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Stochastic reaction-diffusion models have become an important tool in studying how both noise in the chemical reaction process and the spatial movement of molecules influences the behavior of biological systems. There are two primary…

Analysis of PDEs · Mathematics 2013-04-23 Ikemefuna C. Agbanusi , Samuel A. Isaacson

The problem of the time required for a diffusing molecule, within a large bounded domain, to first locate a small target is prevalent in biological modeling. Here we study this problem for a small spherical target. We develop uniform in…

Biological Physics · Physics 2013-08-06 Samuel A. Isaacson , Jay Newby

We consider steady-state diffusion in a bounded planar domain with multiple small targets on a smooth boundary. Using the method of matched asymptotic expansions, we investigate the competition of these targets for a diffusing particle and…

Analysis of PDEs · Mathematics 2025-11-18 Denis S. Grebenkov , Michael J. Ward

The kinetics of bimolecular reactions in solution depends, among other factors, on intermolecular forces such as steric repulsion or electrostatic interaction. Microscopically, a pair of molecules first has to meet by diffusion before the…

Soft Condensed Matter · Physics 2019-10-24 Manuel Dibak , Christoph Fröhner , Frank Noé , Felix Höfling

It has been established that there is an inherent limit to the accuracy of the reaction-diffusion master equation. Specifically, there exists a fundamental lower bound on the mesh size, below which the accuracy deteriorates as the mesh is…

Numerical Analysis · Mathematics 2016-01-27 Stefan Hellander , Linda Petzold

This paper proposes a novel reaction-diffusion system approximation tailored for singular diffusion problems, typified by the fast diffusion equation. While such approximation methods have been successfully applied to degenerate parabolic…

Analysis of PDEs · Mathematics 2026-04-01 Hideki Murakawa , Florian Salin

The long-time behavior of a reaction-diffusion front between one static (e.g. porous solid) reactant A and one initially separated diffusing reactant B is analyzed for the mean-field reaction-rate density R(\rho_A,\rho_B) =…

Chemical Physics · Physics 2009-10-31 Martin Z. Bazant , Howard A. Stone

We present a unified approach to characterising fast-reaction limits of systems of either two reaction-diffusion equations, or one reaction-diffusion equation and one ordinary differential equation, on unbounded domains, motivated by models…

Analysis of PDEs · Mathematics 2016-04-26 E. C. M. Crooks , D. Hilhorst

We consider a single-species diffusion-limited annihilation reaction with reactants confined to a two-dimensional surface with one arbitrarily large dimension and the other comparable in size to interparticle distances. This situation could…

Biomolecules · Quantitative Biology 2015-03-20 Aleksandr Kivenson , Michael F. Hagan

An overview of the author's papers on the new approach to the Brownian coagulation theory and its generalization to the diffusion-limited reaction rate theory is presented. The traditional diffusion approach of the Smoluchowski theory for…

Chemical Physics · Physics 2016-05-24 Mikhail S. Veshchunov

We study diffusion-limited coalescence, A+A<-->A, in one dimension, in the presence of a diffusing trap. The system may be regarded as a generalization of von Smoluchowski's model for reaction rates, in that: (a) it includes reactions…

Statistical Mechanics · Physics 2015-06-25 Aleksandar Donev , Jeff Rockwell , Daniel ben-Avraham

We study a large class of 1D reaction diffusion models with quenched disorder using a real space renormalization group method (RSRG) which yields exact results at large time. Particles (e.g. of several species) undergo diffusion with random…

Condensed Matter · Physics 2009-10-31 Pierre Le Doussal , Cecile Monthus

We consider a reaction-diffusion system where some components react and diffuse on the boundary of a region, while other components diffuse in the interior and react with those on the boundary through mass transport. We establish criteria…

Analysis of PDEs · Mathematics 2015-12-31 Vandana Sharma , Jeff Morgan

Steric or attractive interactions among reactants or between reactants and inert crowders can substantially influence the total rate of a diffusion-influenced reaction in the liquid phase. However, the role of the product species, that has…

Chemical Physics · Physics 2018-04-19 Rafael Roa , Toni Siegl , Won Kyu Kim , Joachim Dzubiella

A system of interacting Brownian particles subject to short-range repulsive potentials is considered. A continuum description in the form of a nonlinear diffusion equation is derived systematically in the dilute limit using the method of…

Statistical Mechanics · Physics 2017-10-12 Maria Bruna , S. Jonathan Chapman , Martin Robinson

We study long-time properties of reversible reaction-diffusion systems of type A + B <-> C by means of perturbation expansion in powers of 1/t (inverse of time). For the case of equal diffusion coefficients we present exact formulas for the…

Statistical Mechanics · Physics 2009-11-07 Zbigniew Koza

We consider a coupled system of two singularly perturbed reaction-diffusion equations, with two small parameters $0< \epsilon \le \mu \le 1$, each multiplying the highest derivative in the equations. The presence of these parameters causes…

Numerical Analysis · Mathematics 2015-03-19 Jens Markus Melenk , Christos Xenophontos , Lisa Oberbroeckling

We consider a reaction-diffusion system for two densities lying in adjacent domains of $\mathbb{R}^N$. We treat two configurations: either a cylinder and its complement, or two half-spaces. Diffusion and reaction heterogeneities for the two…

Analysis of PDEs · Mathematics 2025-06-06 Henri Berestycki , Luca Rossi , Andrea Tellini

Many cellular and subcellular biological processes can be described in terms of diffusing and chemically reacting species (e.g. enzymes). Such reaction-diffusion processes can be mathematically modelled using either deterministic…

Biological Physics · Physics 2015-06-26 Radek Erban , S. Jonathan Chapman

We show that, for any spatially discretized system of reaction-diffusion, the approximate solution given by the explicit Euler time-discretization scheme converges to the exact time-continuous solution, provided that diffusion coefficient…

Optimization and Control · Mathematics 2019-12-12 Adrien Le Coënt , Laurent Fribourg
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