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Network alignment (NA) aims to find regions of similarities between molecular networks of different species. There exist two NA categories: local (LNA) or global (GNA). LNA finds small highly conserved network regions and produces a…

Molecular Networks · Quantitative Biology 2015-09-30 Lei Meng , Aaron Striegel , Tijana Milenkovic

Network alignment (NA) aims to find a node mapping between molecular networks of different species that identifies topologically or functionally similar network regions. Analogous to genomic sequence alignment, NA can be used to transfer…

Molecular Networks · Quantitative Biology 2016-04-07 Vipin Vijayan , Tijana Milenkovic

Biological network alignment (NA) aims to identify similar regions between molecular networks of different species. NA can be local or global. Just as the recent trend in the NA field, we also focus on global NA, which can be pairwise (PNA)…

Molecular Networks · Quantitative Biology 2020-04-28 Vipin Vijayan , Shawn Gu , Eric Krebs , Lei Meng , Tijana Milenkovic

Our Microbiome Network Alignment Algorithm (MiNAA) aligns two microbial networks using a combination of the GRAph ALigner (GRAAL) algorithm and the Hungarian algorithm. Network alignment algorithms find pairs of nodes (one node from the…

Molecular Networks · Quantitative Biology 2022-12-13 Reed Nelson , Rosa Aghdam , Claudia Solis-Lemus

Biological network alignment aims to identify similar regions between networks of different species. Existing methods compute node "similarities" to rapidly identify from possible alignments the "high-scoring" alignments with respect to the…

Molecular Networks · Quantitative Biology 2013-11-12 Vikram Saraph , Tijana Milenković

Network (or Graph) Alignment Algorithms aims to reveal structural similarities among graphs. In particular Local Network Alignment Algorithms (LNAs) finds local regions of similarity among two or more networks. Such algorithms are in…

Social and Information Networks · Computer Science 2020-08-12 Pietro Hiram Guzzi

Network alignment (NA) compares networks with the goal of finding a node mapping that uncovers highly similar (conserved) network regions. Existing NA methods are homogeneous, i.e., they can deal only with networks containing nodes and…

Molecular Networks · Quantitative Biology 2018-03-30 Shawn Gu , John Johnson , Fazle E. Faisal , Tijana Milenkovic

Networks can model real-world systems in a variety of domains. Network alignment (NA) aims to find a node mapping that conserves similar regions between compared networks. NA is applicable to many fields, including computational biology,…

Social and Information Networks · Computer Science 2017-02-01 Vipin Vijayan , Dominic Critchlow , Tijana Milenkovic

The alignment of biological networks has the potential to teach us as much about biology and disease as has sequence alignment. Sequence alignment can be optimally solved in polynomial time. In contrast, network alignment is $NP$-hard,…

Molecular Networks · Quantitative Biology 2016-07-12 Nil Mamano , Wayne Hayes

A Multilayer Network (MN) is a system consisting of several topological levels (i.e., layers) representing the interactions between the system's objects and the related interdependency. Therefore, it may be represented as a set of layers…

Social and Information Networks · Computer Science 2023-09-15 Marianna Milano , Pietro Cinaglia , Pietro Hiram Guzzi , Mario Cannataro

Biological network alignment (NA) aims to find a node mapping between species' molecular networks that uncovers similar network regions, thus allowing for transfer of functional knowledge between the aligned nodes. However, current NA…

Molecular Networks · Quantitative Biology 2020-09-09 Shawn Gu , Tijana Milenkovic

Network alignment aims to find regions of topological or functional similarities between networks. In computational biology, it can be used to transfer biological knowledge from a well-studied species to a poorly-studied species between…

Molecular Networks · Quantitative Biology 2014-10-21 Joseph Crawford , Tijana Milenković

Sequence alignment has had an enormous impact on our understanding of biology, evolution, and disease. The alignment of biological {\em networks} holds similar promise. Biological networks generally model interactions between biomolecules…

Molecular Networks · Quantitative Biology 2019-11-25 Wayne B. Hayes

Integrating data from heterogeneous sources is often modeled as merging graphs. Given two or more 'compatible', but not-isomorphic graphs, the first step is to identify a graph alignment, where a potentially partial mapping of vertices…

Social and Information Networks · Computer Science 2018-03-13 Abdurrahman Yaşar , Ümit V. Çatalyürek

Gene Ontology (GO) terms are frequently used to score alignments between protein-protein interaction (PPI) networks. Methods exist to measure the GO similarity between two proteins in isolation, but pairs of proteins in a network alignment…

Molecular Networks · Quantitative Biology 2017-04-06 Wayne B. Hayes , Nil Mamano

Historically, Recurrent neural networks (RNNs) and its variants such as LSTM and GRU and more recently Transformers have been the standard go-to components when processing sequential data with neural networks. One notable issue is the…

Machine Learning · Computer Science 2020-06-18 Vsevolod Sourkov

Network alignment (NA) is the task of finding the correspondence of nodes between two networks based on the network structure and node attributes. Our study is motivated by the fact that, since most of existing NA methods have attempted to…

Social and Information Networks · Computer Science 2023-08-21 Jin-Duk Park , Cong Tran , Won-Yong Shin , Xin Cao

PPI network alignment aims to find topological and functional similarities between networks of different species. Several alignment approaches have been proposed. Each of these approaches relies on a different alignment method and uses…

Quantitative Methods · Quantitative Biology 2019-11-25 Sarra Ghanjeti

Searching for local sequence patterns is one of the basic tasks in bioinformatics. Sequence patterns might have structural, functional or some other relevance, and numerous methods have been developed to detect and analyze them. These…

Quantitative Methods · Quantitative Biology 2018-08-01 Braslav Rabar , Strahil Ristov , Maja Zagorščak , Martin Rosenzweig , Pavle Goldstein

Topological network alignment aims to align two networks node-wise in order to maximize the observed common connection (edge) topology between them. The topological alignment of two Protein-Protein Interaction (PPI) networks should thus…

Molecular Networks · Quantitative Biology 2022-08-29 Siyue Wang , Giles R. S. Atkinson , Wayne B. Hayes
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