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The rapid advancement of high-throughput sequencing and other assay technologies has resulted in the generation of large and complex multi-omics datasets, offering unprecedented opportunities for advancing precision medicine strategies.…

Quantitative Methods · Quantitative Biology 2025-01-30 Ana R. Baião , Zhaoxiang Cai , Rebecca C Poulos , Phillip J. Robinson , Roger R Reddel , Qing Zhong , Susana Vinga , Emanuel Gonçalves

Advances in AI, and especially machine learning, are increasingly drawing research interest and efforts towards predictive process monitoring, the subfield of process mining (PM) that concerns predicting next events, process outcomes and…

Artificial Intelligence · Computer Science 2021-07-06 Hans Weytjens , Jochen De Weerdt

Longitudinal studies are frequently used in medical research and involve collecting repeated measures on individuals over time. Observations from the same individual are invariably correlated and thus an analytic approach that accounts for…

Missing data are a concern in many real world data sets and imputation methods are often needed to estimate the values of missing data, but data sets with excessive missingness and high dimensionality challenge most approaches to…

Machine Learning · Statistics 2021-04-22 Andrew J. Becker , James P. Bagrow

Traditionally, machine learning algorithms rely on the assumption that all features of a given dataset are available for free. However, there are many concerns such as monetary data collection costs, patient discomfort in medical…

Machine Learning · Computer Science 2019-07-02 Mohammad Kachuee , Kimmo Karkkainen , Orpaz Goldstein , Davina Zamanzadeh , Majid Sarrafzadeh

Genomics data such as RNA gene expression, methylation and micro RNA expression are valuable sources of information for various clinical predictive tasks. For example, predicting survival outcomes, cancer histology type and other patients'…

Genomics · Quantitative Biology 2022-05-26 Sophie Peacock , Etai Jacob , Nikolay Burlutskiy

A key task in ML is to optimize models at various stages, e.g. by choosing hyperparameters or picking a stopping point. A traditional ML approach is to use validation loss, i.e. to apply the training loss function on a validation set to…

Machine Learning · Computer Science 2026-01-23 Charles B. Delahunt , Courosh Mehanian , Daniel E. Shea , Matthew P. Horning

From medical charts to national census, healthcare has traditionally operated under a paper-based paradigm. However, the past decade has marked a long and arduous transformation bringing healthcare into the digital age. Ranging from…

Computers and Society · Computer Science 2018-01-29 Keith Feldman , Louis Faust , Xian Wu , Chao Huang , Nitesh V. Chawla

Baseline covariates in randomized experiments are often used in the estimation of treatment effects, for example, when estimating treatment effects within covariate-defined subgroups. In practice, however, covariate values may be missing…

Methodology · Statistics 2023-08-29 Gauri Kamat , Jerome P. Reiter

This paper contributes a set of quality metrics for identification and visual analysis of structured missingness in high-dimensional data. Missing values in data are a frequent challenge in most data generating domains and may cause a range…

Graphics · Computer Science 2025-05-30 Sara Johansson Fernstad , Sarah Alsufyani , Silvia Del Din , Alison Yarnall , Lynn Rochester

We present DeepMVI, a deep learning method for missing value imputation in multidimensional time-series datasets. Missing values are commonplace in decision support platforms that aggregate data over long time stretches from disparate…

Machine Learning · Computer Science 2023-06-22 Parikshit Bansal , Prathamesh Deshpande , Sunita Sarawagi

Missing data is a common issue in many biomedical studies. Under a paired design, some subjects may have missing values in either one or both of the conditions due to loss of follow-up, insufficient biological samples, etc. Such partially…

Question classification is one of the important links in the research of question and answering system. The existing question classification models are more trained on public data sets. At present, there is a lack of question classification…

Computation and Language · Computer Science 2022-02-02 Jinzhang Liu

Missing values in electronic health record (EHR) data pose a significant challenge for epidemiologic research. Traditional methods for handling missing data, like mean imputation, may introduce bias. Multiple imputation (MI) offers a…

The quality of underlying training data is very crucial for building performant machine learning models with wider generalizabilty. However, current machine learning (ML) tools lack streamlined processes for improving the data quality. So,…

Machine Learning · Computer Science 2021-12-16 Atindriyo Sanyal , Vikram Chatterji , Nidhi Vyas , Ben Epstein , Nikita Demir , Anthony Corletti

Fairness in artificial intelligence models has gained significantly more attention in recent years, especially in the area of medicine, as fairness in medical models is critical to people's well-being and lives. High-quality medical…

Computer Vision and Pattern Recognition · Computer Science 2024-05-02 Yu Tian , Min Shi , Yan Luo , Ava Kouhana , Tobias Elze , Mengyu Wang

Supervised training of deep learning models requires large labeled datasets. There is a growing interest in obtaining such datasets for medical image analysis applications. However, the impact of label noise has not received sufficient…

Computer Vision and Pattern Recognition · Computer Science 2020-03-24 Davood Karimi , Haoran Dou , Simon K. Warfield , Ali Gholipour

Missing data theory deals with the statistical methods in the occurrence of missing data. Missing data occurs when some values are not stored or observed for variables of interest. However, most of the statistical theory assumes that data…

When performing data analysis, people often confront data sets containing missing values. We conducted an empirical study to understand the effects of visualizing those missing values on participants' decision-making processes while…

Human-Computer Interaction · Computer Science 2021-09-21 Hayeong Song , Yu Fu , Bahador Saket , John Stasko

Evaluating generative models for synthetic medical imaging is crucial yet challenging, especially given the high standards of fidelity, anatomical accuracy, and safety required for clinical applications. Standard evaluation of generated…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Yash Deo , Yan Jia , Toni Lassila , William A. P. Smith , Tom Lawton , Siyuan Kang , Alejandro F. Frangi , Ibrahim Habli