian Chen , Guohua Gu , Tianyang Tao , Liang Zhang , Yan Hu , Wei Yin , Chao Zuo

Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

The Cryo-EM 3D particle reconstruction is essential for identifying protein and uncover the biological mechanism of the macro-molecules. In this paper, we use Kam method for reconstruction. Kam method is \textit{ab-initio}, and it assumes…

Quantitative Methods · Quantitative Biology 2019-06-21 Yin Xian

X-ray Ptychography is an advanced computational microscopy technique which is delivering exceptionally detailed quantitative imaging of biological and nanotechnology specimens. However coarse parametrisation in propagation distance,…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Francesco Guzzi , George Kourousias , Fulvio Billè , Roberto Pugliese , Alessandra Gianoncelli , Sergio Carrato

Background Medical and life science research generates millions of publications, and it is a great challenge for researchers to utilize this information in full since its scale and complexity greatly surpasses human reading capabilities.…

Educational Data Mining (EDM) has emerged as a vital field of research, which harnesses the power of computational techniques to analyze educational data. With the increasing complexity and diversity of educational data, Deep Learning…

Machine Learning · Computer Science 2024-06-12 Yuanguo Lin , Hong Chen , Wei Xia , Fan Lin , Zongyue Wang , Yong Liu