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The emergence and development of cancer is a consequence of the accumulation over time of genomic mutations involving a specific set of genes, which provides the cancer clones with a functional selective advantage. In this work, we model…

Machine Learning · Computer Science 2017-03-10 Daniele Ramazzotti , Marco S. Nobile , Paolo Cazzaniga , Giancarlo Mauri , Marco Antoniotti

Spiking Neural Networks (SNN) are models for "realistic" neuronal computation, which makes them somehow different in scope from "ordinary" deep-learning models widely used in AI platforms nowadays. SNNs focus on timed latency (and possibly…

Artificial Intelligence · Computer Science 2025-06-17 Zhen Yao , Elisabetta De Maria , Robert De Simone

The projected belief network (PBN) is a layered generative network (LGN) with tractable likelihood function, and is based on a feed-forward neural network (FFNN). There are two versions of the PBN: stochastic and deterministic (D-PBN), and…

Machine Learning · Computer Science 2022-04-28 Paul M Baggenstoss

Incorporating computational fluid dynamics in the design process of jets, spacecraft, or gas turbine engines is often challenged by the required computational resources and simulation time, which depend on the chosen physics-based…

Computational Physics · Physics 2019-12-09 Cristina White , Daniela Ushizima , Charbel Farhat

Stochastic Processing Networks (SPNs) can be used to model communication networks, manufacturing systems, service systems, etc. We consider a real-time SPN where tasks generate jobs with strict deadlines according to their traffic patterns.…

Networking and Internet Architecture · Computer Science 2012-04-23 I-Hong Hou , Rahul Singh

Accurate crowd simulation is crucial for public safety management, emergency evacuation planning, and intelligent transportation systems. However, existing methods, which typically model crowds as a collection of independent individual…

Machine Learning · Computer Science 2026-04-14 Zijin Liu , Xu Geng , Wenshuai Xu , Xiang Zhao , Yan Xia , You Song

Modern safety-critical systems are heterogeneous, complex, and highly dynamic. They require reliability evaluation methods that go beyond the classical static methods such as fault trees, event trees, or reliability block diagrams.…

Logic in Computer Science · Computer Science 2020-04-15 Clemens Dubslaff , Andrey Morozov , Christel Baier , Klaus Janschek

The computational properties of neural systems are often thought to be implemented in terms of their network dynamics. Hence, recovering the system dynamics from experimentally observed neuronal time series, like multiple single-unit (MSU)…

Neurons and Cognition · Quantitative Biology 2017-07-05 Daniel Durstewitz

When using Bayesian networks for modelling the behavior of man-made machinery, it usually happens that a large part of the model is deterministic. For such Bayesian networks deterministic part of the model can be represented as a Boolean…

Artificial Intelligence · Computer Science 2013-01-18 Thomas D. Nielsen , Pierre-Henri Wuillemin , Finn Verner Jensen , Uffe Kjærulff

The utilization of model checking has been suggested as a formal verification technique for analyzing critical systems. However, the primary challenge in applying to complex systems is state space explosion problem. To address this issue,…

Logic in Computer Science · Computer Science 2023-08-08 Mohammadsadegh Mohaghegh , Khayyam Salehi

The customizable nature of deep learning models have allowed them to be successful predictors in various disciplines. These models are often trained with respect to thousands or millions of instances for complicated problems, but the…

Machine Learning · Computer Science 2019-12-24 Drimik Roy Chowdhury , Muhammad Firmansyah Kasim

This paper presents the foundation for a decomposition theory for Boolean networks, a type of discrete dynamical system that has found a wide range of applications in the life sciences, engineering, and physics. Given a Boolean network…

Dynamical Systems · Mathematics 2022-06-10 Claus Kadelka , Reinhard Laubenbacher , David Murrugarra , Alan Veliz-Cuba , Matthew Wheeler

Spiking Neural Networks (SNNs) hold great potential to realize brain-inspired, energy-efficient computational systems. However, current SNNs still fall short in terms of multi-scale temporal processing compared to their biological…

Neural and Evolutionary Computing · Computer Science 2024-08-28 Xinyi Chen , Jibin Wu , Chenxiang Ma , Yinsong Yan , Yujie Wu , Kay Chen Tan

The ability to learn polynomials and generalize out-of-distribution is essential for simulation metamodels in many disciplines of engineering, where the time step updates are described by polynomials. While feed forward neural networks can…

Machine Learning · Computer Science 2023-07-21 Jesper Hauch , Christoffer Riis , Francisco C. Pereira

In this study, a Bayesian Network (BN) is considered to represent a nuclear plant mechanical system degradation. It describes a causal representation of the phenomena involved in the degradation process. Inference from such a BN needs to…

Methodology · Statistics 2009-05-19 Gilles Celeux , Franck Corset , A. Lannoy , Benoit Ricard

This paper proposes a novel methodology for probabilistic dynamic security assessment and enhancement of power systems that considers load and generation variability, N-2 contingencies, and uncertain cascade propagation caused by uncertain…

Systems and Control · Electrical Eng. & Systems 2025-05-05 Frédéric Sabot , Pierre-Etienne Labeau , Pierre Henneaux

Active learning optimizes the exploration of large parameter spaces by strategically selecting which experiments or simulations to conduct, thus reducing resource consumption and potentially accelerating scientific discovery. A key…

Machine Learning · Computer Science 2024-05-20 Maxim Ziatdinov

When expert systems based on causal probabilistic networks (CPNs) reach a certain size and complexity, the "combinatorial explosion monster" tends to be present. We propose an approximation scheme that identifies rarely occurring cases and…

Artificial Intelligence · Computer Science 2013-04-05 Frank Jensen , S. K. Anderson

To date, the simulation of organ deformations for applications like therapy planning or image-guided interventions is calculated by solving the elastodynamics equations. While efficient solvers have been proposed for fast simulations,…

Quantitative Methods · Quantitative Biology 2018-12-18 Felix Meister , Tiziano Passerini , Viorel Mihalef , Ahmet Tuysuzoglu , Andreas Maier , Tommaso Mansi

Simulation speed matters for neuroscientific research: this includes not only how quickly the simulated model time of a large-scale spiking neuronal network progresses, but also how long it takes to instantiate the network model in computer…