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Protein classification tasks are essential in drug discovery. Real-world protein structures are dynamic, which will determine the properties of proteins. However, the existing machine learning methods, like ProNet (Wang et al., 2022a), only…

Quantitative Methods · Quantitative Biology 2024-03-27 Yi-Shan Lan , Pin-Yu Chen , Tsung-Yi Ho

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

Segmentation of ultra-high resolution images is increasingly demanded, yet poses significant challenges for algorithm efficiency, in particular considering the (GPU) memory limits. Current approaches either downsample an ultra-high…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Wuyang Chen , Ziyu Jiang , Zhangyang Wang , Kexin Cui , Xiaoning Qian

Aligning protein interaction networks (PPI) of two or more organisms consists of finding a mapping of the nodes (proteins) of the networks that captures important structural and functional associations (similarity). It is a well studied but…

Molecular Networks · Quantitative Biology 2020-10-12 Concettina Guerra , Pietro Hiram Guzzi

Protein-protein interaction (PPI) network alignment is a canonical operation to transfer biological knowledge among species. The alignment of PPI-networks has many applications, such as the prediction of protein function, detection of…

Molecular Networks · Quantitative Biology 2019-05-15 Ehsan Kazemi , Matthias Grossglauser

Network embedding is an effective method to learn low-dimensional representations of nodes, which can be applied to various real-life applications such as visualization, node classification, and link prediction. Although significant…

Machine Learning · Computer Science 2020-03-31 Shixun Huang , Zhifeng Bao , Guoliang Li , Yanghao Zhou , J. Shane Culpepper

The function of a protein is defined by its interaction partners. Thus, topology-driven network alignment of the protein-protein interaction (PPI) networks of two species should uncover similar interaction patterns and allow identification…

Molecular Networks · Quantitative Biology 2022-08-29 Siyue Wang , Xiaoyin Chen , Brent J. Frederisy , Benedict A. Mbakogu , Amy D. Kanne , Pasha Khosravi , Wayne B. Hayes

In cancer research, the comparison of gene expression or DNA methylation networks inferred from healthy controls and patients can lead to the discovery of biological pathways associated to the disease. As a cancer progresses, its signalling…

Methodology · Statistics 2015-06-17 Da Ruan , Alastair Young , Giovanni Montana

Graph neural networks (GNNs) are increasingly used to model biological systems, yet the reliability of post-hoc explanation methods for recovering meaningful molecular mechanisms remains unclear. Here, we systematically evaluate four widely…

Molecular Networks · Quantitative Biology 2026-05-22 Kyle Higgins , Ivan Laponogov , Dennis Veselkov , Kirill Veselkov

Link prediction is a fundamental task in dynamic graph learning (DGL), inherently shaped by the topology of the DG. Recent advancements in dynamic graph neural networks (DGNN), primarily by modeling the relationships among nodes via a…

Machine Learning · Computer Science 2025-04-29 Ling Wang , Minglian Han

Wireless Sensor Networks (WSNs) are essential for monitoring and communication in complex environments, where coverage optimization directly affects performance and energy efficiency. However, traditional algorithms such as the Whale…

Computational Engineering, Finance, and Science · Computer Science 2025-12-03 Junhao Wei , Yanzhao Gu , Ran Zhang , Yanxiao Li , Wenxuan Zhu , Jinhong Song , Yapeng Wang , Xu Yang , Ngai Cheong

This work presents Adaptive Local-then-Global Merging (ALGM), a token reduction method for semantic segmentation networks that use plain Vision Transformers. ALGM merges tokens in two stages: (1) In the first network layer, it merges…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Narges Norouzi , Svetlana Orlova , Daan de Geus , Gijs Dubbelman

Image retrieval-based cross-view geo-localization (IRCVGL) aims to match images captured from significantly different viewpoints, such as satellite and street-level images. Existing methods predominantly rely on learning robust global…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Xianwei Cao , Dou Quan , Shuang Wang , Ning Huyan , Wei Wang , Yunan Li , Licheng Jiao

In the last few years, Deep Learning (DL) has been showing superior performance in different modalities of biomedical image analysis. Several DL architectures have been proposed for classification, segmentation, and detection tasks in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-26 Md Zahangir Alom , Theus Aspiras , Tarek M. Taha , Vijayan K. Asari

The task of graph node classification is often approached by utilizing a local Graph Neural Network (GNN), that learns only local information from the node input features and their adjacency. In this paper, we propose to improve the…

Machine Learning · Computer Science 2024-06-18 Moshe Eliasof , Eran Treister

Temporal Graph Learning (TGL) has become a prevalent technique across diverse real-world applications, especially in domains where data can be represented as a graph and evolves over time. Although TGL has recently seen notable progress in…

Machine Learning · Computer Science 2024-02-27 Weilin Cong , Jian Kang , Hanghang Tong , Mehrdad Mahdavi

Network alignment, or the task of finding meaningful node correspondences between nodes in different graphs, is an important graph mining task with many scientific and industrial applications. An important principle for network alignment is…

Social and Information Networks · Computer Science 2021-01-25 Mark Heimann , Xiyuan Chen , Fatemeh Vahedian , Danai Koutra

Neural Architecture Search (NAS) aims to automatically excavate the optimal network architecture with superior test performance. Recent neural architecture search (NAS) approaches rely on validation loss or accuracy to find the superior…

Computer Vision and Pattern Recognition · Computer Science 2023-05-19 Joonhyun Jeong , Joonsang Yu , Geondo Park , Dongyoon Han , YoungJoon Yoo

Open-world Question Answering (OW-QA) over knowledge graphs (KGs) aims to answer questions over incomplete or evolving KGs. Traditional KGQA assumes a closed world where answers must exist in the KG, limiting real-world applicability. In…

Computation and Language · Computer Science 2026-04-16 Hussein Abdallah , Ibrahim Abdelaziz , Panos Kalnis , Essam Mansour

Wireless federated learning (WFL) enables devices to collaboratively train a global model via local model training, uploading and aggregating. However, WFL faces the data scarcity/heterogeneity problem (i.e., data are limited and unevenly…

Signal Processing · Electrical Eng. & Systems 2024-06-18 Ding Xu , Lingjie Duan , Hongbo Zhu